Generic Medication guide:
What is Lipitor?
Lipitor is one of the names registered to market a medicinal substance with an unpatented name Atorvastatin. The medication is sold under a variety of names while having the same composition and effect.
Atorvastatin is a third-generation hypolipidemic drug from the group of statins. It substantially drops cholesterol but is encouraged to be utilized only after other base methods of normalization such as low-fat diet, physical exercising, and loss of excess weight did not improve the level of cholesterol sufficiently.
The medication diminishes cholesterol levels by a certain enzyme participating in the transformation of consumed fats to lipids (cholesterol) in the body. Lipitor also increases the number of “hepatic” low-density lipoprotein (LDL) receptors in the body, which leads to the enhanced capture and dissimilation of LDL. It also diminishes the formation of LDL, which is considered “bad” cholesterol.
Lipitor drops the level of overall cholesterol by 31-47%, LDL - by 40-62%, apolipoprotein B - by 35-52% and triglycerides - by 13-35%; besides it contributes to the rise in “good” cholesterol called high-density lipoprotein and apolipoprotein A.
Indications for Lipitor use
Your doctor can tell you to buy Lipitor for:
- Hyperlipidemia,
- Combined hyperlipidemia,
- Dysbetalipoproteinemia,
- Familial endogenous hypertriglyceridemia and type IV.
- Homozygous hereditary hypercholesterolemia.
- Cardiovascular diseases with increased risk factors for its occurrence such as age over 50 years old, smoker, elevated blood tension, genetic predisposition), including secondary to dyslipidemia prevention to reduce the overall risk of death, heart diseases, and so on.
When is the use of Lipitor prohibited?
Even you have the indications for the formulation use, you must not buy Lipitor and use it in:
- Allergy or intolerance of the medication’s components;
- Active liver disease;
- Pregnancy and lactation.
The use is possible but should be limited in:
- History of liver diseases,
- Severe electrolyte imbalance,
- Endocrine and metabolic disorders,
- Alcoholism,
- Lowered blood tension;
- Severe acute infections (sepsis),
- Uncontrolled seizures,
- Extensive surgery,
- Trauma,
- Age up to 18 years.
Adverse effects of Lipitor
The most frequent adverse effects related to the pills use that occur in 1% or more are trouble falling asleep, headache; nausea, diarrhea, abdominal pain, bloating, constipation, and muscle pain.
In less than 1% of users the following adverse effects are developed:
- General malaise, lightheadedness, low blood tension.
- Vomiting, loss of appetite, liver or pancreas dysfunction.
- Back pain, cramps.
- Skin rash, anaphylaxis, swelling;
- Other: erectile dysfunction, weight gain, chest pain, kidney failure, hair loss, fatigue, and others.
- Atorvastatin renders a load on a heart muscle.
How is Lipitor used?
Before you buy Atorvastatin, you should know that you need to start a low-fat diet before the course and maintain it during the use of the formulation.
The pills are taken at any time of the day.
The initial dosage is 10 mg once a day. It can be raised once in a month. The highest daily dosage is 80 mg in one intake.
In hypercholesterolemia and hyperlipidemia, 10 mg is appointed once a day. In hypercholesterolemia, 80 mg is appointed once a day.
Overdose signs and treatment
An overdose with the formulation is manifested in the intensifications of the listed-above adverse effects. It requires symptomatic and supportive therapy. Interactions of Lipitor with other formulations
If you take any medications or plan to start using them while using Atorvastatin, make sure to inform your doctor.
- In the same time use of the formulation with cyclosporine, fibrates, protease inhibitors, erythromycin, clarithromycin, azoles medicines plasma Atorvastatin level elevates.
- Antacids (medicines that lower stomach acidity) lower the level of the formulation in the medication by 35%.
- When the formulation is used along with Digoxin, the levels of the later in the body raise by around 20%.
- The medication elevates by 21% the level of oral birth control in the blood.
- The lipid-lowering effect of use with colestipol is much higher to that for each formulation separately.
Precautions
- The use of Lipitor can induce liver dysfunction which is why it is important to check the liver function before the course and throughout it (in six weeks, after every dosage increase, and every half of a year). Liver function changes usually occur within the first three months of therapy. If the level of liver enzymes is elevated, the individual should be supervised until the indicators are back to normal. If the levels of the enzyme are three times higher than the upper norm, the dose must be lowered or the therapy discontinued at all.
- Lipitor affects muscles. In some cases, it caused muscle pain without any complications. Individuals with diffuse myalgia, weak muscles or substantial increase of creatine phosphokinase are in a high-risk group. In the development of muscle pain, it is important to define the activity of creatine phosphokinase and if its elevated level is persistent, the dose of Lipitor must be reduced or the therapy discontinued.
- The use of the medication must be ceased right away in the occurrence of risk factors of acute kidney failure. The risk factors include acute severe infection, lowered blood tension, surgery, injury, severe metabolic and endocrine disorders, as well as electrolyte imbalance.
- You should right away consult your physician in the occurrence of sudden pains or muscle weakness especially if they are accompanied by general malaise and fever.
Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.
Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.
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