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4RX Store > Medication List > Other drugs > Order Eldepryl online

Other Medication (Eldepryl)

Generic name:
Brand name:
Eldepryl is one of the names under which an antiparkinsonian medication Selegiline is sold. The medicationís effect in minimization of Parinsonís disease manifestations is due to irreversible inhibition of MAO (monoamine oxidase). It mainly binds MAO B, oxidizing catecholamines (dopamine, norepinephrine, adrenaline, serotonin). Increases the concentration of dopamine in the central nervous system and eliminates its deficiency in the extrapyramidal system. Find out how the medication is used, what adverse effects it can cause, and other useful information from the full guide.
Parkinson’s disease, Symptomatic parkinsonism
The medication lowers the manifestations of Parkinsonís disease effectively
Intas Pharmaceuticals Ltd.
Intas Pharmaceuticals Ltd.
Selegin, Selgin, Carbex, Jumex, L-Deprenalin, Sd Deprenyl, Selegilina
Eldepryl (Generic Selegiline)
Actual product may differ in
appearance from image shown.

Order Generic Selegiline Buy Eldepryl 5mg


Quantity (max. 2)   Package   Price, USD   You save








  60 tabs
$48.66 ($49.57)








  80 tabs
$59.83 ($62.28)








  100 tabs
$74.43 ($87.69)








  120 tabs
$88.08 ($106.21)








Price: $
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  Generic Medication guide:

Selegiline Application

Parkinson’s disease, symptomatic parkinsonism as monotherapy, early in the course of disease or in a combination with levodopa, combining with peripheral decarboxylase inhibitors or without them.

Short drug info
Trade names Eldepryl, Jumex, Zelapar, Emsam, others
Other names L-Deprenyl; (R)-(–)-N,α-Dimethyl-N-2-propynylphenethylamine; (R)-(–)-N-Methyl-N-2-propynylamphetamine; (R)-(–)-N-2-propynylmethamphetamine
License data US FDA: Selegiline
Pregnancy category

AU: B2

US: C (Risk not ruled out)

Routes of administration By mouth, transdermal (patch)
Legal status

AU: S4 (Prescription only)

CA: Rx-only

UK: POM (Prescription only)

US: Rx-only

Bioavailability 10% (oral), 73% (patch)
Protein binding 94%
Metabolism Intestines and liver
Metabolites N-Desmethylselegiline, L-amphetamine, L-methamphetamine
Elimination half-life

10 hours (oral)

18–25 hours (transdermal)

Excretion Urine


Hypersensitivity, extrapyramidal disorders that are not connected with the deficit of dopamine (essential tremor, Huntington chorea); pregnancy, lactation.

Limitations of Use

Gastroduodenal ulcer, uncontrolled arterial hypertension, cardiac angina, psychosis, glaucoma, thyrotoxicosis, pheocromocitoma, hyperplasia prostate, young patients before 18 years.

Pregnancy and Lactation

FDA pregnancy risk category - C. There is no detailed information about Selegiline successful application for pregnant or lactation women. It is important to hold back from uncontrolled treatment. It is not recommended to buy Generic Eldepryl for young patients.


Selegiline is applied in form of monotherapy in the early course of disease or in a strong combination with levodopa preparations. Both of these cases need primary dose of 5 mg in the morning. The next step is taking preparations in two separate stages in dose of 10 mg. Never forget that support therapy with Selegiline for levodopa can be the reason of often side effects. So, the dose must be minimal.

The preparation can influence over the driving process and other activities. If you feel headache or giddiness you should stop driving or working with mechanisms. Feeling bad, it is important to put on pause your treating therapy and check the treatment indication with the help of doctor and proper tests.

Side Effects

On the side of the nervous system and organs of senses: anxiety, fatigability, giddiness, headache, sleepiness or sleepless, depression, hallucinations, confused consciousness, speech disorder, supraorbital pains, abnormal vision, diplopy.
On the side of the cardiovascular system and blood (blood forming, blood stasis): arrhythmia, orthostatic reactions, high blood pressure, hypostasis.
On the side of the gastrointestinal system: nausea and vomiting, anorexia, dryness of the mouth, dyspepsia, diarrhea, ulcer disease, increased activity of hepatic transaminase.
Others: genital function disorders, urine retention, bronchial allergy, dysury, hyperhidrosis, rash.

