What is Theo-24 and when is it used?

The medication sold under the trademark Theo-24 has a water pill, spasms reducing, blood vessels dilating, and anti-asthma effects (it expands the bronchi).

You can find the same medication sold under another name if you look it up by the name of the active substance – Theophylline. At our online drugstore you can buy Theo-24 made by the large generic making company Sun Pharma.

The effect of the medication is due to binding to adenosine receptors. It also blocks phosphodiesterase, stabilizes cAMP and lowers the level of intracellular calcium. Theophylline relaxes the smooth muscles of internal organs (bronchi, digestive system and uterus), suppresses mast cell degranulation and reduces the level of allergy mediators (serotonin, histamine, etc.) in the blood (anti-allergic effect). Increases the tone of the respiratory muscles (intercostal muscles and diaphragm); dilates blood vessels of the lungs and improves blood oxygenation; inhibits platelet aggregation, enhances the resistance of red blood cells to deformation, suppresses thrombosis and normalizes microcirculation. The antianginal effect (increased oxygen delivery to the myocardium) is due to the expansion of the coronary arteries.

After oral administration, it is completely absorbed (bioavailability over 90%). Cmax in the blood is reached within 2 hours (normal form) and 6 hours (prolonged form). In blood, 40-60% bound to proteins. Penetrates through blood-tissue barriers. It undergoes biotransformation in the liver with the formation of inactive metabolites. The formulation is washed out mainly by the kidneys (up to 13% in adults and up to 50% in children - unchanged); partially it is washed out in breast milk.

Indications for Theo-24

use You can buy generic Theo-24 for the symptomatic treatment and prophylaxis of bronchospasm due to bronchial asthma, chronic bronchitis and emphysema.

How is Theo-24 used?

Theophylline tablets should be swallowed entirely. It should not be divided, broken or chewed.

The average initial dose in the first two days is 16 mg per kilogram of body weight or 400 mg (respectively, choose the smaller one), it should be used in two doses, and gradually increase to 800 mg per day in the following days to get the best results.

The optimal dose and duration of the course should be selected individually before you buy Theophylline pills, focusing on the nature of the course of the disease, the accompanying pathological processes, the nature of complex therapy, age, body weight, and metabolic features.

Adverse effects

Theophylline can cause The side effects of the formulation are usually mild. If the level of Theophylline in blood plasma surpasses 20 mcg/ml, nausea, vomiting, headache, anxiety, insomnia, and heartburn may occur.

When is Theo-24 contraindicated to be used?

You should not buy generic Theophylline for:

- Children,

- Pregnant women and during breastfeeding.

- Hypersensitivity to xanthine derivatives. It is also prohibited for patients with peptic ulcer of the stomach and duodenum in the exacerbation phase, epilepsy (with the exception of those using appropriate anticonvulsants), with acute myocardial infarction, severe arterial hypertension, tachyarrhythmia, hyperthyroidism, and severe liver dysfunction.

Overdose

When Theophylline concentrations in blood are higher than 20 g/ml, side effects such as vomiting, arrhythmia, diarrhea, increased irritability, tremor, insomnia, and very severe convulsions occur, coma can develop which can lead to death.

Manifestations of Theophylline toxicity in overdose

Interaction with other medicines

- Toxic synergism with ephedrine was noted; this can also happen with other bronchodilators sympathomimetics.

- Allopurinol, Phenobarbital, cimetidine, norfloxacin, ciprofloxacin, erythromycin, oral contraceptives, and Propranolol contribute to an increase in Theophylline concentration in blood plasma.

- Phenytoin, Methotrexate, and Rifampicin reduce Theophylline concentration.

- If you use any medicines at the time you want to order generic Theophylline, consult your doctor first.

Special recommendations

Despite the fact that, subject to the dosage, the level of the medication in the blood plasma rarely exceeds 20 g/ml, the condition of patients who, for one reason or another, have weakened elimination of it, should be controlled even if they order Theo-24 without a prescription from an online drugstore.

They include:

- Persons with liver failure.

- Individuals older than 55 years, especially men with chronic lung diseases.

Pregnancy and lactation

While it is not known, Theophylline can have an adverse effect on the fetus, however, during pregnancy, xanthines should be used only in case of emergency.

Theophylline passes into breast milk and may induce negative effects in newborns. Serious side effects are unlikely and possible only when the concentration of the drug in the mother’s blood reaches a critical level.

- Elderly people whose Theophylline level in the blood exceeds 20 mcg/ml are more likely to experience side effects, such as irregular heartbeat or seizures than younger individuals.

- Less serious symptoms of Theophylline toxic effects (nausea, anxiety) can often occur in the initial stages of treatment, but are usually passing.

- Clinical data on the use of prolonged-acting Theophylline for the treatment of children are not available.

- Smoking significantly affects the metabolism and elimination of Theophylline. In individuals who smoke more than 20 cigarettes per day, the elimination half-life is reduced.

- Excretion of the active substance is increased in people with severe respiratory failure, with liver and kidney failure, viral infection, hyperthermia.

- Alcohol and caffeinated foods also affect Theophylline metabolism.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

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