Generic Medication guide:
What is Atacand and when is it utilized?
Atacand is one of the trade names of Candesartan owned by the English-Swedish pharmaceutical company AstraZeneca.
The formulation is a selective suppressor of angiotensin II receptor which is the principal hormone that has a primary role in arterial blood elevation, congestive heart failure, and other heart or vascular diseases onset. The primary actions of the hormone include the constriction of the vessels, promotion of aldosterone release, water-electrolyte balancing, and promotion of cell increase. They are intermediated by the interworking of angiotensin II with the receptors. Unlike ACE inhibitors, Atacand doesn’t inhibit the angiotensin-converting enzyme. Thanks to that, people who use it instead of ACE inhibitors less frequently develop coughing. As a result of blocking AT1 receptors, the elevation of renin, angiotensin I, angiotensin II and a lowering in plasma aldosterone level occurs.
The medication is advised for extended and mild blood pressure lowering without sharp decreases or fluctuations of the arterial pressure. You can buy Atacand without Rx if you are appointed an antihypertensive therapy but you should better consult a doctor first.
The precise indications for the use of the pills are:
- Therapy of elevated arterial pressure;
- Therapy of heart failure and violated left ventricular systolic function as an addition.
How fast does the medication act?
The beginning of the action of the medication is usually happening within two hours after a dosage intake. When the medication is used daily, the most potent lowering of the daily arterial pressure is obtained within four weeks of uninterrupted use. The single dosage of the formulation a day renders effective and smooth lowering in arterial pressure over a day and a night with mild swings in the pressure in the breaks between taking the next dosage.
The effectiveness of the medication isn’t contingent on the user’s age and sex.
Atacand contraindications for use
Even though the formulation has a number of advantages in comparison with ACE inhibitors, in some cases it can be forbidden to be utilized:
- In increased sensitivity to Candesartan or supporting substances of the pills;
- In severe dysfunction of liver and/or bile stasis;
- During pregnancy and breastfeeding a baby.
You can buy generic Atacand and use it but only if your doctor approves in:
- Pronounced kidney failure;
- Both kidneys artery stenosis;
- Mitral valve stenosis;
- Kidney transplant;
- Brain blood circulation diseases and ischemic heart disease;
- In the lowered volume of blood;
- Primary hyperaldosteronism;
- Hypertrophic cardiomyopathy;
- Age below 18 years.
The advised starting and supporting dosage of the formulation is 8 mg taken once a day. In the majority of cases, the stable blood-pressure-lowering action is observed within four weeks.
In some individuals in whom the arterial pressure isn’t sufficiently controlled by the regular dosage, the daily use of Atacand can be raised to 16 or even 32 mg a day. Alternatively, regular dosages with the addition of other antihypertensive formulations to the therapy can be taken. But please consult your healthcare provider before you buy Candesartan especially if you want to combine it with other medications or use higher than regular dosages.
Dosage adjustments for special groups of individuals
- Elderly patients do not require dosage adjustments;
- Patients with a low volume of circulating blood possibly due to dehydration can start to take the formulation from the dosage of 4 mg a day.
-Individuals with kidney function impairment, including on hemodialysis, must start the use from 4 mg day. The use of higher dosages must be discussed with a doctor.
-Individuals with liver dysfunction of mild to moderate severity are advised to start the therapy with 4 mg once a day. The dosage can be adjusted based on the individual’s response to the therapy. Individuals with severe liver dysfunction are prohibited to use the formulation.
Since the medication lowers the pressure smoothly and gradually, severe adverse reactions even in significant overdose are unlikely. The presumable adverse effects that can develop are substantial lowering in arterial pressure and lightheadedness. The treatment required is aimed at the minimization for the symptoms. A patient should be put on the bed with the lift of the head of the bed.
Atacand adverse effects
The adverse effects observed at the time of the clinical trials of the formulation were mild and quickly fading and not much more often than in the placebo group. The general frequency of adverse reactions development didn’t depend on the dosage of the medication and age of the patient. The described below adverse effects were recorded at least by 1% more often than in the placebo users. Thus, when you buy generic Candesartan be ready that you can develop certain unpleasant effects from the formulation use:
- Dizziness, weakness, headache;
- Respiratory infections.
- Pronounced arterial pressure lowering;
- Kidney function impairment;
- High creatinine, urea, and potassium identified through laboratory tests.
During clinical research, the combinations of the medication with digoxin, oral birth control pills, glibenclamide, Nifedipine, and other formulations that can interact with other medicines, were studied and no substantial interactions identified.
The simultaneous use of Atacand with other antihypertensive medications enhances its antihypertensive effect.
The concurrent therapy with the formulation and diuretics that do not wash out potassium, potassium-including medications, and other substances that can elevate the level of potassium in the blood can cause hyperkalemia.
If the medication is taken along with Lithium, it is advised to control the latter’s level in the blood as when used with ACE inhibitors its level in the blood is raised and the negative effects enhanced.
If you use any other medications when you plan to order Atacand, consult a healthcare specialist first.
The use of the formulation can promote the worsening of the kidney function.
In the use of Atacand in individuals with arterial high pressure and pronounced kidney failure, the frequent control over the potassium and creatinine levels in the blood is required.
Individuals with chronic heart failure when utilizing the medication need regular control over the kidney function especially if they are over 75 years old or already have kidney failure.
Where can you buy Atacand?
The cheapest way to get the medication is to order generic Atacand from our pharmacy. Generics are absolutely identical to the branded drugs when they are made by reliable manufacturers but cost several times less money.
We will ship Atacand to any country including the U.S., UK, Australia, Canada, and so on within from 7 to 25 days based on the delivery type chosen.
Our doctor prescribes online for free, and there is no doctor’s consultation fee.
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.
For more answers see the FAQ section