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4RX Store > Medication List > Antibiotics drugs > Order Rifadin online

Antibiotics Medication (Rifadin)

 
Generic name:
Rifadin
Brand name:
Rifampin
Description:
Rifadin is a branded medication based on Rifampin. Under the less known names, the same formulation is sold and it can be found under as generic Rifadin. The formulation is used for the treatment of tuberculosis of different location, i.e. bones, lungs, etc., leprosy, severe staphylococcus infection resistant to other antibiotics, and so on. There are alternative ways of using this medication and combinations of this drug with others. To find out the useful information read the full guide below.
Indications:
Different types of tuberculosis, Lung tuberculosis, Bone tuberculosis, Leprosy, Infectious diseases of non-tuberculosis nature caused by the sensitive pathogens, Severe staphylococcal infection, Legionellosis, Brucellosis, Prophylaxis of meningococcal meningitis
Benefits:
The medication effectively treats tuberculosis and other diseases caused by the sensitive pathogens
Manufacture:
Lupin Pharmaceuticals Inc.
Lupin Pharmaceuticals Inc.
Synonyms:
Archidyn, Rfamipicin, Rifagen, Rifaldazin, Rifaldin, Rifampicin, Rifamycin, Rifaprodin, Rifoldin, Riforal, Rimactan, Rimactin, Rimazid, Rofact, Tubocin
 
   
Rifadin (Generic Rifampin)
 
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Order Generic Rifampin Buy Rifadin 150mg

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  Generic Medication guide:

What is the medication sold under the name Rifadin? When is it used?

The brand Rifadin is a property of the French pharmaceutical concern Sanofi Aventis. The active ingredient of the medication sold under this brand is Rifampin, an antibiotic with pronounced anti-tuberculosis effect. The formulation was developed back in 1965 and is still widely used for the treatment of various forms of tuberculosis, i.e. lung tuberculosis or with the foci in other body parts, leprosy, gram-positive (especially staphylococcus) and gram-negative (meningococci, gonococci) pathogens. As since the creation of the medication more than 50 years had passed, for a long time already the formula can be used by basically all manufacturers of medications. This makes the formulation more accessible in a form of generic. For instance, if you need to buy Rifadin you can opt for a medication based on Rifampin but called differently and at a lower price. To find such medicines, you should look for generic Rifadin.

The mechanism of the medication effect is related to the suppression of the DNA synthesis of the susceptible (sensitive) microorganisms. The treatment with Rifadin is prescribed in:
- Tuberculosis of different localization, i.e. lung tuberculosis, bone tuberculosis, tuberculous meningitis, as well as atypical mycobacteriosis;
- Infectious diseases of non-tuberculosis nature caused by the pathogens sensitive to the medication including severe forms of staphylococcal infection, leprosy, legionellosis, brucellosis;
- Prophylaxis of Meningococcal meningitis in people who had a close contact with the carriers;
- Symptomless carrying of Neisseria meningitides.

Worth noting that the formulation is always used as a part of the combination therapy so it’s never enough to buy generic Rifadin and use only these pills. You need to get a precise diagnosis and a list of drugs you need with the directions on how to use it from your doctor. For instance, leprosy is treated with the use of the antibiotic and dapsone; brucellosis - with antibiotics from the group of tetracyclines (for instance, Doxycycline). The other drugs for the therapy can also be bought from our med store without Rx. If you cannot find one or another medication, please contact our customer support managers and they will gladly help you.

Rifadin contraindications

For the tablets of the medication the following conditions are considered contraindications:
- Hypersensitivity to Rifampin, other medicines from the same class or other ingredients of the medication;
- Severe liver or kidney failure;
- Jaundice caused by bile stasis;
- Infectious hepatitis carried in less than a year before the therapy with this drug;
- Severe pulmonary heart disease;
- Simultaneous use with Saquinavir/Ritonavir.

Please note that for other forms of the medication that are injected there are more contraindications, for instance, age under one year, alcoholism, and others. For a safe therapy, you must undergo a comprehensive checkup and follow your doctor’s instructions.

Use of Rifadin during pregnancy

You must not buy Rifampin and use it while being pregnant as the drug is completely prohibited to be taken during the first three months of pregnancy and may be used during the next months only at doctors’ discretion if they believe that the benefits would be higher than the risks to the baby.

Rifadin dosing

The pills are taken orally a half an hour before or two hours after a meal with an at least a half of glass of water.

Tuberculosis:
- Adults are appointed from 8 to 12 mg per kg of the body weight a day. Patients with the body mass fewer than 50 kilograms (110 lbs) are given 450 mg a day and those who weight over 50 kg (110 lbs) – 600 mg a day.
- Kids aged from six to twelve are given 10-20 mg per kg of the body weight. The highest possible daily dosage is 600 mg.
The duration of the course is individual and is chosen on the basis of the therapeutic effect and can be from one year and more. To avoid the resistance of bacteria, the formulation is used along with other anti-tuberculosis medications of I and II rows in the regular dosages.

Infectious and inflammatory diseases of non-tuberculosis nature caused by drug-susceptible pathogens - brucellosis, legionellosis, severe forms of staphylococcal infection (along with other appropriate antibiotics to prevent the emergence of resistant strains):
- Adults are appointed 900-1200 mg a day split into two-three intakes. The highest daily dosage is 1200 mg. After the disappearance of symptoms, the formulation must be used for two-three more days.
- Leprosy is treated with the use of the formulation and immune-stimulating medications. The medication is appointed in the dosage of 600 mg a day split into one-two intakes during three to six months. If necessary, repeated courses can be implemented with an interval of one month. Alternatively, the medication can be used by 450 mg split into three intakes and taken for two-three weeks with an interval of 2-3 months for one to two years.
- N. meningitides carriage requires the use of the medication for four days. The daily dosage for adults is 600 mg, for children it is 10-12 mg per kilogram of the body weight.

