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4RX Store > Medication List > Gastrointestinal drugs > Order Prevacid online

Gastrointestinal Medication (Prevacid)

Generic name:
Brand name:
Prevacid is a medication based on Lansoprazole. It suppresses the production of gastric acid and lowers its acidity. These effects are beneficial for stomach and duodenum ulcers, GERD, and conditions in which excessive gastric juice production is observed such as Zollinger-Ellison syndrome. The conditions require different dosages and sometimes even combination of several medicines (for instance, in bacterial-caused ulcers). Read the guide below to know all needed information about the drug use.
Stomach and duodenum ulcer, Non-cancerous gastric ulcer, Erosive-ulcerative esophagitis, Gastroesophageal Reflux Disease (GERD), Zollinger-Ellison syndrome, Helicobacter pylori (combination therapy)
The medication helps to treat stomach and duodenum ulcer and other conditions that require lowered stomach juice acidity effectively
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Prevacid (Generic Lansoprazole)
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  Generic Medication guide:

What is Prevacid and when is it used?

Prevacid is a brand name of the Japanese pharmaceutical company Takeda. The medication sold under this name is based on the substance Lansoprazole which can be also found under different names. If you wish to buy Prevacid at a lower than the usual price, you should look for a generic version from our drugstore.

Short drug info
Trade names Prevacid, others
Pregnancy category
AU: B3

US: B (No risk in non-human studies)
Routes of administration by mouth
Legal status
UK: POM (Prescription only)

Drug class proton pump inhibitor
Bioavailability 80% or more
Protein binding 97%
Metabolism Liver (CYP3A4- and CYP2C19-mediated)
Elimination half-life 1–1.5 hours
Excretion Kidney and fecal

Pharmacological action - antiulcer.

The formulation blocks the final stage of stomach acid production. In the body, it transforms into the active form - sulfonamide, which irreversibly interacts with proton pump, an enzyme that promotes the production of stomach acid. Prevacid reduces fasting and after-meal acidity elevation of gastric juice and its volume. The rate and potency of suppression of acid production are dosage-dependent.

The medication also has a gastroprotective effect due to the enhanced oxygenation of the mucous membrane and enhanced secretion of bicarbonates. Besides it suppresses the growth of Helicobacter (bacteria that causes ulcers), and increases the anti-Helicobacter activity of other medicines. Prevacid provides faster healing and amelioration of symptoms of duodenal ulcer (85% heal after 4 weeks of 30 mg/day intake). It is also effective in the therapy of the stomach and duodenum ulcers resistant to H2 blockers. The recurrence rate of peptic ulcers after treatment is 55–62%. With reflux esophagitis, a complete cure by the end of eight weeks of use (30 mg/day) is observed in 88.7%.

When can you use the medication?

You can buy generic Prevacid for:

- Non-ulcer dyspepsia;

- Stomach and duodenum ulcer;

- Non-cancerous gastric ulcer;

- Erosive-ulcerative esophagitis;

- Gastroesophageal Reflux Disease (GERD);

- Zollinger-Ellison syndrome;

- Helicobacter pylori infection (combined treatment).

Contraindications for Prevacid use

- Hypersensitivity;

- Cancerous neoplasms of the digestive tract;

- Pregnancy (especially the first trimester), breast-feeding.

Application restrictions

Impaired liver function, age up to 18 years, old age.

Dosage and administration

It should be used by adults inside. Usually, the dose is 30 mg once a day 30-40 minutes before a meal. Capsules are taken without chewing, drinking 150-200 ml of water. If this is not possible, the capsule can be opened and its contents dissolved in a small amount of apple juice (approximately 1 tablespoon) and swallowed immediately without chewing.

The highest daily dose is 60 mg and in impaired liver function - 30 mg. For Zollinger-Ellison syndrome, the dosage can be increased.

If you need to take 2 daily doses, one is taken before breakfast, and the second before dinner.

If the dosage is not taken at an appointed time, it should be taken as soon as possible. However, if there is little time left before taking the next dose, the missed dose is skipped.

- Duodenal ulcer: 30 mg 1 time per day for 2-4 weeks. For ulcers caused by NSAIDs is 30 mg once a day. The course lasts 4-8 weeks.

- Benign gastric ulcer: 30 mg 1 time per day for 8 weeks.

- GERD: for moderate and severe forms of esophagitis, the dosage is 30 mg once a day for a month. If erosive esophagitis is not cured within 4 weeks, the length of the course can be twice as long.

