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Generic Cholesterol drugs


What is cholesterol?

Cholesterol is a natural fat (lipophilic) alcohol contained in the cell membranes of all living organisms. High level of cholesterol in the blood is called hypercholesterolemia. High blood cholesterol or hypercholesterolemia is one of the most important risk factors for myocardial infarction. The liver produces cholesterol in the required amount and therefore people should not consume cholesterol additionally.

Cholesterol is soluble in fats and organic solvents but insoluble in water. About 80% of cholesterol is produced by the human’s body (liver, intestines, kidneys, adrenals, gonads), the remaining 20% comes from food.

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Fatty substances are called lipids. Cholesterol bound with proteins is called lipoprotein.

There are two types of lipoprotein:
  – Lipoprotein of high density;
  – Lipoprotein of low density.

Each of them is used in assessing the risk for development of cardiovascular diseases.  Cholesterol and triglycerides are two main kinds of lipids, transported by blood. Cholesterol binds with proteins to transport with blood throughout the body.

Triglycerides are another name of fat. Triglycerides are delivered to cells by the same lipoproteins that transport cholesterol. Fats are important source of energy. Some of the triglycerides are ingested with fats contained in food.

What is "bad" and "good" cholesterol?

The highest level of cholesterol in the blood is contained in low density lipoproteins (LDL), which deliver it to the tissues of the body, including the heart through the coronary artery. Cholesterol in LDL plays the most important role in the formation of plaques (accumulations of fatty substances) on the inner walls of the arteries, which in turn leads to hardening of the arteries (including coronary arteries) and to myocardial infarction. That is why cholesterol contained in the LDL is called "bad" cholesterol. High level of LDL increases the risk of heart disease.

HDL cholesterol transports the same cholesterol but it is not involved in the formation of plaques. In essence, the function of proteins in HDL consists in removing excess cholesterol from tissues. This explains that HDL cholesterol is called "good" cholesterol.

There is a direct correlation between high levels of triglycerides and the risk of heart disease development, especially if your HDL is lowered. Additional amounts of triglycerides are produced during the admission of carbohydrates, proteins, alcohol and, accordingly, calories in amount greater than needed.

What can we do to keep cholesterol at normal level?

Main recommendations:
  – Keep optimal weight.
If your weight is considerably higher than normal, try to lose a few pounds. People suffering from overweight often observe increased cholesterol.
  – Avoid food containing trans fats.
They are contained in partially hydrogenated oils and are considered to be even more dangerous for the heart than saturated fats. Therefore, you should carefully read the labels on product packaging.
  – Eat less fatty food.
There is no need to eliminate fats from food completely. You can substitute saturated fats and oils to polyunsaturated oils such as corn, sunflower, safflower, soy or olive oil. Avoid products rich in saturated fats because they increase LDL cholesterol more than any other component of any product. Highly saturated fats include all animal, hydrogenated, as well as some vegetable fats as coconut and palm oil.
  – Try to eat less products containing cholesterol.
It is known that some products contain cholesterol, and their consumption contributes to hypercholesterolemia. Products rich in cholesterol: animal organs (liver), shellfish, whole milk, eggs. Try to find time for walking or other activities.
  – Do not smoke.
Smoking increases the level of cholesterol in the blood and harms the heart and blood vessels.
  – Be physically active.

Physical activities play an important role in the maintenance of normal heart function. Exercises, such as swimming, cycling, running and other activities, including climbing stairs, housework, working in the garden have a particularly beneficial effect.

Studies have shown that consumption of fiber is very important for cholesterol lowering. The good sources of fiber include oats, barley, dried beans, peas, apples, pears and carrots.

Medications against hypercholesterolemiaur online pharmacy offers you such generic preparations: Atorvastatin, Crestor, Lopid, Mevacor, Pravachol, Tricor, Zetia, Zocor.

Atorvastatin is indicated during primary hypercholesterolemia, combined hyperlipidemia, disbetalipoproteinemiya, family endogenous hypertriglyceridemia, homozygous familial hypercholesterolemia.

Crestor is indicated during hypercholesterolaemia or mixed hypercholesterolemia, family homozygous hypercholesterolemia.

Mevacor is indicated during primary hypercholesterolemia with high concentrations of LDL, combined hypercholesterolemia and hypertriglyceridemia, hyperlipoproteinemia, atherosclerosis.

Lopid is indicated during hyperlipoproteinemia, secondary hyperlipoproteinemia caused by diseases which are difficult to treat (diabetes, gout, hypothyroidism).

Pravachol is indicated during primary hypercholesterolemia, high cholesterol in combination with hypertriglyceridemia, prevention of coronary heart disease.

Zocor is indicated during primary hypercholesterolemia, combined hypercholesterolemia and hypertriglyceridemia, hyperlipoproteinemia, prevention of myocardial infarction (to slow the progression of coronary atherosclerosis) and insult.

Tricor is indicated during hypercholesterolemia (type IIa), endogenous hypertriglyceridemia (type IV) and their combination.

Zetia is indicated during primary hypercholesterolemia, in combination therapy with statins, as an adjunct to diet (with statin monotherapy), homozygous familial hypercholesterolemia.

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