Dosage adjustments

In liver function impairment, the daily dosage must not exceed 8 mg per kilogram of the body weight.
- The daily dosage for elderly patients is chosen based on their kidney function. If the kidney function is impaired, the dosages are lowered respectively as the liver takes the part of the work if kidneys are not managing the excretion. It is not advised to use the medication in senior patients if they have liver dysfunction.

Rifadin overdose

The symptoms of an overdose include nausea, vomiting, pain in the abdomen, fatigue, sleepiness, allergic reactions, fever, wheezing, jaundice, rapid heart rate, low blood pressure, and others.
The treatment is made of discontinuation of the formulation use, gastric lavage during the first two-three hours after an overdose, intake of activated carbon, and symptomatic therapy. In severe cases, forced diuresis and hemodialysis can be performed.

Rifadin adverse effects

When you buy generic Rifampin and start the therapy you can develop the following negative symptoms:
- Nausea, diarrhea, heartburn, indigestion, discomfort in the abdomen, bloating, esophagitis, colitis, erosive gastritis, low appetite, and intestinal dysbiosis.
- Temporary liver indices violated, jaundice, hepatitis, bile stasis, and other symptoms of liver dysfunction.
- Blood disorders, low hemoglobin, purpura, cerebral hemorrhage.
- Headache, vertigo, fatigue, asthenia, confusion, muscle weakness, generalized numbness, psychoses.
- Lowered blood pressure, wheezing, bronchospasm, skin rash and itching, and other hypersensitivity reactions including anaphylaxis.
- Kidney dysfunction, menstrual cycle violation, swelling of the face and limbs, and others.

These or other adverse effects may develop and may not develop. The likelihood of their development commonly depends on the already existing conditions, for instance, liver diseases, or predisposition to the development of allergic reactions.

Adverse effects in percentage

Adverse effects by body systems during first 2 months of trial
Number of patients with adverse events
(In total 122 patients)
Cutaneous (rash, erythroderma, erythema, exfoliative dermatitis, Lyell syndrome, urticaria, localized skin rash, diffuse skin rash, pruritus, generalized hypersensitivity)
21 (17%)
Gastrointestinal (nausea, vomiting, digestive pain, diarrhea)
14 (11%)
Musculoskeletal (arthralgia, long bones pain, phlebitis, localized joint pain, diffuse joint pain, edema of the legs)
8 (7%)
Cutaneous (rash, erythroderma, erythema, exfoliative dermatitis, Lyell syndrome, urticaria, localized skin rash, diffuse skin rash, pruritus, generalized hypersensitivity)
6 (5%)
Gastrointestinal (nausea, vomiting, digestive pain, diarrhea)
2 (2%)
Musculoskeletal (arthralgia, long bones pain, phlebitis, localized joint pain, diffuse joint pain, edema of the legs)
4 (3%)
Hearing and Vestibular (tinnitus, vertigo, vertigo with loss of equilibrium)
4 (3%)
Liver and Biliary (hepatitis with conjunctival jaundice, hepatitis with deep jaundice)
3 (2%)
Central and Peripheral Nervous System (sweating, headache, insomnia, diffuse paresthesia of the legs, anxiety, diabetic coma)
43
Rifadin interactions

The formulation is a potent inducer of P450 cytochrome which can cause potentially harmful interactions. Thus, before you order Rifadin, inform your doctor about all other medications that you use.
For instance, it is contraindicated to use it along with Saquinavir/Ritonavir.
Rifadin diminishes the effect of indirect anticoagulants, corticosteroids, oral hypoglycemic medicines, antiarrhythmic medications, benzodiazepines, oral contraceptives, and other hormones, and others (see the full list in the package insert).
Antacids prevent the formulation of normal absorption and thus make it less effective.
In the simultaneous use with opiates, anticholinergics, and ketoconazole, the bioavailability of the medication substantially drops.
The level of the medication in the blood plasma is elevated in the same time use with Probenecid and co-trimoxazole.
The likelihood of severe liver dysfunctions rises in the simultaneous use of the antibiotic with Isoniazid or Pyrazinamide.
These are not all interactions. To find out about all of them, read the package insert or consult your physician.

Rifadin precautions

For the non-tuberculosis diseases, the antibiotic is appointed only if the first choice antibiotics are ineffective.
Individuals with kidney dysfunction require the dosage adjustments if the dosage is above 600 mg a day.
The antibiotic must be cautiously used in newborn or prematurely born babies and in weakened patients. Newborns need also to be given vitamin K as a prophylaxis of bleedings.
Rifadin must be cautiously used in HIV patients.
In flu-like syndrome development during the intermittent therapy, it is recommended to shift to the daily medication intake with the gradual dosage increase.
During the therapy, regular tests of the blood, liver and kidney function must be made.
In case the medication is appointed for the carriers of Neisseria meningitides, it is necessary to perform a strict observance over the patient to timely notice the symptoms occurrence if the resistance develops.
The formulations that lower the absorption of the medication (for instance, antacids) must be taken no sooner than four hours after Rifadin.
During the therapy, it is encouraged to refrain from alcohol use to minimize the drug’s negative effect on the liver.

Where can you buy Rifadin?

You can order generic Rifadin and other medications used for the therapy of tuberculosis or other diseases treated with the formulation at our med store at the low prices.

Rifadin shipping

We ship all medicines we offer our clients to buy all over the world. The standard shipping takes up to 25 days and standard only up to 7. You can enjoy free shipping when ordering for $170 or more.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

For more answers see the FAQ section

 

 
 
   
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