Generic Medication guide:
What is Doxycycline Hyclate? When is it used?
Doxycycline Hyclate available under the names Doxycycline and others is a semi-synthetic antibiotic from the class of tetracyclines with a broad range of effect. It is classified as the bacteriostatic and antibacterial medication. The formulation is available both as the branded drug and a generic. If you need to buy Doxycycline and want to save, look for a generic drug that can have a different name but always has the name Doxycycline Hyclate on the pills package.
The indications for the medication use are infections caused by the susceptible pathogens which include:
- Diseases of the airways such as pneumonia, sinusitis, tonsillitis, bronchitis, and others.
- Urinary tract infections.
- Sexually transmitted bacterial infections.
- Skin infections.
Clinical data
|
Trade names
|
Doryx, Doxyhexal, Doxylin among others
|
License data
|
US FDA: Doxycycline
|
Pregnancy category
|
AU: D
US: D (Evidence of risk)
|
Routes of administration
|
By mouth, IV
|
Legal status
|
Legal status
|
AU: S4 (Prescription only)
UK: POM (Prescription only)
US: RX-only
|
Pharmacokinetic data
|
Bioavailability
|
100%
|
Protein binding
|
90%
|
Metabolism
|
Liver
|
Elimination half-life
|
15-25 hours
|
Excretion
|
Urine (40%)
|
When is Doxycycline contraindicated?
Do not buy generic Doxycycline if:
- You have hypersensitivity to the medication;
- You have porphyria;
- You have a severe liver failure;
- Are pregnant or breastfeeding;
- For children younger than 9 years.
How is Doxycycline used?
Adults and children aged 12 and older with the body mass over 45 kilograms are treated with 200 mg at the first day of the acute infection treatment either in one intake or by 100 mg with an interval of twelve hours. During the following days, the dosage is 100 mg a day. The therapy of severe infections and especially chronic urological infections the dosage of 200 mg is taken once a day for the whole therapeutic course.
The pills are taken with food or after a meal to minimize the risk of esophagus irritation. It is advised to wash the pills down with a glass of water or milk. It is also recommended to swallow the pills standing or sitting and in the sufficient time before sleep to avoid irritation of the esophagus.
The duration of the therapy is set individually by a doctor and must be continued for 24-48 hours after the symptoms disappear.
In streptococcal infections, the formulation must be used for ten days to avoid the development of rheumatic fever or glomerulonephritis.
You can buy Doxycycline Hyclate without Rx at our med store but we advise you to consult a doctor for a proper and safe therapy.
Dosage adjustments
No dosage adjustments are required for senior patients and people with kidney dysfunction. However, it is not recommended to use this medication in elderly patients if there is an alternative since it can cause ulceration of the stomach and esophagus.
Overdose
The acute overdose of the medication rarely happens. The symptoms can be renal parenchymal damage, pancreatitis development, and strengthening of other adverse reactions. The therapy implies gastric lavage and symptomatic therapy. Hemodialysis is not effective.
Doxycycline Hyclate adverse effects
The use of the medication can be associated with the following adverse effects:
- Nausea,
- Diarrhea,
- Difficulty swallowing,
- Irritation or ulceration of the esophagus,
- Hemolytic anemia,
- Blood composition disorders;
- Fungal infections and infections caused by resistant bacteria;
- Allergic reactions.
Interactions of Doxycycline Hyclate with other medicines
Before you buy generic Doxycycline Hyclate, keep in mind that it can negatively interact with some medications.
- It potentiates the effect of derivatives of coumarin and sulfonylurea;
- The medication suppresses the effect of penicillin and oral birth control (barrier contraception must be used during the therapy);
- The metabolism and thus a rapid exertion of the medication from the body are induced by the intake of Barbiturates, carbamazepine, diphenylhydantoin, primidone, and alcohol.
If you take any medications and are unsure whether they are included in some of these classes, consult a doctor first.
Precautions
The medication must be cautiously used by people with impaired liver function or people who take hepatotoxic medicines.
The action of the medication can lead to the increase in the blood levels of urea.
The medication can cause sensitivity to sunlight that can result in sunburns. Thus, it is recommended to avoid sun exposure during the therapy and within the following 4-5 days.
The use of antibiotics can cause the excessive growth of insensitive microorganisms, particularly fungi, including Candida, and the development of superinfection. This requires the withdrawal of the antibiotic and the adoption of appropriate measures.
The use of the antibiotic during the first trimester of pregnancy and during the first year of life of an infant can cause irreversible teeth structure and color changes.
Where can you buy Doxycycline?
Order Doxycycline from our med store to save on the therapy. We sell the qualitative generics that are not less effective than the branded drugs but cost less money.
Doxycycline shipping
We ship all of the products we offer internationally via standard (up to 25 days) and express (up to 14 days) mail.
Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.
Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.
For more answers see the FAQ section
|