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4RX Store > Medication List > Women`s Health drugs > Order Parlodel online

Women`s Health Medication (Parlodel)

 
Generic name:
Parlodel
Brand name:
Bromocriptine
Description:
The medication is used for multiple conditions in which the regulation of prolactin level is needed such as benign breast tumors and cysts, menstrual irregularities, suppression of lactation, and others. Find out how to use the drug, what side effects it can cause, and other useful information from the complete guide.
Indications:
Amenorrhea, Oligomenorrhea, Insufficiency of the luteal phase, Secondary hyperprolactinemia caused by other drugs, Prolactin-independent female sterility, Polycystic ovary syndrome, Anovulatory cycles, Infertility associated with hyperprolactinemia, Premenstrual syndrome, Lactation suppression, Benign neoplasm in the mammary gland, Fibrocystic breast disease
Benefits:
The medication helps to normalize prolactin levels when needed
Manufacture:
Serum Pharmaceuticals
Serum Pharmaceuticals
Synonyms:
Proctinal
 
   
Parlodel (Generic Bromocriptine)
 
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Order Generic Bromocriptine Buy Parlodel 2.5mg

 

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  Generic Medication guide:

What is Parlodel and when is it appointed?

The medication sold under the name Parlodel among others is based on the active agent Bromocriptine. It is an inhibitor of prolactin secretion and a dopamine receptor stimulator. The medication is used for the endocrine and nervous system disorders.

If you need to buy Parlodel, you can get the medication at our online drugstore. We offer high-quality generic drugs identical to the branded ones at the lower prices.

Short drug info
Trade names Originally Parlodel, others
Other names 2-Bromoergocriptines
Pregnancy category

AU: A

US: B (No risk in non-human studies)

Routes of administration oral, vaginal, intravenous
Legal status

AU: S4 (Prescription only)

CA: Rx-only

UK: POM (Prescription only)

US: Rx-only

Bioavailability 28% of oral dose absorbed
Metabolism Extensively liver-mediated
Elimination half-life 12-14 hours
Excretion 85% bile (faeces), 2.5-5.5% urine

Indications for Parlodel use

In gynecology, the medication is used for:

- Menstrual irregularities and female sterility.

Diseases that depend on prolactin levels and conditions with or without hyperprolactinemia:

- Amenorrhea;

- Oligomenorrhea;

- Insufficiency of the luteal phase;

- Secondary hyperprolactinemia caused by other drugs (for example, some psychotropic or antihypertensive drugs).

- Prolactin-independent female sterility:

- Polycystic ovary syndrome;

- Anovulatory cycles (which have arisen under the influence of antiestrogens, for example, clomiphene);

- Infertility associated with hyperprolactinemia.

- Premenstrual syndrome:

- Chest pain; breast swelling associated with the phase of the cycle; flatulence; mood changes.

- Hyperprolactinemia in men (with or without galactorrhea):

- Prolactin-dependent hypogenitalism (oligospermia, loss of libido, impotence).

- Lactation suppression:

- Due to medical indications including early stages of postpartum mastitis;

- Prevention of lactation after an abortion.

- Benign neoplasm in the mammary gland:

- Mastalgia (including those associated with premenstrual syndrome or benign focal or cystic changes);

- Benign focal and/or cystic conditions, in particular, fibrocystic breast disease.

How does Parlodel act?

Bromocriptine suppresses prolactin production without impacting levels of other hormones.

Bromocriptine prevents or inhibits lactation and restores prolactin-dependent menstrual cycles and ovulation. It is an effective treatment for amenorrhea and a lack of ovulation.

The medication eases the manifestations of polycystic ovary syndrome.

When is the use of the medication prohibited?

You should not buy generic Parlodel and use it in:

- Intolerance of the active substance, other ergot alkaloids, or to any other ingredients of the pills;

- In case of long-term treatment: signs of heart valve insufficiency obtained during echocardiography performed before treatment;

- Toxemia of pregnant women, postpartum and birth elevated blood tension, idiopathic or hereditary trembling, Huntington's chorea;

- Parlodel is prohibited to be used to suppress the production of milk in women with a history of atherosclerotic heart disease or other severe cardiovascular diseases or symptoms/history of severe mental disorders. Their doctor should carefully assess the expected benefits are potential risks;

- Bromocriptine cannot be taken simultaneously with other ergot alkaloids;

- The medication should not be prescribed in a history of fibrotic disorders or with signs of heart valve insufficiency obtained with echocardiography performed before treatment.

How is Parlodel used?

When you buy Bromocriptine, you should consult your doctor on how to use this medication. Here you can find general information which should be adjusted by a doctor who knows your condition and health history.

The pills should be always taken with food. The optimal dosage with the minimization of possible adverse effects is achieved through the gradual dosage increase.

- For the first day, the dosage is 1.25 mg taken before sleep. Then in two to three days, it is raised to 2.5 mg before sleep. It can be subsequently raised by 1.25 mg with an interval of two to three days till the daily dosage of 5 mg split into two intakes.

- To prevent the production of milk the dosage of 5 mg split into two intakes is taken for fourteen days.

- Suppression of milk production is made with the use of the first dosage of 2.5 mg with the raise to 5 mg split into two intakes in 2-3 days. The course is 14 days.

- Hyperprolactinemia is treated with the use of 7.5 mg split into several intakes. The maximum dosage is 30 mg a day. Infertile women without increased prolactin level should use 5 mg split into two intakes.

Individuals with kidney dysfunction may require dosage adjustments.

