Generic Medication guide:
What is the medicinal product sold as Augmentin? When is it indicated to be used?
Augmentin is one of the brands of the British pharmaceutical company GlaxoSmithKline. This brand is used for the marketing of an antibiotic based on Amoxicillin and Clavulanic acid. This combination medication is effective against a broad range of bacteria-induced illnesses with Clavulanic acid protecting the active agent from the degenerative effect of beta-lactamases, the bacterial enzymes that make the bacteria insusceptible to penicillin class formulations and cephalosporins. Amoxicillin is a penicillin group antibiotic so the formulation is much more effective against the bacteria with beta-lactamases when it is paired with Clavulanic acid.
If your healthcare provider tells you to buy Augmentin, you can as well get the medication under another name made by the different producer. Such medicines can be found if you look for generic Augmentin.
The treatment course with the formulation is suitable in case one of the below-listed illnesses is provoked by the pathogen that can be liquidated with Amoxicillin:
- Confirmed acute sinusitis;
- Otitis media;
- Confirmed flare-up of bronchitis;
- Pneumonia;
- Urinary tract bacterial illnesses;
- Skin and soft tissue bacterial infections (including infected animal bites);
- Bones and joints bacterial infections.
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Combination medication made of
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Amoxicillin |
Penicillin antibiotic |
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Clavulanic acid |
Beta-lactamase inhibitor |
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Clinical data
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Trade names |
Augmentin, Clavulin, other |
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Pregnancy category |
AU: B1
US: B (No risk in non-human studies) |
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Routes of administration |
by mouth, intravenous |
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Legal status
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Legal status |
AU: S4 (Prescription only)
CA: RX-only
UK: POM (Prescription only)
US: RX-only |
Prior to buying generic Augmentin for any of these diseases, please make sure to get the precise diagnosis and susceptibility test that proves the formulation is effective against the infection you have.
Augmentin prohibitions for use
The use of the formulation is unsafe and therefore contraindicated for people with:
- Increased sensibility to the ingredients of the pill;
- Allergy to beta-lactam antibacterial products including penicillins and cephalosporins.
- Previous jaundice or liver dysfunction induced by the use of amoxicillin with Clavulanic acid.
- Impaired kidney function with cc less than 30 ml per minute;
- Phenylketonuria, i.e. a hereditary disease related to the violation of the metabolism of amino acids.
The formulation is also must not be used in kids younger than three months as its safety in this category of patients isn’t proven.
Use of the formulation in pregnant women
A pregnant woman must not buy Amoxicillin and use it like the other medicines especially during the first trimester of pregnancy besides the cases when her healthcare provider believes that the course with the antibiotic is vital.
Both components of the pills are found in the breast milk thus it can be harmful to a baby if a mother breastfeeds while taking Augmentin or its generic.
Augmentin dosing
The formulation must be utilized in compliance with the official recommendations on the therapy with antibiotics and data on the local sensitivity to the medication if they are available. The sensibility of the bacteria to the formulation is different in different regions and can change over time. At a doctor’s discretion, a susceptibility test must be done to be sure that the bacteria that caused your disease will be eliminated by Augmentin.
The dosages of the formulation are chosen by a physician or a narrowly specialized medical specialist based on the expected microorganisms and their susceptibility to the formulation, severity of the disease, spread and localization of the infection, age, body mass, and kidney function.
If necessary, a doctor can recommend you to use alternative forms of Augmentin, i.e. with higher amoxicillin dosage and/or with a different ratio of amoxicillin/clavulanic acid.
Below you can find the general recommendations but you must follow your healthcare provider’s instructions instead of them if they are different when you buy generic Amoxicillin.
- Adults and kids with the weight over 40 kg must take the total daily dosage of 1500 mg or three 500/125mg pills.
- For children aged from six years and with the body mass from 25 to 40 kg, the maximum daily dosage is 2400/600 mg or 4 tablets.
If for the therapeutic course the higher dosages of amoxicillin are needed, other combinations of these components must be chosen to avoid giving patient higher dosages of clavulanic acid.
The duration of the therapy is based on the response of the disease to the therapy. Some infections, for instance, osteomyelitis, require long duration therapy courses. Nevertheless, the therapy must not be continued over fourteen days without the re-evaluation of the patient’s condition.
The daily dosage must be split either into three intakes every 8 hours or two intakes every 12 hours.
Senior patients do not require dosage adjustments unless they suffer from kidney function impairment.
