Buy online cheap generic drugs from online Reputable Pharmacy, no prescription and free doctor consultation    
 
  Buy Quality RX from Reputable Online 4rx DrugStore  
Prescription for generic drug is reviewed by real doctor. Log In for 4RXStore CustomersHealth NewsBuy Online RX AffiliatesBuy Online RX F.A.Q.Buy Online RX Contact Us
 
  Search Sort by name:  A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z Support is Offline
 
 
Generic Drugs Category:  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
Herbals Category:  
 
 
 
 
   
Brand Drugs Category:  
 
 
 
 
   
 
 

4RX Store > Medication List > Women`s Health drugs > Order Estrace online

Women`s Health Medication (Estrace)

 
Generic name:
Estrace
Brand name:
Estradiol
Description:
Estrace is a trademark registered to market synthetic estradiol. This drug is used in the deficiency of natural estradiol due to various causes including removal of uterus. Other indications include lack of menstrual bleedings, irregular menstrual bleeding, underdeveloped genitals in women, infertility, and others. The medication must be used only if and as appointed by a doctor as it can cause severe adverse effects especially if used for a long time without control.
Indications:
Estrogen deficit in menopause including artificially induced, Lack of menstruation, Short and scarce period, Alopecia with hyperandrogenism, Increased body hair growth in polycystic ovary syndrome, Vaginitis, Underdeveloped genitals, Infertility, Prolonged pregnancy, Suppression of lactation, Hypertrichosis, Prevention of osteoporosis, Breast cancer with metastases, Prostate carcinoma, Urogenital disorders (dyspareunia, vulvovaginitis)
Benefits:
The medication replaces estradiol when it is needed for the treatment of genitourinary system
Manufacture:
German Remedies
German Remedies
Synonyms:
Evalon, Prognova, Progynova, Aerodiol, Agofollin, Alora, Altrad, Amnestrogen, Aquadiol, Bardiol, Climaderm, Climara, Combipatch, Compudose, Corpagen, Delestrogen, Dermestril, Dihydrofollicular Hormone, Dihydrofolliculin, Dihydromenformon, Dihydrotheelin, Dihydroxyesterin, Dihydroxyoestrin, Dimenformon, Diogyn, Diogynets, Divigel, Encore, Esclim, Esterified, Estinyl, Estraderm, Estradurin, Estraldine, Estrasorb, Estreva, Estrifam, Estring, Estroclim, Estrofem Forte, Estrogel, Estrol, Estrovite, Evex, Evorel, Extrasorb, Femestral, Femestrol, Feminone, Femogen, Fempatch, Femring, Femtrace, Femtran, Follicyclin, Ginedisc, Ginosedol, Gynergon, Gynestrel, Gynodiol, Gynoestryl, Gynpolar, Innofem, Lamdiol, Lynoral, Macrodiol, Macrol, Menest, Menorest, Menostar, Microdiol, Nordicol, Oestergon, Oestradiol, Oestrogel, Oestroglandol, Oestrogynal, Ovahormon, Ovasterol, Ovastevol, Ovociclina, Ovocylin, Perlatanol, Primofol, Profoliol, Progynon, Ricifon, Ritsifon, Sandrena Gel, Sisare Gel, Soldep, Sotipox, Syndiol, Systen, Tradelia, Trial Sat, Trocosone, Vagifem, Vivelle, Zerella, Zumenon
 
   
Estrace (Generic Estradiol)
 
Actual product may differ in
appearance from image shown.
 
 
 
 

Order Generic Estradiol Buy Estrace 1mg

 

Quantity (max. 2)   Package   Price, USD   You save

 

 

 

 

 

 

 

1
 
  84 pills
 
$44.00 ($48.95)
  $4.96

 

 

 

 

 

 

 

1
 
  112 pills
 
$54.39 ($61.35)
  $6.96

 

 

 

 

 

 

 

1
 
  140 pills
 
$66.05 ($78.25)
  $12.20

 

 

 

 

 

 

 

1
 
  168 pills
 
$78.65 ($94.00)
  $15.35

 

 

 

 

 

 

 

Price: $
Buy now
 

 

Order Generic Estradiol Buy Estrace 2mg

 

Quantity (max. 2)   Package   Price, USD   You save

 

 

 

 

 

 

 

1
 
  56 pills
 
$47.15 ($51.05)
  $3.91

 

 

 

 

 

 

 

1
 
  84 pills
 
$64.97 ($73.00)
  $8.02

 

 

 

 

 

 

 

1
 
  112 pills
 
$87.05 ($99.35)
  $12.31

 

 

 

 

 

 

 

1
 
  140 pills
 
$104.79 ($119.20)
  $14.41

 

 

 

 

 

 

 

Price: $
Buy now
 



 
  Generic Medication guide:

What is Esterase and when is its use appointed?

