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4RX Store > Medication List > Anti Depressants drugs > Order Luvox online

Anti Depressants Medication (Luvox)

 
Generic name:
Luvox
Brand name:
Fluvoxamine
Description:
The medication marketed as Luvox is based on Fluvoxamine and is also available under other names as a generic. It is a selective serotonin reuptake inhibitor antidepressant that can be used for the therapy of adults and children older than eight years diagnosed with depression of obsessive-compulsive disorder. It can be also used during pregnancy if your therapist believes that the benefit would be greater than the risk. Find out how to use the pills to enjoy the best effect from our guide.
Indications:
Major depressive depression, Depressions of different cause, Obsessive-compulsive disorder
Benefits:
Helps to eliminates the symptoms of depression and obsessive-compulsive disorder and prevent relapses; is safe for children older than 8 years
Manufacture:
Solvay Pharmaceuticals
Solvay Pharmaceuticals
Synonyms:
Flavoxin, Flovaxin, Dumirox, Faverin, Floxyfral, Fluvoxamina, Maveral
 
   
Luvox (Generic Fluvoxamine)
 
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  Generic Medication guide:

What is Luvox and when can you use it?

The name Luvox I registered by a USA pharmaceutical company Abbott Laboratories for the medicinal substance known internationally as Fluvoxamine. The formulation had been developed not so long ago – it became available on the market in 1994. Once the exclusive patent of the developer expired, the formulation also started to be manufactured and marketed by other companies such as Indian generics makers Solvay Pharmaceuticals, Cipla, Ranbaxy, and others. These medications are cheaper than the branded Luvox but have the same composition and action. Thus, if your medical care provider prescribes you the medication with an active agent Fluvoxamine, you can either buy Luvox or a cheaper version which you can find looking for generic Luvox.
Fluvoxamine belongs to the class of selective serotonin reuptake inhibitor antidepressants. It has a similar effect to Fluoxetine (mostly known as Prozac) but starts to render its effect sooner.

Your doctor can prescribe you to take Luvox if you are diagnosed with:
- Depressive disorder of any cause including accompanied with generalized anxiety;
- Obsessive-compulsive disorder.

Please keep in mind that the same conditions can be treated with different formulations or even combinations of them based on your individual health features and healthcare provider’s opinion. Thus, we recommend you to discuss with him or her possibility of using Fluvoxamine if they didn’t prescribe it to you.

Clinical data
Trade names
Faverin, Fevarin, Floxyfral, Dumyrox, Luvox
Pregnancy category C
Routes of administration Oral (tablets)
Legal status AU: S4 (Prescription only)
CA: RX-only
UK: POM (Prescription only)
US: RX-only
Bioavailability 53% (90% confidence interval: 44-62%)
Protein binding 80%
Metabolism Hepatic (liver)
Elimination half-life 12-13 hours (single dose), 22 hours (repeated dosing)
Excretion Renal (98%; 94% as metabolites, 4% as unchanged drug

When Luvox must not be taken?

Before you buy generic Luvox, you should know that even if you have the diagnosis for which it is used you may still be unable to use it if you have any conditions in which the use of Fluvoxamine is contraindicated as it can worsen them:
- Hypersensitivity to the main or additional ingredients of the pills;
- Liver dysfunction;
- The therapy with Astemizole, Cisapride, Terfenadine, agents that inhibit MAO (including Furazolidone, Procarbazine, Selegiline, and others).

The use of Fluvoxamine is also contraindicated for children younger than eight years as the medicine safety is not sufficiently studied in pediatric patients. For this reason and because the drug is found in the breast milk, it is contraindicated to undergo the therapy and breastfeed a baby at the same time.

The use of the formulation is undesirable in the following cases:
- Epilepsy and any disorders which are associated with seizures;
- Pregnancy;
- Drug dependence;
- Mania;
- Hypomania;
- Myocardial infarction (including history).

Use of Luvox during pregnancy and breastfeeding

It is prohibited to take the pills while you breastfeed. If your doctor prescribes you the medication you can buy Fluvoxamine and use it but keep in mind that you should transfer your baby to a formula feeding.
The antidepressant can be used during pregnancy but only if the expected benefit for the mother is bigger than the risks for the unborn baby.

