Generic Medication guide:
What is the product sold as Lozol and when is it appointed?
Under the name Lozol, you can buy a medicinal substance called Indapamide. It is a water pill that contributes to the dilation of the vessels and therefore diminishing of the blood tension.
The formulation can be also bought under other names if you opt for a different manufacturer. It is beneficial to get a medication with a less known name as it can be substantially cheaper while having the same composition.
The use of the medication is appointed in diagnosed essential arterial hypertension, i.e. a chronic disease characterized by a prolonged and persistent elevation in arterial tension, the diagnosis of which is made by eliminating all secondary hypertension possibilities. It can be also utilized to lower swelling due to heart failure.
Please note that you can buy Lozol or other antihypertensive medication from our med store without Rx but it would be wiser to consult your healthcare provider to get a personalized assessment of your condition and treatment instructions appropriate namely for you.
The principle of Lozol action
The formulation precludes the reuptake of sodium and increases its washing out with urine promoting water loss and subsequent arterial pressure lowing. Besides, it minimizes the responsiveness of the vessels’ walls to hormones responsible for the vessels narrowing and elevation of arterial tension. The optimal tension-lowering effect with slightly enhanced diuresis is obtained in the use of 2.5 mg.
The highest level in the body is obtained in two hours. It is washed out in fourteen hours mainly in urine.
Lozol contraindications for use
You should not buy generic Lozol if you have one of the following conditions:
- Intolerance of the substances contained in the tablets;
- Anuria or severe kidney failure (diuretic effects are reduced, azotemia may increase);
- Severe liver failure;
- Age under 18 years.
The use is possible only under a doctor’s approval in:
- Decompensated diabetes;
- Any impairment of the liver or kidneys;
- Low sodium and other disorders electrolyte balance;
- Ischemic heart disease;
- Extended QT interval;
- Use of formulations that elongate QT interval.
The medication is supplied in two different dosages of the active substance per pill – 1.25 mg and 2.5 mg. Either of the dosages are taken once daily. The highest dosage per day is 2.5 mg. The higher dosages must not be used as they do not provide a more powerful diminishing in the blood tension but enhance diuresis.
If the effect from the diuretic use is insufficient, your healthcare provider can prescribe you additional antihypertensive medications which you can also buy at our online pharmacy at an attractive price. But please do so and start taking them only after consulting a specialist. Otherwise, you may end up using inadequately high dosages and suffer from an acute drop of arterial pressure below the target level.
The signs of an overdose of Lozol include low sodium and potassium, nausea, drop of arterial tension, drowsiness, lightheadedness, confusion, polyuria or oliguria, and anuria.
The emergency measures include induction of vomiting, gastric lavage and use of sorbents. Then, the normalization of electrolyte balance should be made at a hospital.
Lozol adverse effects
The most adverse reactions from the medication are dose-dependent, i.e. the higher the dosage you use, the higher is the risk of negative effects development.
- Blood disorders (for instance, low hemoglobin);
- Lightheadedness, drop of arterial pressure, fainting, etc.
- Arrhythmia, ventricular tachycardia;
- Nausea, constipation, dry mouth, pancreas dysfunction, liver dysfunction, hepatitis;
-Allergic reactions, mainly on the part of the skin in individuals who are predisposed to allergic such as rash, purpura, angioedema, urticaria, a flare-up of lupus erythematosus, and photosensitivity reactions.
- Diagnostics disorders include QT interval extension, elevated uric acid, and plasma glucose levels.
This probable adverse effects caused by the medication use do not mean that they will necessarily develop when you buy Indapamide and start using it. But you are more likely to suffer from some of these adverse reactions if you have predisposing factors, for instance, gastrointestinal tract diseases, history of allergic reactions, heart diseases, and so on. Thus, if you have any disorders or diseases even the ones not listed in the contraindications for the formulation use, you must inform your doctor about them and get a consultation.
It is not advised to combine Lithium with the formulation as it can contribute to the elevation of Lithium’s toxic effect.
The danger of arrhythmias and extension of QT interval is high in the simultaneous use of the formulation with astemizole, erythromycin, and antiarrhythmic medications.
The effect of Lozol is lowered by the use of NSAIDs, glucocorticoids, and adrenergic receptors agonists.
Baclofen enhances the effect of Lozol.
The danger of low potassium is high in the utilization of the medication with diuretics, cardiac glycosides, glucocorticoids and mineralocorticoids, Adrenocorticotropic hormone, laxatives, and amphotericin B.
ACE inhibitors when used simultaneously with the formulation lift up the danger of postural tension drop and kidney failure especially in individuals with kidney artery stenosis.
Indapamide lifts the danger of kidney dysfunction when using iodine agents in high doses when dehydrated. Tricyclic antidepressants and antipsychotics can enhance the blood-tension-lowering effect and elevate the risk of postural hypotension.
The formulation lowers the action of indirect anticoagulants so their dosages should be raised.
The pills strengthen the blockade of neuromuscular transmission that develops under the influence of non-depolarizing muscle relaxants use.
This list contains only the most notable interactions. If you take any other medications when you plan to buy generic Indapamide, read the package insert for full information or better consult a doctor.
When undergoing the course with the formulation, the monitoring of potassium, sodium, magnesium in the blood plasma, pH, and level of glucose, urea, and nitrogen must be done. The most closely monitored must be the individuals with cirrhosis especially with swelling and accumulation of free fluid in the abdominal cavity; ischemic heart disease, chronic heart disease, diabetes, seniors, and individuals with extended QT interval.
Acute dehydration during the therapy can cause acute kidney failure.
Indapamide may give a positive result in doping control.
Where can you buy Lozol?
We offer you to order generic Lozol so that you could undergo the therapy you need at a fraction of the price of the branded medication.
4RXStore will ship your order anywhere where international mail is available including to the UK, U.S., and so on. We ship within 7-25 days based on the shipping type chosen.
Our doctor prescribes online for free, and there is no doctor’s consultation fee.
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.
For more answers see the FAQ section