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4RX Store > Medication List > Gastrointestinal drugs > Order Damizol online

Gastrointestinal Medication (Damizol)

Generic name:
Brand name:
Diloxanide Furoate / Metronidazole
The medication known as Damizol is based on two active agents - Diloxanide Furoate and Metronidazole. This combination ensures a potent effect in the treatment of amoeba infections due to the multifaceted action aimed from the different directions. The medication can be used even in children aged older than 5 years. Read our guide to know about the recommended dosages, side effects, precautions, interactions, and other useful patient information.
Indications: Intestinal amoeba infections
The medication renders a combined effect on intestinal amoeba infections and ensuring the curing in just five days of therapy
Cipla - Caring for life
Cipla - Caring for life

Abbott - A promise for life
Abbott - A promise for life
Diloxanide, Furoate, Metronidazole
Damizol (Generic Diloxanide Furoate / Metronidazole)
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Order Generic Diloxanide Furoate / Metronidazole Buy Damizol 250/200mg

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  Generic Medication guide:

What is Damizol and when is it used?

Damizol is one of the commercial names used to market a combination formulation made of Diloxanide Furoate and Metronidazole. This combination is highly effective against bowel parasites. Since the medication’s formula is known and not covered by the copyright, it can be produced and sold by other companies under different names. For instance, at our online drugstore, you can buy Damizol cheap because it is sold under a less known name.

Short drug info
Trade names Damizol, other
Drug class Antiphrastic
Pregnancy category In general: contraindicated
Routes of administration By mouth
Legal status In general: prescription-only
Bioavailability 100%
Half-life 8-10 hours
Metabolism Liver
Elimination half-life 20–40 minutes
Excretion Urine (35-65 %), feces

The potent action of the formulation is due to the combined effects of two separate substances. Diloxanide Furoate renders the effect in the gastrointestinal tract and eliminates amoeba infections. The substance is used to treat an asymptomatic infection, i.e. when an individual is a carrier but hadn’t developed the symptoms yet.

Metronidazole in its turn is an antibacterial medication that is used to treat amebiasis, urogenital trichomoniasis, non-specific vaginitis, giardiasis, surgical infections caused by metronidazole-sensitive anaerobic microorganisms, and as a substitute for the intravenous treatment of infections caused by anaerobic microorganisms sensitive to Metronidazole.

Indications for Damizol use

You can buy generic Damizol to treat:

- Amebiasis of the bowel,

- Urogenital trichomoniasis,

- Non-specific vaginitis,

- Giardiasis.

Please note that only a specialist can choose the best medication for your problem and prescribe the correct treatment course and its duration.

When is the use of the medication prohibited?

The use of the formulation is contraindicated in an elevated sensitivity or intolerance of the pills’ components.

How is Damizol used?

The pills should be taken with meals to avoid an upset stomach.

- Adults: should use 2 pills three times a day for five days. The course may be extended to ten days for the relapsing condition.

- Kids (five to twelve years): should be given half of a pill or one pill three times a day for 5 days.

What adverse effects can the medication cause?

Before you buy Diloxanide Furoate/Metronidazole, you should know that you can develop certain negative effects while using the medication such as:

- Pain in the abdomen,

- Mild nausea,

- Burning sensation in the mouth,

- Headache and dizziness.

- Allergy.

If you have any signs of allergic reactions such as skin rash or swelling, you should immediately discontinue the course and inform your healthcare provider.

Interactions and precautions for Damizol use

Mechanism of action Unknown. Diloxanide may inhibit protein synthesis.
Absorption Bioavailability is 90% (in diloxanide parental form), however diloxanide furoate is slowly absorbed from the gastrointestinal tract.
Volume of distribution Not Available
Protein binding Not Available
Metabolism Hydrolyzed to furoic acid and diloxanide, which undergoes extensive glucuronidation (99% of diloxanide occurs as glucuronide and 1% as free diloxanide in the systemic circulation).
Route of elimination Renal (90%, rapidly excreted as glucuronide metabolite). 10% is excreted in the feces as diloxanide.

- Rifampicin. Decreased plasma levels of the anti-amoeba medication are observed due to elevated hepatic metabolism due to rifampicin. Clinical observation is indicated; a dose higher dosages of Damizol may also be required along and after rifampicin treatment.

- Lithium. An elevation in blood lithium levels with the intensification of toxic levels, with signs of an overdose of lithium. It is necessary to carefully control the level of lithium in the blood, dose adjustment may be required.

- Fluorouracil (and, by extrapolation, tegafur, and capecitabine). An elevation in the toxicity of fluorouracil due to a slowdown in its elimination from the body is possible.

- Metronidazole elevates the blood levels of anticoagulants which can result in bleeding.

- The simultaneous use of medicines that enhance the effect of liver enzymes, such as phenytoin or others may speed up the washing of Damizol resulting in its lowered levels and effect.

- The combination with medicines that diminish the liver enzyme's effect, such as cimetidine, may extend the half-life and diminish washing out of Damizol resulting in the enhancement of adverse effects,

- The use of alcohol is prohibited with the medication because it can result in such adverse effects as belly cramps, nausea, vomiting, and others.

- The formulation use must be avoided during pregnancy, especially during the first three months.

- Metronidazole is found in breast milk so it must not be used by breastfeeding women.

- In senior patients, the washing out of Damizol may be slowed down, so the control over the serum levels is required.

- For individuals with severe liver failure, a dosage lowering should be made by a doctor.

- In the case of manifestations characteristic of encephalopathy or cerebellar syndrome, the patient's therapy must be reviewed, and the use of Damizol should be discontinued.

- After receiving the first dose of the medications, patients may experience psychotic reactions that threaten the safety of patients, especially if they have a history of mental disorders. If this happens, you need to cancel metronidazole, inform your doctor about it and immediately begin appropriate therapeutic measures.

- Hematologic effects. In patients with a history of hematological abnormalities or who receive the drug in high doses and/or for a long time, it is necessary to regularly perform a blood test, especially regarding the content of white blood cells.

- In individuals with leukopenia, the decision on whether to continue treatment with the medication depends on the severity of the infection.

- The formulation may reduce the effectiveness of the oral birth control so women of fertile age who use it must use condoms while undergoing the course with Damizol.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

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