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4RX Store > Medication List > Generic Anti Inflammatories drugs

Generic Anti Inflammatories drugs


In this category of our online med store, our customers can find anti-inflammatory formulations suitable for the therapy of such illnesses as bowel inflammatory disorders including different types of colitis and Crohn’s disease, and various types of arthritis including rheumatoid arthritis, osteoarthritis, juvenile arthritis, and so on.
In this section, we do not offer the most known anti-inflammatory compounds, i.e. nonsteroidal anti-inflammatory medicines, because they are unsuitable for the therapy of inflammatory bowel disease since they themselves irritate the stomach and can promote ulceration of the stomach and duodenum. The medicinal products for colitis form the class of aminosalicylates, the formulations that contain 5-aminosalicylic acid. Namely such anti-inflammatory medications you can buy from our med store.
As for the therapy of arthritis, multiple various medications can be used for its treatment including NSAIDs and other anti-inflammatories such as the ones available in this section of our med store. Primarily, however, are used NSAIDs, and the other anti-inflammatory medicines are added to the therapy if their effect doesn’t provide the expected results.

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Symptoms of inflamed bowel disease

There are different types of bowel diseases including several types of colitis and Crohn’s disease. Although they differ, they have common signs and symptoms such as:
- Pain in the abdomen including acute ache;
- Stool violation (diarrhea or constipation);
- Frequent bloating and gases release;
- Nausea.

Reasons for inflammatory bowel diseases development

You should buy anti-inflammatory medicines only after you get a precise diagnosis that includes the identification of the causes of the disease which include:
- Poor/improper diet;
- Alcohol abuse;
- Bowel infections, worms, dysentery;
- Stomach disease;
- Use of medications that violate the normal flora in the intestines;
- Congenital disorders of the intestines.

Diagnosis of colitis

Any type of colitis is diagnosed based on the pain in the abdomen, changed stool, and frequent bloating. To confirm the diagnosis the examinations of the large intestine are needed such as: x-ray, endoscopic examination, and histological analysis. A great diagnostic value is attributed to sigmoidoscopy and colonoscopy. Sometimes, coprological and bacteriological studies of feces are necessary.

Therapy of inflammatory bowel disease

In the therapy of colitis, the major if not the most important factor is diet. The diet should consist of frequent intake of small portions of food that doesn’t irritate the bowel such as porridge, boiled or steamed vegetables (some of them), lean meat, and the exclusion the foods that irritate the intestine such as rich broths, fat meat, pickles, chocolate, alcohol, coffee, soda, raw vegetables, etc. Nutrition should be high in calorie and include foods rich in vitamins and proteins, and exclude coarse vegetative fiber and animal fats. In the most severe cases, the food must be consumed only in a form of puree (mash).
The treatment with the medicinal products is mainly aimed at the rapid stopping of the acute episode. Then, the therapy is adjusted for the prevention of progression and relapses of the disease. If the inflammation is spread on a short length of the intestines and is of mild to moderate severity, the therapy can be done at home. In case of total and left-sided lesions due to a greater severity of the symptoms of the disease and greater organic changes are treated at the hospital. The medications prescribed for the treatment of ulcerative colitis are conventionally divided into two groups: the first, combining basic anti-inflammatory medicines from the group of aminosalicylates formulations that contain 5-aminosalicylic acid, immunosuppressants, and corticosteroids. The remaining drugs are either in the clinical study stage or used as auxiliary ones. At our med store, you can buy anti-inflammatory drugs, corticosteroids, immunosuppressants, and herbal medications for additional effect.

