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4RX Store > Medication List > Other drugs > Order Alfacip online

Other Medication (Alfacip)

 
Generic name:
Alfacip
Brand name:
Alfacalcidol
Description:
Alfacip or Alfacalcidol is an active metabolite of vitamin D. It used for vitamin D deficiency, including due to low exposure to the sunlight, as well as conditions in which deterioration and fragility of bones develop (e.g. osteoporosis). The medication comes in different forms and can be given even to infants. However, at this webpage we offer you to buy the drug in a form of capsules that are suitable for adults and kids older than 6 years who are able to swallow tablets.
Indications:
Vitamin D deficiency, Osteomalacia (softening of bones in old age), Osteoporosis, Osteopathy, Insufficient receipt of vitamin D and calcium with food, Malabsorption, Insufficient exposure to sun, Hypocalcemia with hypoparathyroidism, Hypocalcemia due to hypoparathyroidism, Familial hypophosphatemia, Alcoholism, Liver failure, cirrhosis, Fanconi syndrome, Jaundice due to the obstruction of the bile ducts, Gastrointestinal diseases, Rapid weight loss, Pregnancy, Lactation, Breastfed infants with insufficient exposure to sun light
Benefits:
The medication helps to replenish vitamin D deficiency in various conditions and strengthen bones
Synonyms:
Alfa D 3, Buco-D, Calciferol, Condacaps, Condol, Crtron, Crystallina, D-Arthin, D-Tracetten, Daral, Davitamon D, Davitin, De-Rat Concentrate, Decaps, Dee-Osterol, Dee-Ron, Dee-Roual, Deltalin, Deratol, Detalup, Diactol, Divit Urto, Drisdol, Ercalciol, Ergorone, Ergosterol, Ertron, Fortodyl, Geltabs, Infron, Metadee, Mulsiferol, Mykostin, Novovitamin-D, Oleovitamin D, Ostelin, Radiostol, Radstein, Radsterin, Rodine C, Shock-Ferol, Sterogyl, Uvesterol-D, Vigantol, Vio-D, Viosterol, Vitamin D, Vitavel-D
 
   
Alfacip (Generic Alfacalcidol)
 
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appearance from image shown.
 
 
 
 

Order Generic Alfacalcidol Buy Alfacip 1mcg

 

Quantity (max. 2)   Package   Price, USD   You save

 

 

 

 

 

 

 

1
 
  30 caps
 
$65.21 ($66.81)
  $1.61

 

 

 

 

 

 

 

1
 
  60 caps
 
$130.18 ($134.84)
  $4.66

 

 

 

 

 

 

 

1
 
  90 caps
 
$194.23 ($212.64)
  $18.41

 

 

 

 

 

 

 

1
 
  120 caps
 
$255.03 ($281.85)
  $26.82

 

 

 

 

 

 

 

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  Generic Medication guide:

What is the medication named Alfacip?

Alfacip is one of the trademarks for the marketing of the medicinal substance Alfacalcidol. Alfacalcidol is a highly effective active metabolite of vitamin D3 sold also under other names such as Alfa D 3, Buco-D, Calciferol, Condacaps, Condol, and many others. If you need to buy Alfacip, you can as well opt for a generic version of the medication and get the same formulation several times cheaper.

 Trademarks of the medication

NAME
DOSAGE
ROUTE
One Alpha Caps 0.25mcg
Capsule
Oral
One Alpha Caps 1mcg
Capsule
Oral
One-alpha
Liquid
Intravenous
One-alpha
Solution / drops
Oral
Alfacip
Capsule
Oral
One-alpha Sol 0.2mcg/ml
Liquid
Oral

The medication regulates the exchange of calcium and phosphorus in the body. It enhances their absorption in the bowel and kidneys which promotes strengthening of the bones.

After oral intake, the medication is rapidly absorbed in the digestive tract. The time to reach the maximum concentration in blood plasma is from 8 to 18 hours. The onset of action occurs within six hours, the duration of action lasts up to 48 hours.

Unlike natural vitamin D3, the biotransformation of the formulation does not occur in the kidneys, which allows its use in renal dysfunction.

Vitamin D comprises the group of vitamins (D1, D2, D3, D4, D5), from which only two forms (D2 и D3) have an important biological significance.

