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4RX Store > Medication List > Other drugs > Order Niacin online

Other Medication (Niacin)

Generic name:
Brand name:
Nicotinic acid
Niacin also known as nicotinic acid is a substance that is used to replenish the lack of vitamin B3/PP, improve blood circulation, especially in brain circulation disorders; it helps to heal wounds and ulcers, accelerates the healing in digestive tract diseases, and so on. The full list of indications, as well as the recommendations on the dosages, precautions, descriptions of side effects and how they can be avoided you can find in the guide below.
Prevention and treatment of pellagra (vitamin PP/B3 deficiency), Atherosclerosis, Hypoacid gastritis, Spasms of blood vessels (brain, kidneys, limbs), Facial nerve neuritis, Long healing wounds and ulcers, Hyperlipidemia, Hypercholesterolemia, Hypertriglyceridemia, Endarteritis obliterans, Raynaud’s disease, Migraine, Cerebrovascular circulation violation, Ischemic stroke, Angina pectoris, Hartnup disease, Hypercoagulation, Intoxication, Infectious diseases, Gastrointestinal tract diseases
The medication improves blood circulation, replenishes vitamin PP/B3 in its deficiency, and normalizes lipids level in the blood
Cipla - Caring for life
Cipla - Caring for life
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Niacin (Generic Nicotinic acid)
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  Generic Medication guide:

What is Niacin and when is it used?

Niacin is one of the brand under which the compound with an unpatented international name nicotinic acid is sold. You can buy nicotinic acid under other less known names to get it cheaper.

The medication is used for:

- Prevention and treatment of pellagra (vitamin deficiency PP);

- Atherosclerosis;

- Hypoacid gastritis;

- Spasms of blood vessels (brain, kidneys, limbs);

- Facial nerve neuritis;

- Long healing wounds and ulcers of various localization and genesis.

- Hyperlipidemia (including hypercholesterolemia, hypertriglyceridemia);

- Endarteritis obliterans;

- Raynaud's disease;

- Migraine;

- Cerebrovascular circulation violation including ischemic stroke (complex therapy);

- Angina pectoris;

- Hartnup disease;

- Hypercoagulation;

- Intoxication;

- Infectious diseases;

- Gastrointestinal tract diseases.

Short drug info
Trade names Niacin, Acide Nicotinique, Akotin, Anti-Pellagra Vitamin, Apelagrin, Bionic, Daskil, and others
Routes of administration Intramuscular, by mouth
Use during pregnancy Possible in low dosages
Biological half-life 20–45 min

The mediation has hypocholesterolemic, hypolipidemic, vasodilating, replenishing vitamin PP deficiency (B3) effects. It is included in the group of enzymes that transport hydrogen. Niacin regulates redox processes (oxidation and restoration), tissue respiration, protein and fat synthesis, glycogen breakdown, inhibits lipolysis in adipose tissue, reduces the rate of synthesis of very low density lipoproteins (bad cholesterol), and normalizes the lipid composition of the blood (reduces the level of total cholesterol, bad cholesterol, triglycerides and increases the level of good cholesterol).

Nicotinic acid dilates blood vessels including the vessels of the brain, improves microcirculation, and prevents the formation of thrombus. Nicotinic acid is also found in foodstuffs but if the food rich in it is consumed insufficiently and the disorders related to it develop, it is advised to use this vitamin in pills.

When is the use of Niacin contraindicated?

You should not buy generic Niacin and use it in:

- Allergy or intolerance of the substance;

- Kids under 12 years of age;

- Acute ulcer of the stomach and duodenum;

- Severe liver impairment;

- Gout;

- Severe arterial hypertension (uncontrollable elevation of arterial tension);

- Hyperuricemia.

- Decompensated diabetes mellitus;

- Kidney stone disease;

- Recent myocardial infarction;

- A sudden decrease in peripheral vascular resistance in history.

These are the contraindications for pills use. If you plan to buy nicotinic acid in form of injections, please read the corresponding recommendations.

Use of Niacin during pregnancy and lactation

The medication can be used in pregnancy and lactation but in small doses and only if a doctor approves.

How is Niacin used?

The pills of nicotinic acid are taken orally after a meal.

- In deficiency of B3 vitamin, adults should take 100 mg two to four times a day for 15-20 days. Kids aged older than 12 years should be given 50 mg two to three times a day.

- For other diseases, adults should use 50mg twice a day. Kids older than 12 years are given 25 mg twice a day.

- The highest dosages for adults – 100 mg single dosage and 500 mg total daily dosage. In atherosclerosis (in the absence of side effects), a single dose can be gradually increased to 500 mg-1 g, and the daily dose to 2-3 g.

- The highest dosage for kids is 50 mg single dosage and 200 mg daily dosage.

Nicotinic acid overdose

Symptoms include dilation of the peripheral vessels resulting in skin reddening, nausea, vomiting, diarrhea, heartburn, brown spots on the skin, dizziness, jaundice of the skin, skin paresthesia (tingling, burning sensation, sensation of heat, crawling sensation).

In the occurrence of these symptoms, it is required to stop using the medication and undertake measures to eliminate the symptoms.

