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4RX Store > Medication List > Blood Pressure drugs > Order Hyzaar online

Blood Pressure Medication (Hyzaar)

Generic name:
Brand name:
Losartan + Hydrochlorothiazide
Hyzaar is a combined formulation based on Losartan and Hydrochlorothiazide. Both of the active substances render antihypertensive effect (i.e. blood-tension-lowering) but through different mechanisms. The combination enhances effects of both of them which contribute to the more effective blood pressure lowering in patients for whom the single medication is not sufficient. The formulation is used for arterial hypertension and the prevention of stroke and myocardial infarction in patients with elevated blood pressure. Find out how to use the medication from our guide below.
Arterial hypertension, Arterial high pressure, High blood pressure, Prevention of stroke, Prevention of myocardial infarction
The medication effectively lowers blood pressure in patients for whom a single medication is not enough and prevents stroke, myocardial infarction, and other cardiovascular complications
Ranbaxy Pharmaceuticals
Ranbaxy Pharmaceuticals
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Hyzaar (Generic Losartan + Hydrochlorothiazide)
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Order Generic Losartan + Hydrochlorothiazide Buy Hyzaar 12.5mg


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  60 tabs
$36.65 ($50.64)








  80 tabs
$43.97 ($59.55)








  100 tabs
$53.45 ($78.44)








  120 tabs
$63.95 ($91.06)








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  Generic Medication guide:

What is the medication marketed as Hyzaar?

Hyzaar is one of the medicinal brands of an American pharmaceutical giant Merck. The medication sold under this name is based on two active agents, Losartan and Hydrochlorothiazide. These substances are used together or separately in different medications and are sold under a variety of names because they are no longer covered by an exclusive patent of the developer. This means that when your cardiologist tells you to buy Hyzaar you can seek for a generic version of the medication, i.e. the same formulation sold under other names because it’s made by a different company.

How does Hyzaar act and when is it prescribed?

This combined formulation renders a synergic action in diminishing of arterial tension. It is presumed that the action is due to the additive action of both ingredients. Besides, the diuresis action of Hydrochlorothiazide enhances the activity of renin, aldosterone secretion, reduces potassium in the body and elevates the content of angiotensin II. Losartan suppresses all significant actions of angiotensin II that is liable for vessels narrowing and lowers the loss of potassium caused by diuretic use through the suppression of aldosterone.
The tension-lowering effect from the combined medication use is maintained within 24 hours and although it significantly lowers the arterial tension, it doesn’t significantly influence the heartbeat rate.

You can buy generic Hyzaar for:
- Arterial hypertension that cannot be controlled by a single medication;
- Lowering of cardiovascular risk in arterial tension and left ventricular hypertrophy, lowering of myocardial infarction and stroke.

You can get the formulation without showing us Rx from your doctor but we highly advise you to consult a specialist who knows your medical record to be sure that you are given the optimal treatment.

Contraindications for Hyzaar use

The formulation use is forbidden when it can do more harm than good:
- In increased sensitivity to its components or sulfonamide derivatives;
- In inability to urinate due to any reason;
- In severe kidney or liver work impairment;
- When a patient with diabetes uses Aliskiren;
- When expecting a baby and breastfeeding;
- In anyone aged less than eighteen;
- Lactose intolerance, lactase deficiency, glucose-galactose malabsorption syndrome.

Hyzaar can be used but only if a qualified specialist approves in:
- Water-electrolyte disequilibrium of the blood, for instance, caused by diarrhea or vomiting;
- In kidney failure of moderate severity;
- In kidney artery stenosis;
- In diabetes;
- In hypercalcemia, hyperuricemia, and/or gout;
- In the history of severe allergic reactions or asthma;
- In systemic diseases of connective tissue;
- Hypovolemia;
- During the therapy with NSAIDs.

Hyzaar dosages

When you buy Losartan + Hydrochlorothiazide, consult your attending physician to know the exact dosing regimen suitable namely for you. We offer the data from the official instruction but it’s better to follow your physician’s recommendations over them.
The pills can be taken with or without food. The prescribed dosage is taken once a day. Contingent on the severity of arterial hypertension, a single dosage can be or two tablets. If this dosage is insufficient, an alternative medication or forte version of Hyzaar is appointed.
The maximum hypotensive effect is achieved within three weeks after the course start. The effectiveness doesn’t depend on age and sex of a patient.