1
7DHC (cholesterol)
The precursor of vitamin D, forms its supply in the skin.
2
D3 (cholecalciferol)
Beta-UV rays form 80% of vitamin D3 in the skin from cholesterol. Its 20% enter the body with food of animal origin (fish oil, liver, egg yolk).
3
D2 (ergocalciferol)
It enters the body only with plant products (bread, etc.)
4
25(OH)D3 (calcidol)
Then in the liver from both forms as a result of hydroxylation (joining the OH group) is formed 25-OH-hydroxy-cholecalciferol (calcidol). This form is depot and transport, it is determined in the blood to establish the level of vitamin D.
5
1,25(OH)D3 (calcitriol)
Next, in the kidneys with the participation of parathyroid hormone (parathyroid hormone), the second hydroxylation and the formation of the active form occurs 1,25-OH-dihydroxy-cholecalciferol (calcitriol). It is calcitriol that provides the main biological effects of vitamin D in the body.

When is the use of Alfacip indicated?

You can buy generic Alfacip for:

- Vitamin D deficiency;

- Osteomalacia (softening of bones in old age) as a result of insufficient absorption, for example, in the case of malabsorption and post-gastrectomy syndrome.

- Osteoporosis (in postmenopause, associated with use of glucocorticoids, osteopathy (including after kidney transplantation, in kidney failure);

- Insufficient receipt of vitamin D and calcium with food (including in vegan diet);

- Malabsorption, insufficient exposure to sun; - Hypocalcemia due to hypoparathyroidism;

- Familial hypophosphatemia (vitamin D-resistant rickets);

- Alcoholism;

- Liver failure, cirrhosis;

- Fanconi syndrome;

- Jaundice due to the obstruction of the bile ducts;

- Gastrointestinal diseases (celiac enteropathy, persistent diarrhea, Crohn's disease);

- Rapid weight loss;

- Pregnancy (especially with nicotine and drug dependence, multiple pregnancy);

- Lactation;

- Breastfed infants with insufficient exposure to sun light.

If you believe that you have any of the mentioned conditions, we still advise you to consult a doctor and undergo necessary tests to confirm your diagnosis before you buy Alfacalcidol.

When shouldn’t you buy Alfacalcidol?

The medication is contraindicated to be used in:

- Intolerance of allergy to the medication;

- Hypervitaminosis D;

- Plasma calcium level above 2.6 mmol/l;

- Renal osteodystrophy with hyperphosphatemia (vitamin D therapy can be started as soon as serum phosphate levels stabilize).

- Alkalosis with a pH level of venous blood of more than 7.44 (lactate-alkalosis syndrome, Burnett syndrome);

- Metastatic calcification; Hypercalcemia or hypermagnesemia;

- Hypersensitivity to analogues of vitamin D.

Application restrictions:

- Atherosclerosis,

- Pulmonary tuberculosis (active form),

- Sarcoidosis or other granulomatosis,

- Heart failure,

- Chronic renal failure,

- A history of nephrourolithiasis,

- Hyperphosphatemia,

- Senior age (may contribute to the development of atherosclerosis).

How is Alfacip used?

When you buy generic Alfacalcidol, make sure to get the dosage per capsule which is prescribed by your doctor. The recommendations on dosages find below. Preferably, the dosage and course duration are chosen by a doctor individually for each patient. In some cases, the medication must be used throughout all life.

The medication comes in capsules that should be swallowed entirely without chewing and washed down with sufficient water.

If not otherwise prescribed by a doctor, the starting dosage is 1 mcg every day at the same time.

Patients with severe bone diseases are appointed from 1mcg to 3 mcg daily.

For kids older than 6 years and body mass from 20 kg (44 lbs) who can swallow a capsule, the dosage is 1 mcg a day.

In hypoparathyroidism, the dose should be reduced after reaching normal blood calcium levels (2.2-2.6 mmol/L 8.8-10.4 mg/100 ml) or when the product of plasma calcium and phosphate level is 3 5-3.7 (mmol L). For the dosage regimen for infants, consult your pediatrician.

Overdose of Alfacip

In the intake of the dosage 30 exceeding the daily dosage, no negative impact on the heath is observed. Although certain symptoms can develop such as: loss of appetite, general weakness, fatigue, dizziness, headache, nausea, dry mouth, constipation and others. Treatment of an overdose implies discontinuation of the medication use, if needed, low-calcium diet, consumption of sufficient water, in severe cases of hypercalcemia –dialysis, loop diuretics, glucocorticosteroids and calcitonin. In case of an acute overdose, it is recommended to vomit and do gastric lavage.

What adverse effects can Alfacip cause?

