Generic Medication guide:
Clinical Medical Group
Selective inhibitor of acetyl cholinesterase for brain. The preparation is approved to treat Alzheimer disease.
You can buy Generic Exelon in form of pills and patches. The pill of Exelon contains the main active component - Rivastigminehydrotartrate 2.4 mg, 4.8 mg, 7.2 mg or 9.6 mg (it is equivalent to 1.5 mg, 3 mg, 4.5 mg or 6 mg of Rivastigmine);
Additional components: colloidal silicon dioxide,hypromellose, magnesium stearate, microcrystalline cellulose.
Early or medium stage of dementia of Alzheimer type (Alzheimer disease, potential Alzheimer disease). Early or medium stage of dementia of Parkinson’s disease.
Idiosyncrasy to Rivastigmine and other drug components. It is also not recommended to order Rivastigmine for patients, suffering from hepatic disorders and young patients before 18 years.
Application of Special Attention
Generic Exelon as the rest of others cholinomimetic drugs must be taken carefully, especially for patients, suffering from the sick sinus syndrome or conductibility(sinuatrial block, atrioventricular block).
Cholinergy stimulation increases the stomach secretion of hydrochloric acidthat leads to the urinary tract obstruction and convulsive disorder. The treatment therapy with Exelon needs special attention to prevent all before mentioned conditions.
Exelon must be carefully taken for patients, suffering from bronchial allergy or obstructive disorders of anatomical airways.
The preparation must be carefully used all together with others cholinomimetic agents.
If you are in the stage to find the right dose, you can meet different side effects in the period of dose escalation. Dose changing leads to the list of possible unavailable effects. Otherwise, you should stop therapy.
Pregnancy and Lactation Period
The results of the latest experiments show that Rivastigmine does not take the dose escalation. Nevertheless, the preparation is approved to take by pregnant and women in lactation just in case if expected use for mother is much bigger than the use for baby. There is no information about Exelon ability to penetrate with milk.
Dosage and Administration
According to the list of indications, Generic Exelon should be taken twice a day - morning and evening. The primary dose of Exelon is 1,5mg twice a day. If you suffer from chronic allergy to one or another cholinergic medication, it is recommended to make primary dose no more than 1 mg twice a day. You can make the dose of 3 mg twice a day in two weeks or later if your health condition is ok. Having high tolerability to 3 mg dosage, you can take the preparation in dose of 4,5mg and 6 mg twice a day. Every next dose needs two weeks to be increased.
The maintaining dose of Exelon is 1,5-6 mg twice a day. The maximum dose is 6 mg twice a day. If you stopped taking the preparation for few days, it is important to start from the minimum dose of 1 mg to prevent undesirable side effects.
The transdermal system of Exelon is externally used in form of patches according to special recommendations. To have the right dose it is necessary to follow the prescription about the application technic and place. The treatment must be provided under the doctor’s control or other specialist, who has enough experience to treat patients with Alzheimer dementia.
To find the right dose, it is necessary to define the factual Rivastigmine content in the system of treatment. To get maximum effect, it is recommended to use medical patch at the same time every day. If the time is missed, you should change the used system as far as you remind it.
It is recommended to order Generic Exelon to take it carefully to avoid undesirable side effects:
Gastrointestinal system: vomit, sickness, appetite loss, diarrhea, dyspepsia, stomachache, pancreatitis, gastrointestinal bleeding, peptic ulcer, hepatic function disorders.
Central nervous system: headache, giddiness, sleepiness, shivering, agitation, depression, sleepless, mental confusion, hallucinations, collapse, convulsion.
Cardiovascular system: elevation in arterial blood pressure, arrhythmia, heart attack, breast pang.
Skin manifestations: rash, sweatiness.
Other possible side effects: asthenia and fatigability, weight loss, feeling generally unwell.
The most of medical cases inform that Exelon overdosing is not dangerous as it is not characterized with dangerous clinical effects. There is no need to stop treatment. The symptoms of overdosing are: high blood pressure, vomit, diarrhea, hallucinations. It is not recommended to take preparation for a day or two or even more. If you have vomit, sickness, it is better to take antiemetic agents to stop vomit and better your health condition.
The preparation must be carefully used for risk patients, suffering from sick sinus syndrome, arrhythmia, erosive-ulcerous gastrointestinal damages, respiratory diseases, urinary tract obstruction, convulsions. There are no recommendations to buy Rivasgtigmine for patients, suffering from bronchial allergy, especially in attack phase. The doctor’s control is recommended.
Effects on the Ability to Drive and Use Machines
It is recommended to use medications carefully, if you are going to use machines or drive a car, especially if you need to be well-concentrated and have high speed cognitive functions.
Rivastigmine is mostly metabolized by the way of hydrolysis with the participation of esterase. The metabolism with the participation of the main isoenzymes of cytochrome P450 system is minimal. Consequently, pharmacokinetic influence of Rivastigminewith other medications is improbable.
If you take Exelon all together with anticholinergic agents, there is a risk to change their anticholinergic activity.
The effect from depolarizing muscle relaxants can be increased.
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