Types of colitis

- Spastic colitis or irritable bowel syndrome is manifested in bloating, spasms, and bowel functioning impairment. It is considered a mild condition that occurs as a result of nervous stress, fatigue, overworking, etc.
- Chronic colitis is an inflammatory dystrophic changes in the large intestine accompanied by motor and secretory dysfunctions. The inducing agents can be infectious diseases (dysentery, salmonella, etc.), exposure to toxic substances, medicines, etc.
- Acute colitis is an acute inflammation of the mucous membrane of the small intestine, and sometimes the stomach. The causes of the development of acute colitis are food, non-bacterial poisoning, viral infections, exposure to toxic substances, etc.
- Pseudomembranous colitis is a serious, acute disease of the bowel, developing as a complication of antibiotic therapy. Clostridium difficile is found in 10-20% of patients. The illness develops due to the resistance of Clostridium difficile to antibiotics that suppress the vital activity of the intestinal flora. It is necessary to diagnose the disease in time and to cancel the antibiotic that caused diarrhea.
- Erosive colitis is an inflammatory process occurring in the stomach mucosa and the duodenum with the formation of ulcers in the duodenum.
- Ischemic colitis is an inflammation in the digestive tract caused by a lesion of blood vessels that does not lead to tissue necrosis. Various diseases and pathological processes lead to a decrease in blood flow in the mucosa and chronic ischemia of the colon. There are the main groups: the disordered of veins, small vessels, non-occlusive factors, and the occlusion of the main arteries. Violation of the intestinal blood flow badly affects the function of the colon.
- Lymphocytic colitis is a form of chronic inflammatory bowel disease. Histologically, lymphocytic colitis is characterized by a diffuse increase in the number of interepithelial lymphocytes. Sometimes the transformation into collagen lymphocytic colitis occurs over time. The latter is characterized by a histologically subepithelial homogeneous deposition of collagen fibers 10-100 mm in thickness. The reasons remain unclear.
- Alcohol-induced colitis is developed in people who frequently consume large amounts of alcohol. This type of colitis accompanies chronic pancreatitis with the impairment of lipids metabolism. It occurs as a result of replacement of the healthy intestinal flora with a pathologic one under the influence of alcohol. The illness is eliminated by the cessation of alcohol use.
- Nonspecific ulcerative colitis is a chronic relapsing intestinal illness of immune nature. It is characterized by diffuse inflammation of the mucous membrane of the large intestine. There are no precise reasons for the development of the illness.
- Atonic colitis is a disease that occurs in the elderly and senile age. In people with this form of colitis, the motor function of the gut is sharply reduced and the intestine is filled with feces. Constipation that leads to hemorrhoids is the main complaint. Poor emptying of the bowel and its overflow causes loss of appetite, a decrease in vitality.
- Hemorrhagic colitis is characterized by acute bloody diarrhea, caused by Escherichia coli. Some Gram-negative strains of Escherichia coli are capable of damaging the walls of the colon, the endothelium of blood vessels. Such toxins cause a disease similar to dysentery.
- Radiation colitis is the damage to the intestines caused by ionizing radiation on the body. In individuals with cancer treatment receiving radiotherapy for tumors of the lymph nodes or small pelvis, radiation damage to the intestine develops more often. Clinical symptoms are not always accompanied by acute mucosal damage.
- Distal and left-sided colitis is the inflammatory process that involves 30-40 cm of the colon. If the splenic angle is affected, left-sided colitis is diagnosed. Infectious colitis is an acute disorder of the large intestine function. The disorder can be induced by a number of bacteria. Such bacteria can be Salmonella, Yersinia enterocolitica, Clostridium, Shigella, Camphylobacter, and E. Coli.

Anti-inflammatory therapy of rheumatoid arthritis

The first-line anti-inflammation therapy in the inflammation of joints and bones are nonsteroidal anti-inflammatory drugs. However, sometimes their effect is insufficient or a patient diagnosed with the condition cannot use them for various reasons such as for instance, a stomach ulcer. Then, additional medications can be appointed such as aminosalicylates, the formulations that contain 5-aminosalicylic acid which you can buy at our pharmacy.

4RXStore offers you to buy the following anti-inflammatory medicines:
- Generic Asacol (Mesalamine) made by Sun Pharma is a 5-Aminosalicylic acid used to treat ulcerative colitis and Crohn's disease. Similar to other salicylates, it is an inhibitor of prostaglandin synthesis which explains its anti-inflammatory activity. The medication is contraindicated to be used in hypersensitivity to salicylates, severe dysfunction of the liver and kidneys, peptic ulcer of the stomach and duodenum.
- Azulfidine (Sulfasalazine) made by IPCA A dose of life is an anti-inflammatory formulation, sulphamide derivative of 5-Aminosalicylic acid developed back in 1950s and still widely used for colitis with the development of ulcers, Crohn’s disease therapy and prophylaxis of relapses, rheumatoid arthritis, and juvenile rheumatoid arthritis. The formulation is prohibited to be taken in blood diseases, porphyria, severe liver dysfunction, severe renal dysfunction, deficiency of the enzyme glucose-6-phosphate dehydrogenase, children under 5 years, hypersensitivity to sulfonamides and derivatives of salicylic acid.

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