Luvox use and dosage regimen for different conditions

The tablets are taken entirely, swallowed without chewing with a glass of water.
- Depression in adults is treated with 50-100 mg. It must not be split and advised to be used before you go to bed. If the initial dosage is insufficient, it can be phased up to 300 mg a day but only if you don’t develop any side effects from the medication use. The dosages above 150 mg are split into several intakes with the major part intake before the bedtime.
The recommended treatment course is continued for a half of a year after the symptoms are eliminated. For the prophylaxis of relapses it is recommended to take a 100 mg pill once a day for as long as your therapist prescribes.
- Obsessive-compulsive disorder in adults is treated with 50 mg in one intake for the first three-four days. Then, it is phased up till the minimum effective one. The regular dosage is between 100 and 300 mg a day. The maximum daily dosage is 300 mg a day.
The dosages until 150 mg are not split and taken before bedtime. If the effective dosage is higher than that, it should be split into 2-3 intakes with the major share intake before bedtime.
Once the therapeutic effect is achieved, the therapy can be continued in an individually chosen dosage.
If within ten weeks of the OCD therapy no improvement is observed, a doctor should reconsider the formulation use and propose the use of another medicine.
It is advised to adjust the dosages very carefully and little by little to ensure that you take the lowest efficient dosage as the therapy can be continued for quite long periods of time.
It is advised to combine the therapy with the medicine with psychotherapy for the optimal results.
- Children can be given the medication if they are older than eight years and diagnosed with the conditions for which Luvox is indicated. The average dosage for children and adolescents is 100 mg split into two intakes with the major part taken before sleep although it is highly recommended that it would be chosen by a child psychologist. The maximum daily dosage for this group of patients is 200 mg.

Dosage adjustments of Luvox

When people with liver failure buy generic Fluvoxamine, they should start the therapy with the lower dosages and get their condition controlled by a medical specialist.

Luvox withdrawal

The therapy must not be discontinued abruptly especially if the high dosages are taken. If you want to discontinue the therapy, you should gradually diminish the dosage over the course of one to two weeks to avoid withdrawal syndrome development. If withdrawal syndrome still develops during the gradual dosage reduction or even complete discontinuation of the therapy, the intake of Luvox must be resumed in the dosages taken prior to the therapy cancellation start. Then, to discontinue the therapy without any adverse effects, a doctor can advise you on a more gradual dosage reduction.

Adverse effects of Luvox action

The most frequent adverse effects reported in relation with the use of Luvox are headache and nausea. It is also reported that they usually disappear within the first two weeks of the therapy. Other adverse events are usually associated with the disorder that is being treated and do not require additional therapy. Although if you have any chronic disorders you should consult a medical specialist about the alarming adverse effects in which occurrence you must notify your healthcare provider and possibly discontinue the use of the medicine.

The possible negative effects of Luvox use are:
- Appetite loss;
- Hallucinations, confusion, mania;
- Agitation, nervousness anxiety; sleepiness, seizures, and others.
- Rapid heart rate, hypotension (low blood pressure);
- Ache in the stomach, stool disorder, dry mouth, nausea;
- Liver function impairment;
- Increased sweating, allergic skin reactions, sensitivity to light;
- Arthralgia, fractures of bones.
- Delayed ejaculation, breast milk leaking;
- General weakness.

The trials of the medication and other substances from the class with the participation of predominantly people aged 50 and more showed the increased risk of bone fractures in this group of patients.

Adverse reaction incidence in adult OCD and depression patients (percentage of patients)

Adverse Reaction
FLUVOXAMINE
N=892
PLACEBO
N=778
Headache
22
20
Asthenia
14
6
Flu Syndrome
3
2
Chills
2
1
Palpitations
3
2
Nausea
40
14
Diarrhea
11
7
Constipation
10
8
Dyspepsia
10
5
Anorexia
6
2
Vomiting
5
2
Flatulence
4
3
Tooth Disorder
3
1
Dysphagia
2
1
Somnolence
22
8
Insomnia
21
10
Dry Mouth
14
10
Nervousness
12
5
Dizziness
11
6
Tremor
5
1
Anxiety
5
3
Vasodilatation
3
1
Hypertonia
2
1
Agitation
2
1
Decreased Libido
2
1
Depression
2
1
CNS Stimulation
1
1
Upper Respiratory Infection
9
5
Dyspnea
2
1
Yawn
2
0
Sweating
7
3
Taste Perversion
3
1
Amblyopia
3
2
Abnormal Ejaculation
8
1
Urinary Frequency
3
2
Impotence6
2
1
Anorgasmia
2
0
Urinary Retention
1
0