What adverse effects can Niacin cause?

When you buy nicotinic acid, you should know that it can cause such adverse effects as:

- Cardiovascular system: flushes that can be accompanied by shortness of breath, irregular or rapid heartbeat, sweating, chills, swelling.

- Central nervous system: headache, dizziness, skin paresthesia (tingling, burning sensation, sensation of heat, crawling sensation). -Skin: reddening of the face and upper body with a tingling and burning sensation, dry skin and mucous membranes of the eyes, debilitating skin itching, rashes.

- Liver and bile ducts: in long-term use - fatty liver, increased blood levels of aspartate aminotransferase (ATS), lactate dehydrogenase (LDH), alkaline phosphatase.

- Metabolism: in long-term use in high doses – impaired tolerance of glucose, increased glucose levels, increase of uric acid levels in the blood, hypophosphatemia.

- Other: allergic reactions including urticaria. Very rarely the use of the medication in high doses in individuals with cardiac ischemia can increase the frequency of atrial arrhythmias, as well as acanthosis (brown spots on the skin with a velvety surface).

Rarely, edema of the retina may occur. These symptoms are unstable and disappear after discontinuation of the drug.

The use of high doses of nicotinic acid can cause: hyperpigmentation, seizures, diarrhea, nausea, vomiting, anorexia, exacerbation of stomach ulcers, jaundice, amblyopia, decreased platelet count, prolonged prothrombin time.

Insomnia, myalgia, arterial hypotension, and rhinitis may occur. Possible blurred vision, swelling of the eyelids, myopathy, exfoliative dermatitis.

Cases of rhabdomyolysis when using nicotinic acid with Lovastatin have been reported.

The incidence of nicotinic acid adverse effects compared to placebo

Placebo (Number of patients = 157) %
Nicotinic acid 500 mg (Number of patients = 87) %
Nicotinic acid 1000 mg (1500 mg) (Number of patients = 110) %
7 (10)
5 (6)
Cough, Increased
3 (2)
0 (2)
8 (0)
5 (5)
68 (69)

Can Niacin be used with other medicines?

If you use any medicines at the time you want to buy generic nicotinic acid, make sure to consult your healthcare provider.

- The medication is incompatible with B1, B12, B6, aminophylline, salicylates, tetracycline, sympathomimetics, and hydrocortisone.

- Acute vascular insufficiency may occur if during the therapy with the medication a patient consumes alcohol.

- Oral contraceptives and isoniazid reduce the conversion of tryptophan to nicotinic acid and thus may increase the need for nicotinic acid.

- The medication lowers the effectiveness and toxicity of probenecid, neomycin, barbiturates, anti-TB drugs, sulfonamides.

- Antibiotics can enhance skin reddening caused by nicotinic acid.

- Aspirin lowers the effect of reddening of the skin caused by Niacin.

- It is not recommended to use Lovastatin and/or Pravastatin with nicotinic acid as there is a risk of enhanced adverse reactions up to rhabdomyolysis (muscle cells destruction).

- The medication should be cautiously used with blood tension lowering medications as it can enhance their effect.

- Niacin should be cautiously used with anticoagulants (blood thinners) and aspirin since there is a risk of internal bleeding.

- The medication potentiates the effect of fibrinolytic agents, antispasmodics and cardiac glycosides, and the toxic effect of alcohol on the liver.

- The simultaneous use with beta-adrenergic receptors blockers or with methyldopa leads to a strong decrease in blood pressure; with antidiabetic agents - to the potentiating of the glucose-lowering effect of the latter.

Special recommendations for nicotinic acid use

When you order Niacin before using it, make sure to read this section. To minimize the chance of adverse reactions occurrence and better tolerated treatment it is recommended to:

- Control the level of glucose and liver function to timely notice if there are negative effects of the drug on these systems.

- Take the pills only after or with a meal as it makes the absorption gradual and lowers the likelihood of adverse effects.

- Do not take the pills with hot drinks (especially coffee) or alcohol;

- Do not shower or take a warm bath right after taking a pill.

Besides these precautions:

- It should be carefully used by people with history of internal bleedings (including eye hemorrhages), glaucoma, kidney failure, moderate arterial hypotension, high acidity gastritis, peptic ulcer of the stomach and duodenum (in remission), alcohol abusers, patients with unstable angina pectoris, and acute myocardial infarction receiving nitrates, calcium channel antagonists, and beta blockers.

- In the long-term use in high dosages, the medication can cause fatty liver which is why the control over the liver function is needed. To prevent liver complications, it is recommended to include foods rich in methionine (cottage cheese) in the diet or to use methionine and other lipotropic drugs.

- It is needed to regularly monitor the level of uric acid in the blood due to its possible increase as a result of prolonged therapy.

- The pills contain glucose which should be considered by people with diabetes. - It is not advised to use nicotinic acid for the correction of dyslipidemia in patients with diabetes.

Where can you buy Niacin?

To get the mediation cheap and without Rx, you can order generic Niacin from our online drugstore. We ship all products worldwide and offer discounts for our loyal customers.

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