Generic Medication guide:
People diagnosed with hepatitis C or other serious viral infections are facing a tough decision: to spend a fortune on the expensive modern medications or use cheaper outdated treatment methods. Though today advanced drugs without any side effects and a short but super effective treatment course, such as Sofosbuvir, are available, their price is unaffordable for millions of people who need it. In 2016, the cost of the 12-week treatment course with this innovative medication in the U.S. is around 90.000 Dollars. In other developed countries, the situation is also deplorable.
Social activists protest against the incredibly high cost of the treatment and demand the owner of the original medication brand to lower the unreasonably expensive price. They blame the company in greediness and inhumanity because statistically, namely people with lower incomes due to the lower level of life are susceptible to hepatitis C development. 91% of all people in the world infected with the hepatitis C reside in the developing or underdeveloped countries.
Fortunately for them and for people in America who cannot pay for the treatment course based on the brand-name medication, the manufacturer of Sofosbuvir allowed other pharmaceutical companies to use the formula and sell their own versions of the drug cheaper. To get the drug, you need to buy Generic Sofosbuvir (Hepcvir). But you need to remember that it is not sold in America. In order to get the medication, you should choose a reliable online pharmacy like ours to buy the drug abroad and receive it without any trouble in the U.S.
History of Generic Sofosbuvir (Hepcinat)
The new generation medication Sofosbuvir was first presented to the public in 2007. It was discovered by a chemist Michael J. Sofia who worked for Princeton-based pharmaceutical company Pharmasset. The first clinical trials of the medication in people were conducted in 2010. After overwhelming results were announced, a biopharmaceutical giant Gilead Sciences offered the company acquisition for $11 billion. After the acquisition of the company-developer of the medication, Gilead applied to the FDA with the substance Sofosbuvir. Based on the clinical trials’ results presented by the manufacturer, the Food and Drug Administration granted the medication an expedited review which is usually granted only for the medications that may offer big treatment advantages over existing options for people with serious or life-threatening diseases.
The medication was approved as an independent treatment in 2013 and in 2014 in the composition of the fixed dose combination drug Sofosbuvir/Ledipasvir. Both treatments were also granted Breakthrough status. The substance was also promptly added to the List of Essential Medicines by the World Health Organization.
Since the beginning of 2016, you can buy Generic Sofosbuvir (Hepcvir or Hepcinat). The medication is now available in a form of generic medications made by several licensed drug manufacturers located in India. The great advantage of Generic Sofosbuvir is that it costs much cheaper. Though activists still are unsatisfied with the high price of even generic versions of the medication, there is still a great difference between the brand-name medication and generics’ price. For example, the treatment cost with the brand medication is around 90.000 dollars while Generic Sofosbuvir is available for only 2600 Dollars.
When Sofosbuvir (Hepcinat) is used?
The medication is primarily used for the treatment of hepatitis C though further research of its effectiveness in other conditions is still in process.
The drug is used in combination with interferon, Ribavirin, and other antiviral medications depending on the genotype of the hepatitis C virus and the history of the treatment of a particular patient. Worth noting that now you can buy Generic Sofosbuvir (Hepcvir) or Generic Sofosbuvir with Ledipasvir which is sold under a trade name Hepcivir-L that is a fixed dosage combination drug. But before you make the purchase, you need to get the precise directions from your doctor on the combination of the medications and the dosage to order the right one suitable namely for your case.
How does Generic Sofosbuvir (Hepcinat) medication act?
The medication damages the virus RNA and prevents it from replication. The rest, killing of the existing cells, is made by the patient’s own immunity. The effect is achieved through the inhibition of HCV NS5B RNA-dependent RNA polymerase needed for virus spread and replication.
The medication you receive when you buy Generic Sofosbuvir (Hepcvir) is a prodrug, i.e. a medication that transforms into an active agent after it is metabolized in the body. The active substance that is created as a result of the drug transformation is called uridine analog triphosphate that terminates the chains in the virus RNA.
Is there a difference between the brand-name medication and generic?
Though some doctors may be advocating brand drugs over generics, the official point of view is that generic medications approved by the original drug developer are identical to the expensive brand drugs. You may think that there is no reason for the expensive brand drug owners to give licenses to other pharmaceutical companies to allow them make the same drugs cheaper but in fact, they are obliged by the law.
Moreover, such drugs, generics, are mostly created for developing countries where people literally cannot afford expensive treatment but to protect and support their human rights, the World Health Organization created the term generics and strictly supervises the medications compliance with the original formulations. Therefore, you should not worry that you will get an inferior medication when you buy Generic Sofosbuvir (Hepcvir). The drug is as effective and safe as the brand-name medication regardless of its cheaper price.
How Generic Sofosbuvir (Hepcvir) should be used?
The standard dosage for adults is 400 mg (one pill) a day. Nevertheless, you should consult your doctor first before taking the medication in case you need a dosage adjustment and to find out what other medications your therapy must include for the best and fast results.
Whom the drug is contraindicated?
The drug is considered quite safe and is not contraindicated to anyone except pregnant and breastfeeding women because the drugs it is used in combination with can damage the fetus and baby. Before you start the therapy, you need to inform your doctor about all conditions you have to help your doctor decide on the right medications with which you would need to use Hepcvir.
Can Generic Sofosbuvir (Hepcvir) be used during pregnancy?
The drug itself is not harmful for the fetus and the baby but the medications it is combined with can lead to serious birth defects and even death of the baby. Therefore, it is recommended not to undergo the therapy while pregnant or breastfeeding.
What side effects can th drug cause?
The medication is quite safe and does not cause any adverse reactions if used alone. However, as it is in most cases used in combination with other medications, the additional drugs can cause a variety of side effects such as a headache, increased fatigue, rash, flu-like symptoms, and others.
Where can you buy Generic Sofosbuvir (Hepcvir)?
Currently, you can buy the medication only from the drugstores situated abroad. It is a legal practice and you can purchase the drug even without a prescription and get it at your doorstep. Check the analogs of the medication we sell and choose the right generic based on your doctor instructions.
Interactions with other medications
The negative interactions with Sofosbuvir occur when the combination therapy with other drugs is used. For example, with ledipasvir, daclatasvir, and simeprevir, it can lead to the life-threatening low heart rate when amiodarone is also used.
The absorption of the medication in the intestines is reduced by Rifampicin and other medications that induce intestinal P-glycoprotein.
Certain HIV protease inhibitors and anticonvulsants diminish Sofosbuvir concentration also reducing its effect.
Remember that hepatitis C is easily transferred through an unprotected sexual intercourse. It means that you need to inform your partner or partners and get them checked as well as use condoms and avoid getting pregnant while the virus is still active.
Our doctor prescribes online for free, and there is no doctor’s consultation fee.
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.
For more answers see the FAQ section