Incidence of Eldepryl adverse effects compared to placebo

Adverse Reaction
Selegiline hydrochloride
Number of patients=49
Number of patients=50
Abdominal Pain
Dry mouth
Vivid Dreams
Ache, generalized
Hair Loss
Leg pain
Low back pain
Urinary Retention
Weight Loss

Drug Interaction

It is prohibited to buy Selegiline and take it all together with tricyclics antidepressants. If you are going to take Selegiline all together with sympathomimetics (ephedrine) and preparations that are predicted to suppress central nervous system (including ethanol), it can potentiate their activity.

To exclude serotonin syndrome with mania, hyperhidrosis, fever, you should not take Selegiline all together with fluoxetine, it can be prescribed not less than in 5 weeks after you finished your fluoxetine treatment.
It is a big risk to have delirium, stupor, anxiety condition, excitement and muscle rigidity if you take Seligiline and peptidyl.

Simultaneous appliance of Selegiline with amantadine and anticholinergic preparations increases risks of dangerous development of side effects.

If you are going to order Generic Eldepryl to take it in a combination with levodopa you should afraid of side effects, including anxiety, hyperkinesia, atypical movements, agitation, confused mental state, hallucinations, postural hypotension, cardiac arrhythmia, dysphonia. If you feel bad or suffer from the undesirable side effects in case of combine therapy of Selegiline and levodopa, the dose of levodopa must be checked and reduced up to 30%.

Simultaneous application of the preparation and tricyclic antidepressants, MAO inhibitors and fluoxetine causes such toxic reactions as hyperthermia, rigidity, myoclonia, comatose state.

Dangerous Combinations:
Peroral contraceptives. It is important to be careful to take Selegiline all together with integrated peroral contraceptives (gestogen/ethynilestradiol or levonorgestrel/ethinylestradiol) because they increase Saleginile bioavailability.
Food. Unlike traditional MAO inhibitors of enzymes that are used to suppress both, MAO-A and MAO-B, Selegiline is selective MAO-B inhibitor.

Taking Selegiline in a recommended dose after food with low tyramine does not make the hypertensive changes (so-called cheese effect). So, there is no need to keep diet.
Nevertheless, if you take Selegiline mixed with traditional MAO inhibitors, it is recommended to keep diet (avoid food with high content of tyramine - cheese, yeastors).


Symptoms: cheese syndrome (all MAO types) in form of hypertensive reactions and CAD dysfunction after meal with tyramines (cheese, coffee and others), excitement.
Treatment: vomit induction, gastric lavage, absorbent carbon, symptomatic therapy.

Measures for Safety

It is very important to order Selegiline for patients with hepatic and kidneys disorder, cardiac dysfunction, gastroduodenal ulcer, glaucoma, thyroid body disorder. The preparation must be carefully used for drivers and people working with dangerous mechanisms. MAO must be also considered for long term therapy - 5-7 days. The preparation is prescribed just after 5 days you stopped taking fluoxetine.

Where to Buy Selegiline (Eldepryl) online?

Rxshop is professional distributor of different preparations, including Selegiline that are much easier to buy online. They are available for patients from all over the world. You can buy generics without compromising quality. The goods that you are offered online are produced by the leading pharmaceutical companies. You can get a competent online consultation any time. We guarantee that all drugs from Rxshop are not only cheap but high standard. All preparations do not need special prescription.

You may order Selegiline from different parts of the world, like Australia, Great Britain, India, USA and others. Your order form must be filled correctly according to the state rules that you can learn from the website. All medications are approved by regulative organs to be safe to use.

Generic Eldepryl (Selegiline) Shipping by 4Rxstore

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Discrete packaging
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Product Reviews:

May / 15 / 2018 Mark Smith   USA, Venetia
  Arrived safely, Well packaged and quick delivery.
Dec / 21 / 2017 Eduardo Wood   USA, Loomis
  Repeat purchase from trusted seller, good products and prices.

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