When you order Alfacip, you need to be ready that the medication sometimes can cause certain negative effects especially if the dosage is not selected by your doctor individually. They occur as the result of elevation of calcium level in the blood and disappear when the dosage is lowered. The first signs of elevated calcium level are:

- Fatigue;

- Digestive disorders (constipation, nausea, vomiting, heartburn, etc.);

- Loss of appetite;

- Dry mouth;

- Thirst;

- Mild ache in the muscles, joints, bones;

- Weigh loss;

- Increased urination;

- Increased sweating;

- Headache;

- Dizziness;

- Hypersensitivity reactions such as skin rash, itching, etc.

- The frequent adverse effects include: hypercalcemia, hypercalciuria.

- Rare adverse effects include: hyperphosphatemia (to prevent phosphate absorption inhibitors such as aluminum compounds can be prescribed), tachycardia, weakness, headache, dizziness, drowsiness.

- Very rarely can develop: heterotopic calcification (cornea and blood vessels), which disappears after discontinuation of the use, a slight elevation in the level of high density lipoproteins in blood plasma.

In patients with severe renal impairment, hyperphosphatemia may develop; skin allergic reactions (itching) and anaphylactic shock, the latter can be caused by peanut butter, which is part of the drug.

Can Alfacip be used with other medicines?

- The medication can be used with estrogens and antiresorptive medications from different groups in the therapy of osteoporosis.

- The toxic effect of the medication is lowered by the use of vitamin A, tocopherol, ascorbic acid, pantothenic acid, thiamine, riboflavin.

- If the medication is used with digitalis medications, the risk of developing heart rhythm disturbances increases.

- Inducers of microsomal liver enzymes (anticonvulsants, including phenytoin, barbiturates, etc.) increase the metabolism of alfacalcidol, inhibitors reduce (a change in its effectiveness is possible).

- Colestyramine, colestipol, sucralfate, antacids, albumin preparations, mineral oil - reduce the absorption of the medication.

- There is a risk of hyperaluminemia and/or hypermagnesemia in the combined use with antacids or laxatives containing magnesium.

- The use with thiazide diuretics, calcium formulations, medicines that contain vitamin D, there is a risk of hypercalcemia.

- The effect of the medication is lowered when it is used with Calcitonin, derivatives of etidronic and pamidronic acids, and/or glucocorticoids.

- The medication increases the absorption of phosphorus-containing drugs and the risk of hyperphosphatemia.

Special recommendations for Alfacip use

- When you order generic Alfacip, keep in mind that throughout the use it is advised to control the level of calcium and phosphates in the blood. At the start of the therapy, it should be done 1-2 times a week, and in the achievement of the optimal effective dosage, every three to five weeks. In chronic kidney failure, alkaline phosphatase activity should be controlled weekly.

- If you suffer from chronic kidney failure, before the course initiation, the correction of hyperphosphatemia is required. When normalizing the content of alkaline phosphatase in plasma, a corresponding dose reduction is necessary (in order to avoid the development of hypercalcemia).

- The risk of hypercalcemia (elevated above the norm level of calcium in the blood) depends on such factors as degree of demineralization, renal function and dose of the formulation. The condition is developed if the dosage isn’t lowered in the occurrence of the signs of normalized bone structure (for instance, normalization of alkaline phosphatase in plasma. This must be avoided especially in chronic kidney failure.

- For individuals with renal osteodystrophy, it is advised to use the medication with phosphate binders to prevent hyperphosphatemia.

- In case of hypercalciuria (increased calcium level in urine), the medication use is ceased and then continued in lower dosages.

- The medication must not be used with other medicines that contain vitamin D or its derivatives.

- The sensitivity to vitamin D is different in different patients so in some of them the use of the regular dosages can cause hypervitaminosis of vitamin D.

- When the medication is used for newborns, it must be kept in mind that some of them can be very sensitive even to the lowest dosages. - Children who receive vitamin D for long periods of time are at elevated risk of delayed growth. For the prophylaxis of vitamin D deficiency, it is preferable to ensure balanced diet.

- In seniors, the need for vitamin D is higher due to the lowered absorption of the vitamin, lower sun exposure, and increased incidence of kidney failure.

Where can you buy Alfacip?

You can get the medication at a low price and without a prescription if you order Alfacalcidol from our online drugstore. We ship internationally and even offer free shipping on orders over $170 or its equivalent in another currency.

Free prescription
Our doctor prescribes online for free, and there is no doctor’s consultation fee.

Discrete packaging
All orders arrive in discrete unmarked parcels. We leave the shipment description blank.

For more answers see the FAQ section

 

 
 
   
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