- Helicobacter pylori: 30 mg twice a day (before breakfast and before dinner) with the prescribed antibiotics.

- Zollinger-Ellison Syndrome: The dose is selected individually so that the fasting acid secretion does not exceed 10 mmol/h. The advised starting dosage is 60 mg once a day before breakfast. If the patient takes doses greater than 120 mg, he should take the first half of the daily dose before breakfast, and the second half before dinner. Treatment continues until the clinical indication disappears.

Renal and liver failure

Impaired liver and kidney function of mild or moderate degree do not require dose adjustment.

- Severely impaired liver function requires the use of the lowest effective doses and not more than 30 mg per day.

Adverse reactions of Prevacid

- Allergic reactions;

- Angina pectoris, elevated blood pressure, and other heart-related symptoms;

- Constipation, vomiting, hepatotoxicity, jaundice, hepatitis, candidiasis of the mucous membranes of the esophagus, digestive tract, flatulence, polyps of the stomach, gastroenteritis, colitis, gastrointestinal bleeding, vomiting mixed with blood, increased appetite or decreased appetite, enhanced salivation, ground, rectal bleeding, stomatitis, violated taste perception, glossitis, ulcerative colitis.

- Diabetes mellitus, goiter, hyperglycemia/hypoglycemia.

- Blood composition disorders;

- Muscle and joints pain;

- Agitation, memory impairment, agitation, apathy, depression, dizziness/fainting, vertigo, hallucinations, fear, decreased libido, nervousness, insomnia, drowsiness, tremor, paresthesia, impaired thinking, confusion.

- Asthma, bronchitis, coughing, shortness of breath, nosebleeds, pulmonary hemorrhage, hiccups, pneumonia, inflammation/infection of the upper respiratory tract, pharyngitis, rhinitis.

- From the genitourinary system: menstruation, albuminuria, breast enlargement/gynecomastia, breast tenderness, interstitial nephritis, which can lead to renal failure, glucosuria, hematuria, impotence, kidney stones, and urinary retention.

For the whole list of adverse effects, please read the package insert that comes with the pills when you buy Lansoprazole.

Body System/ Adverse Reaction
Abdominal Pain

Interaction with other substances

Like other medications from the class, Lansoprazole lowers the level of Atazanavir (an HIV protease inhibitor). The simultaneous use of Atazanavir and Lansoprazole is contraindicated.

- Lansoprazole can raise the plasma levels of the medications metabolized by CYRZA4 (warfarin, antipyrine, Indomethacin, ibuprofen, Phenytoin, Propranolol, Prednisolone, diazepam, Clarithromycin or terfenadine) which can potentiate their adverse effects.

- Fluvoxamine leads to a significant raise (4 times) in the level of lansoprazole in blood plasma. In simultaneous use, dose lowering of Lansoprazole is needed.

- Inductors 2C19 and CYPZA4 - (Rifampicin, St. John's wort grass) can significantly lower plasma levels of the stomach medication. In simultaneous use, dose raise of Lansoprazole is necessary.

- Medicines upon absorption of which pH is important. Lansoprazole causes prolonged suppression of gastric secretion, therefore, the theoretically possible effect of lansoprazole on the active amount of drugs for which pH is important when absorbed (ketoconazole, itraconazole, iron salts, digoxin, and others).

- Sucralfate and antacid drugs can lower the bioavailability of Lansoprazole, through which Lansoprazole must be taken at least one hour after the use of these medicines. - When the medication is taken with Theophylline, to maintain clinically effective levels of Theophylline in individual patients, dosage adjustment of Theophylline is required at the beginning or upon termination of therapy with Lansoprazole.

- In the simultaneous use of Lansoprazole and tacrolimus, the level of tacrolimus in blood plasma may rise, especially in individuals who underwent transplantation.

Special recommendations

Before you buy generic Lansoprazole, the presence of cancerous tumors in the stomach and esophagus should be excluded, since the medication can suppress the symptoms and delay the correct diagnosis.

- Under the influence of Lansoprazole, the acidity of the gastric juice decreases, which leads to an increased risk of developing digestive tract infections induced by opportunistic microorganisms.

- Due to the limited information on the safety of using Lansoprazole as a maintenance therapy lasting more than 1 year, it is necessary to regularly evaluate the risk/benefit ratio for this group of patients.

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Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

For more answers see the FAQ section


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