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4RX Store > Medication List > Migraines drugs > Order Imitrex online

Migraines Medication (Imitrex)

 
Generic name:
Imitrex
Brand name:
Sumatriptan
Description:
The medication mostly known as Imitrex is based on the substance Sumatriptan. The medication is available under a variety of names when made and marketed by other companies. It is a potent medication that helps coping with acute migraine. The pills should be taken at the first signs of an acute migraine episode. Find out more about the drug, including the contraindications for its use, from the whole guide below.
Indications:
Acute migraines
Benefits:
The medication helps coping with acute migraine headaches effectively
Manufacture:
Sun Pharma
Sun Pharma
Synonyms:
Suminat, Imigran, Sumatran, Sumax
 
   
Imitrex (Generic Sumatriptan)
 
Actual product may differ in
appearance from image shown.
 
 
 
 

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  Generic Medication guide:

What is the medication sold under the name Imitrex?

Imitrex is a brand owned by GlaxoSmithKline pharmaceutical company. The active substance of this product is Sumatriptan, an anti-migraine medication. It is also produced by other companies and if you want to buy Imitrex at a low price, you can order a generic version of the medication made by the reputable generics manufacturer Sun Pharma on this webpage.

Sumatriptan is a selective agonist of serotonin 5HT 1 receptors located primarily in the blood vessels of the brain. Under the effect, the vessels narrow down which reduces the pain. The drug does not affect other subtypes of serotonin 5HT receptors.

The clinical effect is observed half an hour after taking the medication at a dose of 100 mg.

Short drug info
Trade names Imitrex, Imigran, others
Routes of administration By mouth
Pregnancy category C (Risk not ruled out)
Legal status
UK: General sales list (GSL, OTC)

In general: Rx (Prescription only)
 
Bioavailability 15% (by mouth) / 96% (sc)
Protein binding 14–21%
Metabolism MAO (monoamine oxidase)
Elimination half-life 2.5 hours
Washing out from the body 60% urine; 40% feces

Pharmacokinetics

Sumatriptan is quickly absorbed in the digestive tract, after 45 minutes its level in the blood serum reaches 70% of the maximum. Binding to blood plasma proteins is low - 14-21%. It is eliminated from the body mainly with urine.

Indications for Imitrex use

You can buy generic Imitrex to cope with acute migraines with or without an aura.

Dosage of Imitrex

The pills are taken as soon as possible after the start of a migraine attack. Do not chew tablets, swallow them with plenty of water.

For adults, the dosage is 1 tablet (100 mg), for some patients, the therapeutic dose may be 50 mg (half of a pill). If the pain does not disappear and do not decrease, do not increase the dosage. If the medicine is ineffective for you, consult your doctor about its replacement.

If the pain has diminished or disappeared and then resumed, it is possible to take the next dosage within the next 24 hours. Make sure that the interval between the intakes is at least 2 hours.

The highest dosage of the formulation within the 24-hour period should not exceed 300 mg.

Imitrex adverse effects

Adverse effect
Imitrex Number of patients=547 (%)
Placebo Number of patients=370 (%)
Atypical sensations
42
9
Tingling
14
3
Warm/hot sensation
11
4
Burning sensation
7
<1
Feeling of heaviness
7
1
Pressure sensation
7
2
Feeling of tightness
5
<1
Numbness
5
2
Tight feeling in head
2
<1
Flushing
7
2
Chest discomfort
5
1
Tightness in chest
3
<1
Pressure in chest
2
<1
Throat discomfort
3
<1
Discomfort: nasal cavity/sinuses
2
<1
Jaw discomfort
2
0
Weakness
<1
<1
Neck pain/stiffness
5
<1
Myalgia
2
<1
Dizziness/vertigo
12
4
Drowsiness/sedation
3
2
Headache
2
<1
Sweating
2
1

- On the part of the cardiovascular system: arterial hypotension, irregular heartbeat, slowed down or rapid heartbeat, increase in blood tension immediately after the pill intake; in some cases - heart rhythm disturbances, myocardial infarction, spasm of coronary arteries, the development of Reynaud’s syndrome.

- From the digestive system: nausea, vomiting, insignificant potentiating of the activity of liver enzymes, dysphagia, discomfort in the abdomen, colitis.

