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4RX Store > Medication List > Anti Inflammatories drugs > Order Azulfidine online

Anti Inflammatories Medication (Azulfidine)

Generic name:
Brand name:
Azulfidine is a trade name of the active ingredient Sulfasalazine that is an anti-inflammatory agent used for the therapy of ulcerative colitis, Crohn’s disease, and rheumatoid arthritis in adults and children aged older than six years. To prevent relapses, the medication can be used without interruptions for an indefinite amount of time if it is well tolerated. The dosage recommendations, precautions, adverse effects, and other useful information can be found in the guide below.
Ulcerative colitis therapy and prevention of relapses, Crohn’s disease, Rheumatoid arthritis, Juvenile polyarticular or oligoarticular rheumatoid arthritis
The medication helps to suppress the acute intestinal inflammation and prevent the relapses of acute episodes as well as relieves inflammation in joints in arthritis
IPCA - A dose of life
IPCA - A dose of life
Azulfidine (Generic Sulfasalazine)
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Order Generic Sulfasalazine Buy Azulfidine 500mg


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  30 tabs
$60.00 ($64.62)








  60 tabs
$110.00 ($118.52)








  90 tabs
$150.00 ($173.53)








  120 tabs
$190.00 ($217.78)








  180 tabs
$240.00 ($294.53)








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  Generic Medication guide:

What is Azulfidine and when should it be used?

Azulfidine is a commercial name registered for an active pharmaceutical substance called Sulfasalazine synthesized in the 1950s and since then used for the therapy of inflammatory diseases. The substance is included in the group of aminosalicylic acid and the like substances. Since it was developed almost 70 years ago, today it is available under a variety of trade names and you can buy generic Azulfidine instead of the branded medication to get the same therapeutic effect several times cheaper.

Your doctor may appoint you to use the formulation based on Sulfasalazine for the:
- Induction and supporting of remission in ulcerative colitis and Crohn’s disease;
- Therapy of rheumatoid arthritis in adults in the insufficient efficiency of NSAIDs.
- Therapy of juvenile single-joint or multiple-joint rheumatoid arthritis.

Besides, the medication is used off-label for the treatment of idiopathic urticaria when antihistamines are not effective and for the liver cirrhosis treatment and prevention of scars formation in the liver tissue.
If you have the conditions for which the medication is suitable and want to buy Azulfidine without your physician prescribing this formulation, we advise you to discuss this therapy with your medical care provider and follow their advice. We have various medications for inflammatory bowel disease and arthritis so you would without any trouble find the formulation that your doctor prescribed you.

Clinical data
Trade names
Azulfidine, Salazopyrin, Sulazine, others
Pregnancy category
Routes of administration
By mouth
Pharmacokinetic data
Elimination half-life
5-10 hours

Azulfidine contraindications for use

The formulation use is contraindicated for people with increased sensitivity to the active substance of the pills, its metabolites, and salicylates.

Besides, it must not be used in:
-  Intestinal or urinary tract obstruction;
- Porphyria;
- Severe kidney dysfunction with the creatinine clearance less than 30 ml per minute.
- Severe liver dysfunction;
- History of severe asthma attacks, urticaria, or other allergic reactions caused by caused by acetylsalicylic acid or other NSAIDs;
- Children younger than six years.

Azulfidine use during pregnancy

Your doctor can tell you to buy Sulfasalazine only if other medications will do more harm than this one and when the use of the anti-inflammatory medication is vital. In this case, the drug is used in the lowest effective dosage. Otherwise, the medication is contraindicated to be used while expecting a baby and breastfeeding.

Azulfidine dosing and therapy duration

The pills should be swallowed with a sufficient amount of water without being crushed or chewed.
- The treatment of ulcerative colitis and Crohn’s disease in adults is made with the dosages chosen depending on the severity of the condition. The severe and moderate severity diseases are treated with 2-4 pills taken four times a day combined with steroids or without them. The night interval between the intakes must not exceed eight hours. The mild disease is treated with 2 pills taken four times a day. Once the remission is achieved, the dosage must be gradually lowered till four pills a day. This dosage must be taken on a constant basis as in the termination of the therapy even several years after an acute episode the risk of the relapse increases fourfold.
- The therapy of ulcerative colitis and Crohn’s disease in children is treated with the dosages chosen depending on the body mass. The acute phase dosages are from 40 to 60 mg per kg of the body weight a day. The maintenance therapy is made with 20-30 mg per kg of the body weight a day.
- Patients who buy generic Sulfasalazine to treat arthritis and had already been using nonsteroidal anti-inflammatory drugs for long periods of time can develop stomach sensitivity so they need to start the therapy with one pill a day gradually raising the dosage by one pill every week till the daily dosage is one pill taken four times a day or two pills taken three times a day depending on the efficiency and tolerance of the medication. The effect of the medication develops slowly and the patients can be unable to see any results even after the six weeks of the therapy.
- The therapy of juvenile polyarticular or oligoarticular rheumatoid arthritis is possible for children older than six years. The dosages are from 30 to 50 mg per kg of the body weight split into four equal intakes. The usual daily dosage is 2000 mg a day. To lower the likelihood of digestive tract side effects, the therapy should be started with 1⁄4 of the planned supporting dosage with the subsequent increase of it by 1⁄4 every week till the achievement of the planned daily dosage.
Please note that these are general recommendations and the optimal therapy for you must be chosen by a healthcare specialist who knows your illness history.

