What is Adalat and when is it used?

Adalat is a brand of an antihypertensive medication produced by the German pharmaceutical concern Bayer. The active agent of the product is called Nifedipine. It is so-called unpatented name or name of the active agent. This name can be found under a trademark of the drugs that are based on it. The formula for the medication was developed back in the 1970s so it is no longer exclusively used by Bayer but also for a variety of pharmaceutical companies from all around the world.
Your healthcare provider can tell you to buy Adalat to manage arterial pressure in hypertension, and/or treat ischemic heart diseases such as chronic stable angina, and vasospastic angina (Prinzmetal angina).
You can get the formulation without Rx from our med store which basically means that if you see your diagnosis on the list of indications for the use you can get the pills and start using them without consulting your doctor. But please keep in mind that there are a variety of medications for the treatment of the same conditions for a reason. Only a healthcare specialist can choose you the best treatment plan based on your medical history, allergies, and so on.

Adalat contraindications for use

- Increased sensitivity to Nifedipine or any other component of the pills or other dihydropyridines;
- Cardiogenic shock
- Severe aortic stenosis;
- Porphyria;
- Recent myocardial infarction (one month or less after its occurrence);
- Concurrent use of Rifampicin due to the inability to reach the effective level of the antihypertensive drug due to the induction of the enzymes by Rifampicin;
- Unstable angina;
- Inflammatory diseases of the bowel or Crohn’s disease.
It is also not recommended for anyone younger than 18 years as its safety and effectiveness in this group of patients isn’t confirmed.

Use of Adalat during pregnancy and breastfeeding

Pregnant and breastfeeding women must not buy generic Adalat and use the formulation because it is proven that it’s not safe for a fetus or a baby.

Adalat dosing

It is preferable that the dosage is chosen individually by an attending doctor who knows your medical history. Such factors as the severity of the condition, age of the patient, the presence of chronic diseases, and response to the treatment must be taken into account.
Some patients may require the use of the lowest dosages at the beginning of the therapy with a gradual increase.
Patients with liver dysfunction may need a thorough monitoring of their condition and if adverse effects develop – the lowering of the dosage and even the discontinuation of the treatment.
- The treatment of ischemic heart disease is made with one 20 mg pill or two 10 mg pills two times a day. Thus, the daily dosage is 40 mg. If higher daily dosages are advised, the daily dosage must be gradually elevated to 60 mg.
- Hypertension treatment is made with one 20 mg pill or two 10 mg pills two times a day. Thus, the daily dosage is 40 mg.
If when you buy Nifedipine you also use inhibitors or inducers of the CYP3A4 enzyme, you may require dosage adjustment of the antihypertensive medication or even its exchange for another medication.
The medication has a pronounced anti-ischemic and antihypertensive effect so it must be withdrawn gradually especially in the use of high dosages to avoid a sharp aggravation of the condition.
The tablets must be swallowed without crushing and washed down with a small amount of water. They can be taken without regard to meals.
It is recommended not to drink grapefruit juice while undergoing the therapy with the drug.
The recommended interval between the tablets use is not less than six hours. Preferably, it should be twelve hours.

Adalat overdose

In an overdose with the medication, you can develop a headache, reddening of the face, prolonged hypotension, and lack of pulse in peripheral arteries. In severe cases, there is tachycardia or bradycardia, impaired sinus node function, slowing down of atrioventricular conduction, hyperglycemia, metabolic acidosis and hypoxia, collapse with loss of consciousness and cardiogenic shock accompanied by lung swelling, impaired consciousness up to coma.
The measures to cope with are first of all aimed to wash out the excess of the medication from the body. The treatment should be made at a hospital so that medical professionals would be able to monitor the vital functions and render symptomatic treatment including the possible use of an artificial pacemaker.

Adalat adverse effects

When you buy generic Nifedipine you can encounter such unpleasant effects as:
- Tachycardia at the beginning of therapy in patients with angina pectoris, an increase in the frequency, duration of seizures, or an increase in the severity of symptoms, cases of asymptomatic myocardial ischemia, exacerbation of myocardial ischemia, cardiac conduction disturbance, chest pain.
- Thrombocytopenia, anemia, leukopenia, aplastic anemia, agranulocytosis;
- Headache, vertigo, fatigue, paresthesia, irritability, sleep disorders (insomnia, drowsiness, restless sleep), depression, tremor, loss of coordination of movements, migraine, loss of consciousness, noise in the ears.
- Temporary blindness, temporary retinal ischemia, excessive tearing, reduced visual acuity, eye pain.
- Dyspnea, nosebleeds; upper respiratory tract infections, cough and nasal congestion; angioedema.
- Constipation, diarrhea, nausea, abdominal pain, dry mouth, bloating, vomiting, gums reddening; black stools, heartburn, taste disturbances, dysphagia, intestinal obstruction, intestinal ulcer, insufficiency of the gastroesophageal sphincter.
- Polyuria, nocturia; dysuria.
- Rash, itching, redness, erythema of the cheeks (facial flushing) urticaria, excessive sweating, chills purpura, gingival hyperplasia, Stevens - Johnson syndrome, exfoliative dermatitis, erythema polymorphic, photosensitivity reaction, and hair loss.
- Allergic reactions, angioedema, rash, and anaphylaxis.
- Backache, myalgia, swelling of the joints gout, arthralgia, arthritis, and muscle cramps.
- Hyperglycemia (especially in patients with diabetes mellitus), weight gain;
- Swelling of the feet, ankles or legs, arterial hypotension.

Adalat interactions

- Nitrates, beta blockers, diuretics, tricyclic antidepressants, fentanyl, and alcohol enhance the blood-pressure-lowering effect.
- The medication increases the activity of Theophylline and reduces renal clearance of Digoxin.
- It slows down the washing out of vincristine and enhances its adverse effects.
- Adalat increases the bioavailability of cephalosporins (Cefixime).
- Cimetidine and ranitidine (to a lesser extent) can increase the plasma levels of the antihypertensive medication.
- Diltiazem slows down the metabolism of the formulation so the lowering of the dose of Nifedipine is required.
- The medication is incompatible with Rifampicin as its washing out is accelerated.
- Grapefruit juice increases the medication’s bioavailability.

Please note that this is not the whole list of interactions so if you take any medications or plan on taking them, read the full package insert and consult your doctor before you order Adalat.

Where can you buy Adalat?

Our med store offers you the best prices for the highest quality generic medications that are n way inferior to the branded ones. You can order generic Adalat at this webpage and enjoy the optimal effect at a fraction of the branded drug price.

Adalat shipping

We will ship your order any country of the world including the UK, Canada, Australia, U.S., and so on.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

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