- From the nervous system: flushing, dizziness, weakness, rarely - drowsiness, feeling tired; in individuals with epilepsy or organic brain damage, in some cases convulsive seizures are possible.

- Ophthalmological manifestations in the form of diplopia, flickering before the eyes, lowered visual acuity are sometimes possible; very rarely - transient partial loss of vision (which is possibly related to the migraine attack itself).

- Allergic reactions: rash, itching, erythema, anaphylactic shock.

- Others: pain, tingling, burning sensation, pressure, or constriction.

These symptoms are temporary and can develop in any part of the body.

Contraindications for Imitrex use

Do not buy Sumatriptan in:

- Hemiplegic (migraine with weakness of one side of the body), basilar (migraine with predominant brainstem aura) symptoms and ophthalmic form of migraine (migraine with vision impairment);

- Coronary heart disease (myocardial infarction, post-infarction cardio sclerosis, angina) or the presence of symptoms characteristic for these conditions;

- Peripheral vascular occlusion diseases;

- Stroke or transient cerebral blood flow disorders;

-Severely impaired liver and / or kidney function;

- Therapy with medicines that contain ergotamine derivatives;

- Therapy with MAO inhibitors and during up to 14 days after their use discontinuation;

- Pregnancy;

- Patients under 18 and over 60 years of age;

- Allergy or intolerance of the drug.

Overdose

When ingesting more than 400 mg of the drug, no adverse reactions were observed, other than those listed in paragraph “Side effects”.

Treatment: in case of an overdose, it is necessary to observe the patient within 10:00, as necessary, conduct symptomatic therapy.

Interactions with other substances

When you buy Sumatriptan, keep in mind that it can negatively interact with other medicines:

- The simultaneous use with ergotamine causes a prolonged spasm of the vessels is noted. Sumatriptan can be taken no earlier than 24 hours after ergotamine-containing medicines. Ergotamine-containing drugs can be taken no earlier than 24 hours after taking Sumatriptan.

- The simultaneous use of the medication and MAO inhibitors is prohibited.

- Simultaneous use of Imitrex and selective serotonin reuptake inhibitors (SSRI) can cause weakness, hyperreflexia, and impaired movement coordination.

Application features

- The drug is not intended for use in the prevention of migraine.

- Sumatriptan should be prescribed with caution to individuals with epilepsy or any conditions associated with seizures, individuals with controlled elevated arterial tension since the drug can cause a transient increase in the arterial tension.

- When prescribing Sumatriptan to individuals with previously undiagnosed migraine or with migraine, which is accompanied by atypical symptoms, it is necessary to exclude other neurological diseases or tumors. Individuals with migraine have a risk of cerebrovascular complications onset (including stroke or cerebral blood flow disorders).

- The drug should not be prescribed to individuals at risk of pathology from the cardiovascular system (postmenopausal women, men over the age of 40 years old, in risk factors for heart diseases), without preliminary examination. When side effects such as pain and a feeling of tightness in the chest appear, an appropriate diagnostic examination should be performed, as these symptoms may indicate coronary heart disease.

- The drug should be prescribed with caution in case of impaired kidney or liver function, in connection with a possible significant change in absorption, metabolism or withdrawal of Sumatriptan.

- In individuals with hypersensitivity to sulfonamides, the development of allergy (from skin manifestations to anaphylactic shock) is possible.

- Sumatriptan should be prescribed only if the migraine is confirmed.

- In the case of the simultaneous use of Sumatriptan and SSRI, it is necessary to carefully monitor the patient's condition.

- In a migraine, as well as during therapy with Sumatriptan, drowsiness is possible. Therefore, while taking Sumatriptan, patients cannot drive a car and engage in other potentially dangerous activities that require a high speed of mental reactions.

- With caution, the drug should be used during lactation. It is not recommended to breast-feed a baby within 24 hours after taking Sumatriptan.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

For more answers see the FAQ section

 

 
 
   
Product Reviews:
   

 
May / 23 / 2018 stephen brady   USA, Biscoe
  Quickly shipped - Many thanks!
   
 
 
Feb / 20 / 2018 Kevin Moran   USA, Texas
  Good package, fast delivery.
   
 
 
Feb / 15 / 2018 Phillip Moran   USA, Aurora
  Fast delivery, well packaged. All good!
   
 


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