Generic Medication guide:
What is the preparation available under the commercial name Claritin?
The brand Claritin was registered for a preparation with active pharmaceutical substance approved in the U.S. in 1993 called Loratadine. It is an H1-histamine receptors inhibitor that suppresses the body’s answer to allergic irritants through the suppression of mediators of inflammation. These mediators are released by the granules of the mastocytes and basophils (certain body cells) when the sensibility of the body to an allergen is that occurred as a result of primarily secreted Immunoglobulin E with the Fc receptor on the surface of mastocytes and basophils. The repeated encounter with the same allergen leads to the reactivation of Immunoglobulin E that serves as a signal to degranulation of susceptible body cells mentioned above. The histamines and other inflammation mediators released from these cells in the adjacent tissues cause vasodilatation, nasal or eye discharges, irritation of nerve endings, and contraction of smooth muscles in the blood vessels. This is shown in a form of a nasal discharges, skin itching, swelling, and the inflammation in the place where the allergen contacted the body. Thus, if you have such symptoms you can buy Claritin to get rid of them.
Short drug info
|
Trade names |
Claritin, Claratyne, others |
Use in prgenancy |
AU: B1
US: B (No risk in non-human studies)
|
Routes of administration |
oral |
Legal status |
CA: OTC
UK: General sales list (GSL, OTC)
US: OTC
|
Bioavailability |
almost 100% |
Protein binding |
97–99% |
Metabolism |
liver (CYP2D6- and 3A4-mediated) |
Elimination half-life |
8 hours, active metabolite desloratadine 27 hours |
Excretion |
40% as conjugated metabolites into urine
Similar amount into the feces
|
For what types of allergies is Claritin suitable?
The formulation is suitable for a variety of manifestations of allergy. For instance, it can be utilized to cope with the symptoms of blossom-induced rhinitis or allergic rhinitis present all year around due to sensitivity to dust, animals dandruff, and other allergens. Besides, it is effective for the therapy of allergy-induced inflammation of the eyelids, persistent idiopathic urticaria, allergic swelling, bronchial asthma (as an additional means), allergic response to the bites of insects, allergic skin reaction such as rash, eczema, dermatosis, and so on. On top of that, you can buy Generic Claritin to get rid of pseudo-allergic responses to various irritants accompanied by the production of histamine.
When is the medication use unsuitable?
Although you have the indications for Loratadine use, you still shouldn’t utilize it if you are allergic to the tablets main ingredient or auxiliary substances, breastfeed, or plan to administer the medication to a child younger than two years.
Besides, it is not advised to use the antihistamine when you expect a baby. The use is possible only if your physician believes that the therapy with the drug will bring more benefit than harm.
The formulation is advised to be cautiously utilized by people with severe liver dysfunction (in some cases the lowering and reduced frequency of doses use it needed).
The preparation contains lactose. Hence, people with congenital conditions such as galactose intolerance, lactase deficiency, and glucose-galactose malabsorption must avoid using it.
Can Claritin contribute to the occurrence of negative effects?
There is no way any medicinal product could be suitable for everyone since all of us have our own individual features and can be intolerant to certain substances or develop unexpected reactions to harmless substances. For instance, in around 12% of people who use this medication it causes headache; in 8% it causes drowsiness; in 4% - fatigue; in less than 2% - focus impairment, dizziness, anxiety, insomnia, depression, dry mouth, blurred vision, pain in the ears, nausea, vomiting, and so on.
As you can see, no serious or life-threatening adverse effects are common for Loratadine. Nevertheless, if you do develop any of them when you buy Loratadine and start the therapy, especially if they are severe, immediately inform your physician and ask him or her how you can treat these symptoms.
Does Claritin interact with other substances?
It is proven that unlike other previous generations of antihistamines, Loratadine doesn’t enhance its effects in the consumption of alcohol and doesn’t potentiate the alcohol’s impact on the nervous system.
There is a potential of the interaction of the medication with all known inhibitors of CYP3A4 or CYP2D6 enzymes – the concurrent intake can cause the elevation of Loratadine in the blood plasma and respectively the elevation of the probability of negative reactions occurrence. The most widely used medications from these classes are ketoconazole, erythromycin, and cimetidine. Besides, the Loratadine contributes to 15% lowering of the concentration of erythromycin in the blood plasma. Therefore, if you use any of these medications when you plan to buy Generic Loratadine, it is preferable to discuss the safety of such combination and the possible dose adjustment with your physician.
How is Claritin taken?
The pills are taken without regards of meals.
Children older than twelve years and adults should take one pill once a day.
The dosage for children between two and twelve years of age is based on the body weight. If the weight is less than thirty kilograms (66 pounds), the dosage per day is 5 mg. If the weight is more than thirty kilograms (66 pounds), the dosage per day is 10 mg. In general, it is advised to use the tablet formulation only in kids with the weight more than 30 kg and for smaller children to use syrup.
Patients with severe liver impairment must consult a doctor before they order Claritin and start using it because they are in general not advised to use it and if they are allowed, then the dose is 10 mg once in two days (this dose regimen is suitable only for adults and children with the body weight over 30 mg/66 pounds).
Where can you buy Claritin?
here are different ways to get the medication: you can get branded medication or its cheaper generic analog from your local drugstore or order it from an online pharmacy. The second option, especially if you opt for a generic preparation, is much cheaper and not less beneficial in terms of allergy relief. We offer you to order Generic Claritin made by the leading Indian generic-making company Sun Pharma that has gained a remarkable reputation around the world for its high quality and at the same time low-cost products.
Claritin shipping
You should order as many pills as you need wherever you live as we deliver all products internationally without exceptions via standard and express mail services.
Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.
Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.
For more answers see the FAQ section
|