Generic Medication guide:
Zyrtec: what is this preparation used for?
The medical substance you can purchase under the name Zyrtec is Cetirizine, a medicinal agent included in the pharmacological group of antihistamines for systemic use and is a piperazine derivative.
The medication is effective against a variety of types of allergy manifestations and can be purchased without a prescription since 2007 even in the U.S. This fact makes the medication very attainable and suitable for the use as a first aid. Besides, if you want to buy Zyrtec even cheaper than a regular over-the-counter medication, you can in place of it seek for the product with the same active ingredient, Cetirizine, but with another trademark. These medications are named “generics”. They are the same drugs only made by the other companies.
You can think of purchasing Zyrtec or a generic of the medicine if you suffer from the symptoms of either seasonal or persistent (year-round) rhinitis, conjunctivitis (inflammation of the eyes) caused by an allergic reaction, hay fever (seasonal allergy caused by pollen of various plants and manifested in nasal symptoms, allergic eye symptoms, dermatitis, irritability, scratchy throat, cough, sometimes attacks of suffocation); chronic idiopathic urticaria, allergy-induced dermatitis, skin rash and itching, angioedema, and bronchial asthma (as a part of the maintenance therapy).
What makes Zyrtec effective against allergy? How does it act?
The anti-allergy effect of the preparation is due to its selective antagonizing (suppressing) of H1 histamine receptors. Thus, lowering the effect of histamine on the body, the preparation causes the diminishing of the spasms caused by histamine in smooth muscles of bronchi and intestines, lowering of penetrability of capillaries, prevents the development of swelling, and in general the prevention and ease of allergic reactions manifestations.
Besides the described above effect, the formulation also renders a direct anti-allergy action as it inhibits the late phase of the body cells inclusion into the process of inflammation, especially eosinophils in the skin, conjunctiva, and bronchoalveolar fluid.
During the clinical trials, Cetirizine used in the doses of 5 and 10 mg inhibited the development of papules (rash) and reddening caused by the very high levels of histamine in the skin.
The onset of the effect after a single intake of 10 mg is observed within twenty minutes and lasts for at least twenty-four hours.
Individuals with allergic rhinitis and such accompanying diseases as bronchial asthma of mild to severe stage taking 10 mg of the medication once a day experience the improvement of symptoms and no worsening of the lung condition. This proves the harmlessness of the formulation use in people with asthma.
The studies also had indicated that the utilization of Cetirizine in the high dose of 60 mg a day does not provoke a statistically significant extension of the QT interval.
When is the use of Zyrtec contraindicated?
You should not buy Generic Zyrtec if you are intolerant of the formulation’s main ingredient or auxiliary components or suffer from severe kidney function violation with creatinine clearance slower than 10 milliliters per minute. It is also contraindicated to give the pills to children younger than six years and take the pills if you are pregnant.
If you suffer from rare hereditary forms of lactose intolerance or malabsorption of glucose-galactose, you should not take Cetirizine in the form of coated tablets.
In case you aren’t sure whether you have any of these conditions or if you take any medications on a regular basis, make sure to get a consultation with a specialist prior to starting the therapy.
It is not contraindicated but not advised to buy Generic Cetirizine and use it for people with chronic kidney insufficiency, people older than 65, individuals who suffer from epilepsy or other conditions in which there is an elevated seizure activity, people with factors predisposing to urine retention, and breastfeeding women.
With what medications Zyrtec use is incompatible?
Based on the analysis of the medication’s pharmacodynamics and pharmacokinetics, the likelihood of interaction with other medicinal products is very improbable.
During the tests, there hadn’t been noticed any substantial interaction with pseudoephedrine or Theophylline.
However, the simultaneous use of Zyrtec with alcohol or other substances that have a depressive effect on the nervous system can contribute to the further lowering of concentration ability and speed of reaction.
How should you take the pills if they are not contraindicated for you?
When you buy Cetirizine, you should make sure that it is safe for you and if it is so, it is prescribed to take a single 10 mg pill once a day. It is advised to take the medication during dinner.
An alternative dosage regime is 5 mg pills taken two times daily - during the breakfast and dinner.
The above doses are for adults and children aged 12 and more years.
Children aged from 2 to 12 years are advised to be administered the drug in a form of drops by 5 mg (10 drops) or 2.5 mg (5 drops) twice a day.
People with kidney failure of mild severity should take a half of the regularly-recommended dose.
Can Zyrtec provoke the occurrence of adverse reactions?
The clinical trials of the medication had discovered that it can cause mild side effects from the part of the central nervous system including sluggishness, general weakness, lightheadedness, headache, or stimulation of the central nervous system.
Besides, sometimes when you order Zyrtec and start the therapy you can start suffering from troubled urination, slight vision impairment, dry mouth, liver function impairment, and others.
Make sure to not to neglect these or other negative symptoms if they occur and consult your physician about their minimization.
Overdose of Zyrtec
The serious overdose that may require hospitalization is when the recommended dose is raised five-fold. In this case, you can develop mainly the symptoms of the impact on the nervous system such as brain-fog, dizziness, fatigue, headache, anxiety, sedation, tachycardia, and others. Besides, troubled urination and diarrhea can develop.
The severe overdoses with the drug require promptly performed gastric lavage so you need to seek medical assistance if you took 50 mg (5 pills) or more per day.
Precautions and special recommendations
If you have any damages of the spinal cord, hyperplasia of the prostate, or any other conditions that can cause urine retention, you should consult a healthcare specialist about how can you act in case the use of the medication causes this negative symptom before you order Generic Zyrtec.
It is recommended to drink alcohol cautiously when using the preparation although the trials show that there are no significant interactions in the concentration of ethanol in the blood in the amount of 0.5 g per liter.
Caution should be rendered by people who suffer from epilepsy or any other condition that is characterized by seizures.
It is proven that Cetirizine doesn’t influence the ability to focus and reaction speed if not combined with other medications that influence the CNS yet during the first few days of the preparation use, to see how well you tolerate it and whether you do develop drowsiness while taking the drug, it is advised to avoid driving or operating any machinery.
Before you do allergy tests to see if you are allergic to any substance it is required to discontinue the therapy with Cetirizine for at least three days before the tests as such medications prevent the occurrence of skin allergic reactions.
Where can you buy Zyrtec?
Currently, the medications based on Cetirizine are sold over-the-counter in the most countries of the world but the prices per pill differ greatly. If you live in a country where it is expensive, you can always order Cetirizine from our drugstore and enjoy a low price and the best quality.
Zyrtec and all other products we offer at our online drugstore are shipped internationally so you can order the pills without any worries. All you have to do is to choose the delivery type correctly, i.e. if you need the pills as soon as possible, order express shipping, or if you can wait, you can select a cheaper standard delivery. Moreover, we pay for the delivery if your order is 170 dollars or more.
Our doctor prescribes online for free, and there is no doctor’s consultation fee.
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.
For more answers see the FAQ section