What is the medication marketed as Jonac?

The product you may know as Jonac gel is a painkiller medication in a form of topically-applied gel based on Diclofenac, a non-steroidal anti-inflammatory substance used for different diseases. To buy Jonac gel cheap, choose a generic version available at our online pharmacy.

Pharmacological properties

Diclofenac belongs to the group of NSAIDs. It has a pronounced anti-inflammatory, as well as moderate antipyretic activity. The mechanism of action is due to inhibition of mediators of inflammation synthesis. By inhibiting the activity of the COX-1 enzyme, it reduces platelet aggregation. The formulation is effective in the therapy of rheumatoid conditions and inflammation due to injury. It diminishes pain, liquidates inflammation and edema with rheumatic or injury-induced inflammation, and betters the function of the muscular system. In the course of therapy of rheumatoid arthritis, the medication intensively penetrates the joint cavity, reduces pain at rest and during movement, helps to elevate the range of movements in the affected joints, and reduces morning rigidity and puffiness of the joints. A stable effect is observed within one to two weeks of treatment.

Pharmacokinetics

When applied to the skin, it is partially absorbed (3.3% of the locally used dose) and detected in blood plasma. The formulation penetrates well into tissues and joints fluid, where its level is higher than in the blood plasma. T1⁄2 from blood plasma is 1–2 hours, from synovial fluid - 3–6 hours.

Indications for Diclofenac gel use

You can buy generic Jonac gel for symptomatic treatment of pain, inflammation, and swelling in:

- Soft tissue damage: trauma to tendons, ligaments, muscles and joints (for example, due to dislocation); sports injuries;

- Localized forms of soft tissue rheumatism: tendonitis, localized forms of degenerative rheumatism (osteoarthritis of the peripheral joints and spine), and others.

Application

The drug is used externally in adults and kids over the age of 12 years. The dosage of the gel depends on the size of the affected area. Usually, 2–4 g of gel (a size of pea or walnut) is applied to the skin at the area in pain 3-4 times a day and is gently rubbed in. After you applied the formulation, wash your hands, except when it is the hands that are to be treated.

The length of course of use depends on the indications and effect of the therapy. After two weeks of continuous use, the therapy effectiveness and its continuation reasonability should be reviewed. The drug should not be used for more than 14 days in a row with soft tissue lesions or rheumatic diseases of soft tissue or for more than 21 days - in case of pain caused by arthritis unless the doctor has prescribed another.

If the medication is not used as appointed by a doctor, it is necessary to consult a physician if, after a week of use, the patient's condition has not bettered or even aggravated.

Elderly individuals, individuals with worsened liver and kidney function do not require dose adjustment.

Contraindications for Diclofenac gel use

Do not buy Diclofenac gel in:

- Allergy to Diclofenac and/or other components of the formulation.

- A history of asthma attacks, urticaria, or acute rhinitis due to aspirin or other NSAIDs.

Adverse reactions Diclofenac gel can potentially induce

- On the part of the skin: infrequently - itching, redness, exanthema, burning, swelling, rash (vesicular, papular, pustular), peeling and dry skin, dermatitis; rarely - bulbous dermatitis; very rarely - photosensitivity reactions, generalized skin rashes, eczema; -

From the immune system: very rarely - hypersensitivity reactions, angioedema, bronchospasm;

- From the respiratory system: very rarely - AD;

- From the digestive tract: adverse reactions are very rare after topical administration of drugs containing Diclofenac. When using large amount of gel or rubbing it into large areas of the skin, it is impossible to exclude the chance of systemic adverse effects, as well as allergic reactions in the form of angioedema, dyspnea.

Special Instructions

- Use during pregnancy and lactation. The use of the formulation is prohibited in the III trimester of pregnancy due to the possibility of developing weakness in the labor and/or premature closure of the ductus arteriosus, in the I and II trimester the use of the gel is possible only as prescribed by the healthcare provider in the case when the expected benefit to the mother outweighs the potential risk to the fetus. Animal studies have not revealed a single manifestation of the harmful effects of Diclofenac on pregnancy or fetal development, childbirth or postnatal development.

- Diclofenac sodium passes into breast milk in an insignificant amount; therefore, if there are substantial reasons for using the gel during breastfeeding, it should not be applied to the mammary glands or large areas of the skin and applied for a long time. The ability to influence the reaction rate Does not affect.

- The drug is not used in kids younger than 12 years.

Interactions of Diclofenac gel

You can safely buy generic Diclofenac gel and use it with other medicines because the systemic absorption of Diclofenac with topical use of the formulation is very low, the likelihood of interactions is minimal.

Overdose of Diclofenac gel

Overdosing can hardly occur because of the low absorption of the active agent into the systemic circulation when applied topically. If the drug is accidentally swallowed, immediately clear the stomach and take an a sorbent. Then the common NSAIDs-poisoning protocol is indicated.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

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