Estrace is one of the brands for artificial Estradiol which is a hormonal medication. It has the same physiological effect as natural hormone estradiol that is synthesized by the ovaries from the first menstruation and till menopause. If you need to buy Estrace according to your healthcare provider recommendations, you should know that it is manufactured by different companies and can be bought cheaper than the branded Estrace if sold under a less known name.

Short drug info
Trade names Estradiol, Estrace, Evalon, Prognova, Progynova, Aerodiol
Pregnancy use Contraindicated
Routes of administration Oral, sublingual, intranasal, topical/transdermal, vaginal, intramuscular or subcutaneous (as an ester), subdermal implant
Bioavailability Oral: <5%
Protein binding

~98%:

Albumin: 60%

SHBG: 38%

Free: 2%

Metabolism Liver (via hydroxylation, sulfation, glucuronidation)
Biological half-life

Oral: 13–20 hours

Sublingual: 8–18 hours

Topical (gel): 36.5 hours

Excretion

Urine: 54%

Feces: 6%

The medication causes changes (proliferative) in the endometrium, stimulates the development of genital organs, increases the excitability of the uterus, and inhibits lactation. In addition, estradiol regulates nitrogen metabolism, has a weak anabolic effect, and lowers blood lipids and cholesterol. It helps maintain a balance between osteoclasts and osteoblasts, reduces bone resorption, and promotes its formation.

The benefits of Estrace or its generic use are:

- Improved and timely endometrial rejection and regular period;

- Elevation of thyroxine, iron, copper, etc. in the blood;

- Increased synthesis in the liver of vitamin K-dependent coagulation factors;

- Anti-atherosclerotic effect;

- Lowering of bad cholesterol;

- Modeling of the receptors for to progesterone and normalization of smooth muscle tone;

- Transmission of intravascular fluid in the tissue and compensatory retention of sodium and water;

- Acceleration of leukocytes restoration in myelosuppression associated with radiation damage.

What are the indications for Estrace use?

You can buy generic Estrace for:

- Estrogen deficit in menopause including artificially induced;

- Lack of menstruation, short period, and other menstrual disorders;

- Alopecia with hyperandrogenism;

- Increased body hair growth in polycystic ovary syndrome;

- Vaginitis (in girls and seniors);

- Underdeveloped genitals;

- Infertility;

- Weak labor;

- Prolonged pregnancy;

- To inhibit lactation;

- Hypertrichosis;

- Prevention of osteoporosis;

- Breast cancer in men and women with metastases;

- Prostate carcinoma;

- Urogenital disorders (dyspareunia, vulvovaginitis);

- As a means of stimulating hematopoiesis in men with acute radiation damage.

When the use of Estrace is contraindicated?

- Hypersensitivity,

- Estrogen-dependent cancer or suspected,

- Liver tumors (including history),

- Sickle cell anemia,

- Herpes,

- Otosclerosis (including exacerbation during pregnancy),

- Retinopathy or angiopathy,

- Cholestatic jaundice or persistent itching (including during a previous pregnancy or while taking steroid medictions),

- History of gallbladder disease,

- Unusual genital or uterine bleeding of the unidentified cause,

- Thrombophlebitis or thromboembolic conditions in the active phase (except for breast or prostate cancer);

- Inflammatory diseases of the female genital organs (endometritis);

- Hypercalcemia associated with bone metastases of breast cancer.

If the medication is prescribed for cancer, doctor should assess the risks in case of diseases of the coronary or cerebral vessels, active thrombophlebitis or thromboembolic diseases as the medication can cause aggravation of these conditions.