Overdose of Parlodel

The potential symptoms of an overdose include nausea, vomiting, dizziness, low blood tension, rapid heartbeat, sleepiness, hallucinations, confusion, and others. Treatment implies vomiting, intake of sorbents, and maintenance of normal blood pressure.

What adverse effects can Parlodel cause?

When you buy generic Bromocriptine, you should know that it can cause adverse reactions. The most common ones are nausea, vomiting headache, dizziness, and fatigue. These negative effects are usually mild and fade over the first days of the treatment.

The risk of adverse effects development can be minimized if the pills are taken with food. If the adverse effects are intense, the dosage can be lowered and maintained at a low level for several days and then raised to the previously used when the symptoms are gone.

Incidence of Parlodel adverse effects

Adverse reaction
Incidence (% of users)
Any adverse reaction 69%
Nausea 49%
Headache 19%
Dizziness 17%
Fatigue 7%
Lightheadedness 5%
Vomiting 5%
Abdominal cramps 4%
Nasal congestion 3%
Constipation 3%
Diarrhea 3%
Drowsiness 3%
Discontinuation of therapy due to adverse effects occurrence 5%

Side effects grouped by organ-system classes

- Metabolism and Nutrition Disorders: Anorexia.

- From the side of the psyche: confusion, insomnia, mental disorders; enhanced sex drive, pathological attraction to gambling.

- From the nervous system: headache, sleepiness, dizziness, dyskinesia, paresthesia; sudden falling asleep, and others.

- On the part of the organs of vision: visual impairment, the blurred field of vision.

- On the part of the organs of hearing and balance: tinnitus.

- From the side of the heart: irregular heartbeat, myocardial infarction, heart valve failure.

- From the vessels: orthostatic hypotension, hypertension, pallor.

- From the respiratory system: nasal congestion; shortness of breath.

- From the gastrointestinal tract: nausea, constipation, dryness of the mouth, vomiting, diarrhea, abdominal pain, bleeding from the gastrointestinal tract, ulcerative lesions of the gastrointestinal tract.

- On the part of the skin: skin allergic reaction, hair loss.

- From the side of the muscles: cramps of the calf muscles.

Interactions of Parlodel

Before you order Parlodel, make sure to inform your doctor if you use any other medications.

- The risk of negative effects caused by the drug increases if you consume alcohol.

- The medication must be cautiously used with blood tension-lowering medications.

- The level of the medication in the blood plasma can be increased if it is used along with erythromycin, other macrolide antibiotics, and octreotide.

- The effects of the medication can be lowered by the antagonists of dopamine (butyrophenones, phenothiazines), Metoclopramide and Domperidone.

- Sympathomimetics, e.g. phenylpropanolamine, isomeptene, increase the risk of toxicity.

- The medication use must not be combined with other ergot alkaloids.

- Caution is advised in the use of the medication with CYP3A4 inhibitors (e.g. azole fungicides, HIV medications).

Special recommendations for Parlodel use

- If you want to order generic Parlodel for benign breast tumors or premenstrual syndrome, keep in mind that it is not the first-line medication and not a preferable drug.

- The formulation is not advised to women with a history of raised blood tension or mental disorders.

- If the drug is used after labor, blood tension should be closely monitored at least for the first days since the medication can contribute to its increase. Particular care is needed for patients who use or have recently used) medicines that can change blood pressure.

- There are several cases of severe adverse events in recently giving birth women who used the medication to suppress lactation. These events are heart attack, stroke, or mental disorders. There is no proof that these negative effects are directly related to the medication use but in any risks, caution is needed.

- In case of hypertension, severe and persistent headache with visual impairment or any signs of toxicity to the central nervous system, treatment should be stopped immediately.

- Patients may develop hyperprolactinemia of idiopathic or medicinal origin, or due to diseases of the hypothalamus or pituitary gland.

- Women of reproductive age suffering from pathology unrelated to hyperprolactinemia should use the minimum effective dosages. This warning is necessary to avoid inhibition of prolactin to levels below normal, followed by impaired corpus luteum function. During treatment, such patients should use a reliable non-hormonal method of birth control, since it is known that oral contraceptives increase the level of prolactin in the blood serum.

- Women who need to use Parlodel for long periods need a gynecological examination (including cytological examination). Women who are in the period of menopause are recommended to undergo an examination once every 6 months, and women of reproductive age are recommended to be examined once a year.

- Individuals with a history of stomach ulcer should be carefully monitored throughout the formulation use.

- In patients using bromocriptine, especially for a long period and in high doses, pleural and pulmonary fibrosis, and constrictive pericarditis were occasionally observed.

- Several patients who have used Bromocriptine, especially over an extended period and at high doses, have experienced cases of retroperitoneal fibrosis. In the occurrence of symptoms, for example, back pain, puffiness of the lower extremities, impaired renal function), a patient should inform the doctor. -In case of diagnosis or suspicion of the presence of fibrotic changes in the retroperitoneal space, treatment the use of the formulation should be ceased.

- The medication use can cause drowsiness, dizziness, and other effects so it is advised to refrain from driving vehicles and operating machinery at least during the first days of the medication use. Besides, if these symptoms occur and they are intense, you should inform your doctor and maybe lower the dosage temporarily.

Where can you buy Parlodel?

The medication is sold in all countries of the world at the regular drugstores but if you want to save on the pills you should order generic Parlodel from our online drugstore. We offer low prices and worldwide shipping including free shipping on orders over $170.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

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