Hyzaar overdose

There are limited data on an overdose with the formulation. The most probable symptoms are a drop in the arterial tension, tachycardia (fast heartbeat), and dehydration. The treatment is symptomatic. It includes the correction of water and electrolytes balance, blood tension and liver function if it is impaired.
The use of the medication must be discontinued and gastric lavage performed if the excessive dosage had been taken not long ago.

Hyzaar adverse effects

The medication is generally well tolerated. In the majority of cases, the negative reactions are quickly fading and do not require the discontinuation of Hyzaar use. The probable negative effects that can develop as a response to its use include the effects caused separately by Losartan and Hydrochlorothiazide. There are no additional negative effects resulting from the substances combinations.
According to the clinical trials for arterial tension management, lightheadedness was the only negative effect the frequency of which in Hyzaar use exceeded the frequency of it in the placebo group by 1%.
As for the use of the formulation as a prophylaxis of infarction or stroke, the most usual adverse effects that were reported by 1% more individuals than in placebo were lightheadedness and general weakness.
The other possible negative reactions that you can develop when you buy Losartan + Hydrochlorothiazide are:
- Blood composition disorders;
- Anaphylaxis, angioedema (≥0.01% and<0.1% of cases);
- Loss of appetite, dyspepsia, abdominal pain, esophageal reflux, gastrointestinal colic, stool disorder, nausea, pancreatitis, hepatitis, jaundice, and others.
- Sleeplessness, anxiety, headache, migraine;
- Temporary vision impairment;
- Tachycardia;
- Cough, nasal congestion, pharyngitis, sinusitis, respiratory tract infections, adult respiratory distress syndrome.
- Rash, urticaria, erythroderma, photosensitivity, lupus-like syndrome;
- Myalgia, muscle pain, arthralgia.
- Glucosuria, renal function impairment, renal failure;
- Low sex drive, erectile dysfunction.
The likelihood of the listed adverse effects is minimal but it can be higher in patients with predisposing factors, for instance, with digestive or kidney disorders.

Hyzaar interactions

When you order Hyzaar, make sure to check with your physician that you don’t use or plan to use any medications that will make the effect of the formulation lower or harmful.
- The formulation is compatible with other antihypertensive medications if additional blood-tension lowering is needed;
- The risk of postural hypotension is higher in use of alcohol, barbiturates, and narcotic analgesics.
- Hypokalemia and loss of electrolytes are possible in use of corticosteroids.
- The formulation enhances the effect of anti-depolarizing muscle relaxants, and lithium toxicity; it lowers the effect of adrenergic agonist;
- Cholestyramine and colestipol lower the absorption of the formulation in the digestive tract, and NSAIDs can reduce the formulation’s effects.

Hyzaar precautions

Individuals with a history of angioedema must use the first dosages of the formulation under a medical supervision.
In patients with a decrease in circulating blood volume and/or low sodium in the blood resulting from overuse of water pills or low-salt diet, diarrhea or vomiting, the development of postural hypotension (a sharp drop of blood pressure standing up) can occur with the first dosage intake. Thus, these conditions must be corrected before the course with Hyzaar begins.
Water-electrolytes imbalance can develop in individuals with kidney function impairment. They must be monitored for potassium content in the blood and creatinine level. It is especially important for individuals with congestive heart failure and cc 30-50 ml per minute. To avoid the development of such negative reactions, the use of the formulation must not be combined with any medications or additives that elevate potassium level.
Patients with impaired liver function and particularly with liver cirrhosis can have an elevated content of the formulation in the blood. Thus, the formulation use is prohibited in severe liver dysfunction and must be cautiously used in mild to moderate dysfunction.

Where can you buy Hyzaar?

The prices of the branded and generic medications differ significantly while their composition is the same. Besides, regular drugstores, in general, sell the medications at higher prices than online pharmacies. Therefore, if you want to save, order generic Hyzaar from our online pharmacy and get the highest quality for a fraction of price.

Hyzaar shipping

This medication, as well as all others that we sell, is shipped internationally via standard and express shipping in 7-25 days respectively. You can buy pills for $170 or more per one order and enjoy free shipping.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

For more answers see the FAQ section


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