Application restrictions

- Asthma,

- Diabetes,

- Migraine,

- Seizures,

- Elevated arterial tension,

- Heart failure,

- Coronary heart disease,

- Renal failure,

- Acute or chronic liver diseases (including a history) with a change in the performance of liver function tests,

- Hyperlipoproteinemia,

- Edematous syndrome,

- Endometriosis,

- Fibrocystic mastopathy,

- Porphyria,

- Pituitary tumors,

- Diffuse connective tissue diseases,

- Johnson or Rotor syndrome.

The medication use is prohibited during pregnancy, including presumed (estrogens may have an embryotoxic effect). Studies have shown the association of congenital malformations with the use of certain estrogens during pregnancy.

How to take estradiol?

Inside, without chewing, drinking a small amount of liquid, 2 mg/day, for 21 days, followed by a break of 7 days, after which treatment is continued. The duration of treatment is up to 28 weeks, after which an examination is carried out to decide on the continuation or cessation of the therapy.

In removed uterus or in menopause, treatment can be started any day. With the menstrual cycle preserved, the first pill is taken from the 5th day of the cycle (1 day of the cycle = 1 day of menstruation).

What adverse effects can Estrace cause?

When you buy Estradiol, you should know that its use can cause the following negative effects:

- Lightheadedness, headache, migraine, depression, visual impairment (change in the curvature of the cornea), discomfort when wearing contact lenses.

- From the cardiovascular system and blood (blood formation, hemostasis): elevated arterial tension, thromboembolism.

- From the digestive tract: nausea, vomiting (mainly of central origin when using high doses), pain in the epigastric region, flatulence, diarrhea, anorexia, cholestatic jaundice, cholelithiasis, hepatitis, pancreatitis, intestinal and biliary colic.

- From the genitals system: in women - “breakthrough” bleeding, uterine bleeding of unknown etiology, a change in the nature of uterine bleeding and spotting, metrorrhagia (a sign of an overdose of estradiol), premenstrual syndrome, amenorrhea, dysmenorrhea, an increase in the size of uterine fibroids or leiomyoma, changes in cervical secretion , changes in the nature of vaginal discharge, vaginal candidiasis, endometrial hyperplasia (if prescribed without a progestogen), uterus carcinoma (in menopause with an intact uterus), symptoms of cystitis; sclerosis of the ovaries; soreness, sensitivity and growth of mammary glands, increased libido; in men - soreness and sensitivity of the mammary glands, gynecomastia, decreased libido.

- From the skin: chloasma or melasma, contact dermatitis, hemorrhagic rash, acne, alopecia, hirsutism, pruritus.

- Other: changes in body weight, decreased tolerance to carbohydrates, aggravation of porphyria, spasms of the calf muscles; a violation of the exchange of sodium, calcium and water and as a result, peripheral edema.

 Relative and absolute risk seen in the estradiol use vs placebo

Event
Relative Risk CE/MPA vs placebo at 5.2 Years (95% CI*) (%)
Absolute Risk per 10,000 Women-years
Number of patients: Estrace – 8506 Placebo - 8102 Placebo vs Estradiol (%)
Coronary heart disease (Non-fatal)
1.29 (1.02-1.63)
30 (37)
Coronary heart disease death
1.32 (1.02-1.72)
6 (7)
Invasive breast cancer
1.26 (1.001.59)
30 (38)
Stroke
1.41 (1.07- 1.85)
21 (29)
Pulmonary embolism
2.13 (1.39-3.25)
8 (16)
Colorectal cancer
0.63 (0.430.92)
16 (10)
Endometrial cancer
0.83 (0.471.47)
6 (5)
Hip fracture
0.66 (0.450.98)
15 (10)
Death due to causes other than the events above
0.92 (0.741.14)
40 (37)
Deep vein thrombosis
2.07 (1.492.87)
13 (26)
Vertebral fractures
0.66 (0.440.98)
15 (9)
Other osteoporotic fractures
0.77 (0.690.86)
170 (131)

Interactions of Estrace

Before you buy generic Estradiol, consult your doctor if you take any other medicines. Estradiol reduces the activity of diuretics, anticoagulants, blood tension-lowering medications, and hypoglycemic agents. Reduces glucose tolerance (may require adjustment of the dosage regimen of antidiabetic medications). Estradiol enhances the effectiveness of lipid-lowering medicines.