Individuals with kidney failure and creatinine clearance over 30 ml per minute do not require the dosage adjustment. The instructions for people with slower creatinine clearance must be given by their doctors.
Dosing in pediatric patients from 12 weeks (3 months) and older
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INFECTION
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DOSING REGIMEN
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Every 12 hours
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Every 8 hours
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200 mg/5 mL or 400 mg/5 mL oral suspensiona
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125 mg/5 mL or 250 mg/5 mL oral suspensiona
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Otitis media, sinusitis, lower
respiratory tract infections, and more
severe infections
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45 mg/kg/day every 12 hours
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40 mg/kg/day every 8 hours
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Less severe infections
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25 mg/kg/day every 12 hours
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20 mg/kg/day every 8 hours
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Amount of water for mixing oral suspension
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Strength
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Bottle Size
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Amount of Water for
Reconstitution
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Contents of Each Teaspoonful (5 ml)
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125 mg/5 mL
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75 ml
100 ml
150 ml
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67 ml
90 ml
134 ml
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125 mg amoxicillin and 31.25 mg of clavulanic acid as the potassium salt
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200 mg/5 mL
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50 ml
75 ml
100 ml
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50 ml
75 ml
95 ml
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200 mg amoxicillin and 28.5 mg of clavulanic acid as the potassium salt
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250 mg/5 mL
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75 ml
100 ml
150 ml
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65 ml
87 ml
130 ml
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250 mg amoxicillin and 62.5 mg of clavulanic acid as the potassium salt
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400 mg/5 mL
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50 ml
75 ml
100 ml
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50 ml
70 ml
90 ml
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400 mg amoxicillin and 57.0 mg of clavulanic acid as the potassium salt
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Interactions
Before you order Augmentin, if you use any medicinal products or plan to start using them soon, you must check the instruction for their compatibility with Augmentin.
- The use of Augmentin along with Probenecid is not encouraged as the later elevates the level of the antibacterial formulation in the blood through interfere ring with its washing out from the body.
- The concurrent of the antibacterial product with allopurinol can contribute to the elevation of the skin allergic reactions occurrence.
- Penicillins to which this antibiotic belongs can slow the washing out of methotrexate from the organism, so the concurrent use these medications may raise the toxicity of methotrexate and thus is not encouraged.
- The antibiotic can negatively affect the effect of oral birth controls through the creation of the imbalance of the bad and good flora in the bowel and the absorption of estrogens respectively.
- The formulation can enhance the anticoagulant (blood clotting slowing down) effect of certain anticoagulants and therefore the prothrombin time must be frequently monitored in such patients in the therapy when the drugs are combined with Augmentin.
Precautions
Before you order generic Augmentin, besides establishing whether the medication will be effective against the bacterial infection you have, it is also necessary to check your medical history to see whether you have ever had an allergy to penicilins and/or cephalosporins or not. If you are allergic to those medications, there is a high risk that you will develop a severe allergic reaction to this formulation which can be even lethal.
In case of any allergic reaction occurrence the therapy must be immediately stopped and an alternative medication use initiated.
Anaphylaxis, i.e. the most dangerous and quickly developing allergic reaction requires emergency help.
In case an infectious mononucleosis is suspected, Augmentin must not be used as the disease with the use of this antibiotic can induce a measles-like skin rash, which makes it hard to make the correct diagnose.
The long-term therapy with the formulation can cause a superfluous duplication of irresponsive microorganisms, i.e. those that cannot be eliminated with this formulation.
If the long-term therapy is prescribed, it is recommended to regularly check the blood condition, liver and kidney function.
To minimize the negative effects connected to the violated function of the gastrointestinal tract, it is advised to take the dosages prior to taking the meal.
The pills must be used within a month after the foil packaging had been opened.
Since the medication use can cause dizziness, it is preferable to refrain from driving or operating any large machinery when undergoing the therapy.
If a woman uses oral contraceptives, she should also use barrier contraception when taking Augmentin to prevent an unplanned pregnancy as the antibiotic lowers contraceptive tablets’ effect.
Where to purchase Augmentin?
To enjoy the lowest price and the greatest effect, you can order generic Augmentin from our med store right from this webpage even without Rx.
Augmentin shipping
We perform shipping to all countries. You can order Augmentin shipping even to the UK or the US where it is a prescription medication and rest assured that you will receive it.
Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.
Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.
For more answers see the FAQ section
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