What is Zyprexa? When is this product utilized?

Is a trade name owned by the large pharmaceutical concern Eli Lilly & Company. It is basically a medicament known worldwide under an unpatented name Olanzapine which is also produced and sold by other medicinal products-making firms under different trademarks. You can buy Zyprexa either under this well-known name or look for its generic and get the same medical product several times cheaper.

Olanzapine is an atypical antipsychotic medication structurally and operationally similar to Clozapine. It has a wide range of psychopharmacological effects including antidepressant effect. You can be prescribed to take this medication if you or your family member has:
- Schizophrenia and other psychotic conditions with manifestations of aggressive behavior, anxiety, and symptoms;
- Affective disorders including bipolar disorder. The medicine is used for the stopping of acute episodes and as a long-term maintenance therapy.
- Acute manic episodes of moderate and severe severity.

Please note that this medicinal agent is also produced in a combination with Fluoxetine (Prozac) under a name Symbiax for the therapy of bipolar disorders and treatment-resistant disorders. Hence, if you wish to buy generic Zyprexa from an online med store to save on the treatment you must clarify with the psychiatrist who appointed the therapy what exact medication you or the person for whom it is prescribed needs.

Zyprexa contraindications for use

The use of the formulation is contraindicated if a patient is allergic to its components and while breastfeeding. Besides, it is highly not encouraged to be administered or if still used, be taken carefully under a psychiatrist’s or caregiver’s control in:
- Liver or kidney failure;
- Prostate enlargement;
- Seizures (including history);
- Parkinson's disease;
- Brain vessels disorders;
- Alzheimer's disease;
- Diabetes;
- Paralytic bowel;
- Glaucoma;
- Myocardial infarction;
- Heart condition;
- Breast cancer;
- Age under 18 years;
- Use of substances that elongate the QT interval especially in senior age, and others.

It doesn’t matter whether you buy Olanzapine for yourself or your close one, you have to check that a person who is about to use the formulation doesn’t have the contraindications for its use.

Use when expecting a baby or breastfeeding

During pregnancy, the medicinal product can be used but very cautiously and only at the approval of the attending doctor who must assess all risks and benefits.
During the use of Olanzapine, a woman must not breastfeed as the active agent is found in the milk.

Zyprexa dosage

- Schizophrenia: the regular initial dosage is 10 mg a day.
- Manic episodes: the regular initial dosage is 15 mg as a single-drug therapy or 10 mg a day as a part of complex therapy.
- If you buy generic Olanzapine for the avoidance of acute episodes of bipolar disorder: the regular starting dosage is 10 mg a day. Individuals who have been already receiving the formulation for manic episodes are encouraged to use it as before to prevent recurrence. When new manic or mixed episodes occur, the course is still continued but if needed, the adjustment of the dosage and the use of additional formulations to correct mood changes.
Throughout the management of schizophrenia, manic episodes, and for the avoidance of relapses of bipolar disorder, the dosage per day can be altered contingent on the individual’s response in the range between five and twenty milligrams a day. However, the daily dosage raise is indicated only after the repeated assessment of the efficacy and must not be done sooner than in twenty-four hours after the previous dosage intake.
The formulation can be used without regard to food intakes. If the cessation of the formulation use is required, it should be done by a little by little dosage lowering.
The pills are dissolving in the mouth and should not be swallowed. Alternatively, the pill can be dissolved in water and swallowed with it.

Dosage adjustments for separate groups of patients

- Senior patients in the presence of any factors that can affect the formulation metabolism or excretion must be given 5 mg a day instead of 10 mg with the following dosage raise if it is well tolerated;
- People with liver or kidney dysfunction must be given 5 mg a day instead of 10 mg with the following dosage raise if it is well tolerated;
- In the presence of one or several causes of the slow metabolism (female sex, senior age, non-smoker), the lowering of the dosage is advised. The rise of the dosage for such individuals if it is needed should be done by the minimum steps.
When it is reasonable to raise the dosage by 2.5 mg, another form of the medicament must be used (i.e. suspension).

Zyprexa adverse events

The use of the tablets can cause such adverse effects as:
- Lightheadedness, weakness,  sluggishness, sleeplessness, anxiety, aggression, agitation,  memory failure, depersonalization, phobia, obsessive-compulsive manifestations, tremor, suicidal tendencies, eye hemorrhage, glaucoma, eye pain, noise in the ears, deafness, violated taste perceptions, and others.
- Orthostatic hypotension (a sharp drop of blood pressure when standing up), slow or rapid heartbeat, palpitations, ventricular extrasystole, cardiac arrest, and others.
- Stuffy or runny nose, throat infection, coughing, dyspnea, apnea, bronchial asthma, and others.
- The increase of appetite, thirst, dryness of the mouth mucosa, enhanced saliva production, stomatitis, sickness, pain in the stomach, constipation, bloating, stool incontinence, and others.
-  Body weight increase, diabetes, hyperglycemia, and goiter.
These are not all possible adverse events yet you won’t necessarily have any of them. But if you have any chronic or acute illnesses, you should pay attention to the adverse reactions related to the affected body system as they are the most likely to occur when you order Zyprexa and start the therapy.

Adverse effects incidence in short-term, placebo-controlled clinical trials with oral Olanzapine (% of patients reporting event)

Overdose

The most frequent symptoms of an overdose recorder with Zyprexa that occurred in more than 10% of people who used it were a rapid or irregular heartbeat, agitation/aggressiveness, extrapyramidal symptoms, and depression of the nervous system up to coma. Other less frequent manifestations of an overdose included delirium, convulsions, respiratory depression, aspiration, low or high arterial pressure, and arrhythmia.
It is not advised to vomit or induce vomiting. The recommended measures are gastric lavage, activated carbon intake, symptomatic treatment, and monitoring of the life functions including blood pressure, heart function, airways function, and so on.

Zyprexa interactions

When you order generic Zyprexa you should know that its effect can be influenced by other medicines or, on the contrary, their effect lowered or side effects enhanced by Zyprexa use. Here we list only some of the significant interactions, please read the full label to know more.
- The use of activated carbon lowers the max level of the formulation in the blood by 60%.
- The use of Carbamazepine enhances the washing of the formulation twofold.
- The substances that promote the effect of CYP1A2, speed up the washing out of Olanzapine from the organism thus reducing its time of action; the antagonists of CYP1A2 slow it down.
- The formulation enhances the effect of anticholinergics and weakens the effect of Levodopa and other dopamine receptor agonists.

Zyprexa use precautions

- People with suicidal tendencies require constant supervision especially at the beginning of the therapy.
- During the therapy, liver transaminases must be regularly checked especially in people with liver dysfunction.
- The formulation must be carefully used by drivers and people whose work requires vigilance and fast speed of reaction.
- During the therapy, the use of alcohol must be restricted.
- In the onset of symptoms of the malignant neuroleptic syndrome (fever, muscle tension, irregular heartbeat, etc.) the immediate discontinuation of the formulation use is required.
- If constant desire to move is developed, a lowering of the dose and use of antiparkinsonian medication is needed.

Where to buy Zyprexa?

You can get the medication either from the regular pharmacies of order Olanzapine from our med store and save a significant amount of money on the therapy while getting the same result.

Zyprexa shipping

We ship all orders internationally. We offer express and standard shipping to the U.S., Europe, Australia, UK, Canada, and so on.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

For more answers see the FAQ section