Generic Medication guide:
What is Grisovin FP? When is it appointed?
Grisactin is a trademark owned by the pharmaceutical company GlaxoSmithKline. It is registered for the anti-fungal formulation that can be also found as Griseofulvin (the name of the active ingredient) and many other names as it is also available as so-called generic.
The effect of the formulation is based on the antibiotic fungi found in nature. This fungus suppresses the growth of certain pathogenic fungi that cause skin, nail, mucosa, and hair infections. It is effective against trichophyton, microsporoma, epidermophyton, and others. It is not suitable for different types of fungal infections, for example, candidiasis. Thus, before you buy Grisovin FP you must do tests to identify the type of pathogen and whether it can or cannot be eliminated with Griseofulvin.
If the pathogen found is responsible for the fungal infection, the medication can be appointed for:
- Skin mycosis;
- Nail mycosis;
- Genitals mycosis;
- Hair (scalp) mycosis.
Please note that it is a potent formulation that is not used as a prophylaxis as, for instance, Fluconazole that can be taken to prevent fungal infection in the use of antibiotics. Grisovin FP is used for severe and persistent infections that cannot be treated with other medicinal antifungal products including topical ointments, and so on.
Short drug information
Fulvicin, Gris-peg, Grifulvin V, others
US: C (Risk not ruled out)
Routes of administration
UK: POM (Prescription only)
From 25% to 70%
When is Grisovin FP prohibited to be used?
The contraindications for the formulation use include:
- Intolerance of Griseofulvin or auxiliary substances contained in the pills;
- Blood diseases;
- Severe renal or hepatic dysfunctions;
- Cancerous diseases.
Besides, it is not administered to toddlers aged less than two years.
Can the antifungal medication be used during pregnancy?
No, you must not buy generic Grisovin FP and use it while being pregnant or planning pregnancy as it is proven that the formulation is able to cause severe birth defects.
It is even prohibited to get pregnant within the six months after the therapy with the medication is discontinued as its residues can still influence the fetus.
Can the antifungal medication be used during breastfeeding?
It is unknown whether Grisovin FP’s levels in the breast milk are as significant as they could cause harm to the baby so it is strongly advised to transfer the baby to a formula feeding instead of breastfeeding while you take the pills.
How and for how long Grisovin FP is used?
The pills are taken with food and a tablespoon of food-grade vegetable oil.
The daily dosage must be split into to two to three intakes.
Microscopic infection in adults is treated with the individually selected dosage up to 1000 mg (8 pills). Children aged from three years are prescribed 21-22 mg per kilogram of the body weight a day. The prescribed dosage is taken every day until the appointed tests for the infection which if it comes back negative, means that the tablets are further used following this scheme: up to 1000 mg are taken every other day for two weeks; during the next two weeks, the same dosage is taken only two times a week.
Nail fungal infection, ringworm of the scalp, and favus of the scalp in adults who weigh less than 50 kg is treated with 625 mg or 5 tablets. In the body mass exceeding 50 kg, for every 10 kg additionally 125 mg are given a day. However, the maximum daily dosage must not exceed 1000 mg (8 pills). Children and adolescents are treated with 16 mg per kilogram of the body weight a day.
The treatment duration depends on the severity and persistence of the condition. In resistant mycoses, i.e. those that are not quite well responding to the therapy, the therapy can be continued for up to a year.
Please note that these are general recommendations and you must follow your doctor’s instructions instead of them if they differ.
Possible negative effects of Grisovin FP
When you buy Griseofulvin and start using it, you should know that it can cause certain negative symptoms. They do not necessarily will develop in your case but if you have any chronic or acute conditions the likelihood is higher.
- Digestive system: indigestion, nausea, diarrhea stomach ache, bloating, etc.
- Allergic reactions: skin rash, eczema, urticaria, etc.
- Central nervous system: vertigo, confusion, headache, etc.
- Blood: acute lowering of the count of white blood cells, decrease in the number of leukocytes;
- Other: candidiasis stomatitis, sensitivity to light, lupus-like syndrome.
In case you develop any adverse effects, inform your doctor immediately as some of them require immediate discontinuation of the therapy and symptomatic treatment.
Overdose signs and treatment
In clinical practice, there hadn’t been any cases of overdose with Grisovin FP. Still, it is possible that in the use of the increasing dosages of the medication you can develop any of the adverse effects listed in the previous section in a more severe form.
What medications influence Grisovin FP effect?
There are medications that interact with Grisovin FP either influencing its effect or, on the contrary, their effect is influenced by this antifungal agent. Here you can see some of the interactions, for the full list, please see the instruction you will get with the pills.
Grisovin FP lowers the efficiency of indirect anticoagulants and estrogen-containing medicines including birth control pills.
Simultaneous use with barbiturates leads to the diminishing of the antifungal effect of Griseofulvin.
The use of the medication with cyclosporine leads to the decrease of the concentration of the latter in the blood plasma.
Methadone level in the blood is substantially decreased by the use of Griseofulvin so the dose lift or more frequent use is recommended.
The medication can also influence the effectiveness of diabetic medications, other formulations that are metabolized in the liver as it induces the enzyme responsible for the elimination of many medicines, etc.
Do not combine the medication with alcohol as it can severely damage your liver.
If you currently take any medications or plan on using them when you buy generic Griseofulvin, inform your doctor about that so he or she would be able to advise you on the safety of such combinations or dosage adjustments.
The medication must be carefully used in increased sensitivity to penicillin antibiotics and in poor blood coagulation.
People whose work requires fast reaction and focus are either not appointed this medication or should take a sick leave when they undergo the therapy with the daily use of the pills.
During the therapy, it is advised to take ascorbic acid and vitamin B supplements.
Throughout the whole therapy with Grisovin FP you should refrain from drinking any alcoholic drinks.
Before you order Grisovin FP, even though you can do so without a prescription at our online drugstore, you must consult a doctor.
In case of even the mildest kidney impairment, it is contraindicated to take the pills without prior consulting a doctor.
During the therapy, the function of the kidneys liver and the blood composition must be regularly checked. If any deviations from the norm occur, the treatment must be discontinued without any delay.
It advised avoiding direct sunlight in the course of the therapy as the formulation can increase the risk of sunburns.
Where can you purchase Grisovin FP?
The best way to save on the prolonged therapy with the medication is to order generic Grisovin FP from our med store. We offer the lowest prices on the market for the qualitative generic medications made only by the most reputable pharmaceutical companies. Besides, we provide free online consultation with a qualified doctor and offer you to save on refill Rx from your healthcare provider. If you make repeated orders, you can also enjoy bonus pills and special discounts.
Grisovin FP shipping
4RXStore ships internationally to all countries of the world, to the U.S., UK, Australia, Canada, European Union, Japan, and so on. We offer you free standard shipping on $170 or more orders and bonus pills with every next order. All orders are accompanied by the tracking numbers so you could see where your package is at all times.
Our doctor prescribes online for free, and there is no doctor’s consultation fee.
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.
For more answers see the FAQ section