- Inducers of microsomal liver enzymes, for example, some anticonvulsants and antimicrobials (including hydantoins, barbiturates, primidone, carbamazepine, rifampicin), can accelerate the metabolism of estradiol, increase the clearance of sex hormones and reduce clinical effectiveness.

- Folic acid and thyroid medications enhance the effects of estradiol. Significant alcohol consumption during treatment can lead to increased levels of circulating estradiol.

Overdose

Symptoms: nausea, vomiting. Treatment: maintenance of vital functions (against the background of medication withdrawal), symptomatic therapy.

Precautions for the substance Estradiol

- Before starting use, it is necessary to conduct a complete general medical and gynecological examination, including an examination of the abdominal and pelvic organs, mammary glands, blood pressure measurement, cytological analysis of the endometrium. It is necessary to exclude pregnancy. With prolonged therapy, such an examination should be carried out every 6-12 months.

- A month or a month and a half before the planned surgical intervention and/or extended bed rest, the treatment should be interrupted to avoid thrombosis.

- The course must be discontinued without any delay in the following cases: deep vein thrombosis, thromboembolic diseases, a significant rise in the arterial tension, the appearance of jaundice, the appearance of a migraine-like headache, and sudden visual impairment.

- In the use of the medication in hypertension, blood tension should be regularly monitored.

- In the initial period of treatment, individuals with diabetes need careful monitoring due to a possible drop in glucose tolerance.

- Changes in estrogen levels in the blood may affect the performance of certain endocrine and liver functions.

- Estrogens can cause fluid retention and swelling. Thus, individuals with impaired cardiac or renal function need close monitoring. - Inform your doctor about the simultaneous use of barbiturates, phenylbutazone, hydantoins, rifampicin, the appearance of irregular bleeding or unusually heavy bleeding in the breaks between the medication use and discomfort in the abdomen.

- In the event of irregular uterine bleeding, cytological analysis of the endometrium should be performed.

- During treatment, it should be borne in mind that the extended use of estrogen alone in the menopause can lead to endometrial hyperplasia and elevates the risk of uterine cancer. To lower the risks, an additional progestogen is necessary (usually within 10-12 days per month), which leads to the transition of the uterine mucosa to the secretory phase with its rejection and subsequent menstrual bleeding after cessation of progestogen administration. With the appearance of irregular menstrual flow (in women without a removed uterus), diagnostic curettage is necessary to exclude cancer of the uterus.

- Postmenopausal women who use the medication for a long time have raised risk of mammary gland cancer. A regular checkout of the mammary glands is necessary, including they should be taught regular self-examination. Particular caution should be exercised when prescribing the medication to women who have or have had nodular or fibrocystic changes in the mammary glands in the past. In such cases, careful monitoring and regular mammograms are necessary. - In women taking estrogenic drugs during menopause, there is a higher risk of gallstone disease.

- The drug is not a contraceptive and does not restore the ability to fertilize.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

For more answers see the FAQ section

 

 
 
   
Product Reviews:
   

 
Nov / 24 / 2016 Gabi Warasi   USA, Wolcott
  I ordered this medication 2 months ago. Estrace is a good generic. When compared to the brand Estradiol I did not notice the difference.
   
 


Write a Review:  

Tell us what you think about this drug and share your opinions with other people. Please make sure your review focuses only on this drug.
All reviews are moderated and will be reviewed within two business days. Inappropriate reviews will not be posted.
If you need additional information about the generic drugs, you can contact our RXShop.md customer service agents.
(A customer representative will get back to you asap).

 
Rating:
*
   
Your Full Name:
*
maximum 80 symbols
 
Your e-mail:
*
4RXStore.com does not buy, rent, or sell email addresses to or from third parties.
 
Country, City:
*
Separate by commas. Example: USA, California
 
Your Review:
*
maximum 1000 symbols
 
Enter text shown below:
*
     
     
    I accept the Terms & Conditions and the Privacy Policy.
     
   
 
 
  Copyright 2009 2020 4RXStore.com All rights reserved. All trademarks and registered trademarks are the property of their respective companies.
 
 
  We accept:
   
  e-check Bitcoins 
 
Contact US | Privacy policy | Refund/Reship policy | Terms of services | Health News | Articles | Most Popular | Drug manufacturers
 
 
Modalert | Cialis | Valtrex | Propecia | Proventil | Yasmin | Zitromax | Finpecia