Percentage of patients reporting sexual adverse reactions in adult placebo-controlled trials in ocd and depression

Sexual adverse reactions
Fluvoxamine Maleate Tablets
N=892
Placebo
N=778
Abnormal Ejaculation
8%
1%
Impotence
2%
1%
Decreased Libido
2%
1%
Anorgasmia
2%
0%
Luvox overdose

The typical symptoms of this medicine overdose are nausea, vomiting, diarrhea, sleepiness, dizziness; potentially – heart symptoms such as rapid heartbeat, and so on.
The medication even taken in the large dosages is not very dangerous. The highest single dosage reorder is 12 grams after the intake of which the person fully recovered. However, there is a risk of serious health harm if an overdose of not only Luvox but also other medicines occurs.
The therapy of an overdose requires vomiting induction, gastric lavage and symptomatic treatment. If the symptoms are mild you can manage them on your own by the use of activated carbon and/or osmotic laxative.

Luvox interactions

When you order Luvox make sure you don’t take any medications with which it is not recommended to take SSRI to which this drug belongs.
- The medication must not be used with MAO inhibitors, Astemizole, Cisapride, and Terfenadine.
- The active agent of the medicine slows down the metabolism of medical products that are metabolized with the participation of CYP1A2 and 2С19, CYP2С9 and CYP3A4 as it inhibits these enzymes. The same time use can cause the accumulation of the latter medications in the blood plasma and the enhancement of their side effects.
- The serotonin adverse effects can be enhanced by the simultaneous of the drug with other medicines that influence the serotonin such as triptans, tramadol, SSRI, preparations of St. John's wort, as well as tricyclic antidepressants and Lithium that is still used in combination with Fluvoxamine in severe disorders resistant to the drug therapy but with caution.
- The formulation must not be used along with alcohol.
Please note that these are not all interactions. For a full list please read the official instruction or better consult a medical specialist if you take any medicines.
Precautions for Luvox use
- The interval between the discontinuation of MAO inhibitors use and the beginning of the therapy with Fluvoxamine or its discontinuation and the start of MAO inhibitors use must be not less than two weeks.
- People with suicidal tendencies require thorough observing especially at the beginning of the therapy as the worsening of the condition can occur.
- People of elderly age should be prescribed the lower dosages.
- The medication should be cautiously used by people who drive or operate large machinery which requires vigilance as the medication can contribute to the slowing down of reaction time.
-During the clinical tests on animals, the addiction development hadn’t been documented but the same trials hadn’t been conducted on humans. Thus, it is recommended to use it cautiously in patients with the history of drug abuse.

Mechanism of Luvox action

When you order generic Luvox you should know that its mechanism is based on the selective inhibition of serotonin reuptake at the neurons of the brain. It basically does not influence the noradrenergic processes.
The medicine is completely absorbed when taken orally and its amount active in the body, as well as the time of the effect onset, isn’t influenced by food. The maximum level of the medication in the blood plasma is observed in 3 to 8 hours after the intake.
The formulation is intensively metabolized in the liver with the formation of metabolites. The excretion and the half-life of the medication are around 13-15 hours in a single intake and 17-22 hours in a therapy, i.e. when it is used daily.

Where can you buy generic Luvox?

If you want to undergo the prescribed therapy but spend less money you should definitely order generic Fluvoxamine instead of the branded medication. You can get it much cheaper because it is a less advertised name and also if you get it online it is possible to buy it without Rx.

Shipping of Luvox

We ship all medicinal products internationally including to the U.S., UK, Australia, Canada, and so on. If you need the drug urgently, you can opt for express delivery that usually takes from 7 to 12 days. If you have pills and want to save on the next package, opt for the standard shipping which is from 12 to 30 days. Besides, if your order is 170 USD or more, we will cover the standard shipping cost.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

For more answers see the FAQ section

 

 
 
   
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