Azulfidine adverse effects

- Nervous system: headache, dizziness, weakness, fatigue, sleep disturbance, hallucinations, peripheral neuropathy, ataxia, convulsions, and tinnitus.
- Cardiovascular system and blood: leukopenia, thrombocytopenia, anemia, and other.
- Digestive system: dyspeptic phenomena: nausea, vomiting, diarrhea, abdominal pain, bloating, anorexia, an admixture of blood in feces, drug-induced hepatitis, and pancreatitis.
-Genitourinary system: violation of kidney function, interstitial nephritis, transient (passing) oligospermia and infertility.
- Allergy: skin rash, toxic epidermal necrolysis, Stevens-Johnson syndrome, and anaphylactic shock.
- Other: photosensitization, fever, and interstitial pneumonitis.

The likelihood of the adverse events differs with the lowest probability of the most severe disorders occurring. However, if you have any disorders prior to starting the therapy, chances are that you will develop the adverse events on the part of those systems or aggravation of your conditions. Thus, you must discuss all of the conditions that you have and how they can be influenced by the formulation with your doctor.
The most frequent adverse events associated with Azulfidine use are low appetite, headache, nausea, and indigestion. These reactions occur in about 1/3 of patients. In one in thirty individuals, such reactions as itching, skin rash, fever, and others develop. The other listed adverse effects occur even rarer.

Adverse events in 2 eight-week placebo-controlled trials experienced by at least 1% of the Azulfidine group and at a rate greater than placebo

Adverse Reaction
2.4 g/day
(n = 177)
4.8 g/day
(n = 179)
(n = 179)
10 (5.6%)
6 (3.4%)
1 (0.6%)
7 (4%)
5 (2.8%)
5 (2.8%)
Liver Function Test Abnormal
1 (0.6%)
4 (2.2%)
2 (1.1%)
2 (1.1%)
1 (0.6%)
2 (1.1%)
2 (1.1%)
Note: Adverse reactions for which the placebo rate was equal or exceeded the rate for at least one of the Azulfidine treatment groups were abdominal pain, dizziness, dyspepsia, and nausea.


Azulfidine interactions

Before you order Azulfidine, you need to check with your doctor that you don’t take any medicines which effect will be influenced by this formulation or vice versa:
- The formulation lowers the absorption of folic acid and Digoxin.
- The formulation enhances the effect of anticoagulants, anticonvulsants, and oral hypoglycemic medications.
- Azulfidine elevates the risk of adverse reactions development in the use of cytostatics, immunosuppressants, hepato- and nephrotoxic agents (drugs toxic to the liver and/or kidneys).

Overdose signs and therapy

The symptoms of an overdose are nausea, vomiting, pain in the abdomen, dizziness, and others.
For the therapy are indicated: gastric lavage, measures to cope with the symptoms, and forced diuresis (urination).

Azulfidine precautions

The medication must be cautiously appointed for people with liver or kidney disease, bronchial asthma, or history of severe allergic reactions. During the therapy, it is advised to monitor the blood picture and liver enzymes level regularly.
The patients must be informed that the use of the medication can cause the occurrence of the orange-yellow color of skin, urine, and/or soft contact lenses. They also must be informed that they can develop adverse reactions that require a doctor’s supervision and therapy. For instance, a sore throat, fever, paleness of the skin, or yellowing of the skin can be a sign of a serious blood disorder. Thus, in the manifestation of any of these symptoms, a patient must right away seek medical assistance.

Where can you buy Azulfidine?

For the persistent effect, the pills of this medication must be taken for long periods of time, sometimes even a lifetime. So not to get broke, it is cheaper and easier to order generic Azulfidine pills in bulk from our med store instead of the branded medication. This way you will save on the pills, Rx, and additionally get bonus pills and free delivery if you order on more than $170.

Azulfidine shipping

We ship internationally within 7-25 days based on the selected delivery method. We ship to the U.S., UK, Australia, Canada, and all other countries.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

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Product Reviews:

Feb / 04 / 2017 Isabella Howard   USA, Memphis
  Have been on sulfasalazine for a year since being diagnosed with rheumatoid arthritis. This drug improves my condition.

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